33005560
Description
Mind Map by maitha alyahyaee, updated 8 months ago
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Created by maitha alyahyaee
about 3 years ago
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lymphoma
- DD of lymphadenopathy
- general/local?
- site?
- infection? autoimmune? malignancy?
- general/local?
- Anatomy of lymph nodes
- Scattered ,Covered by a capsule of dense
connective tissue, Trabeculae divide the
node into ( Cortex / Medulla )
- cortex
- Follicles of B cells, Germinal centers
- Rich in T cells, Dendritic cells
- Rich in T cells, Dendritic cells
- Follicles of B cells, Germinal centers
- medulla
- Medullary cord,
Medullary sinus
- Medullary cord,
Medullary sinus
- cortex
- Scattered ,Covered by a capsule of dense
connective tissue, Trabeculae divide the
node into ( Cortex / Medulla )
- treatment
- Low-grade NHL (initial stages): radiotherapy
Low-grade NHL (advanced stages): palliative chemo
High-grade NHL: chemotherapy
- R-CHOP Therapy
- ABVD
- BEACOPP
- Low-grade NHL (initial stages): radiotherapy
Low-grade NHL (advanced stages): palliative chemo
High-grade NHL: chemotherapy
- classification
- hodgkin lymphoma HL
- Nodular sclerosis,
Mixed cellularity,
Lymphocyte-rich,
Lymphocyte-depleted
- reedsternberg cells
- sequence/order fashion
- B symptoms
- high inflammation (cytokines)
- high inflammation (cytokines)
- B symptoms
- sequence/order fashion
- Nodular sclerosis,
Mixed cellularity,
Lymphocyte-rich,
Lymphocyte-depleted
- NHL
- b cells
- follicular, diffuse
- follicular, diffuse
- t cells
- poor prognosis
- random
- random
- b cells
- hodgkin lymphoma HL
- risk factors
- genetic mutations (myc,bcl2)
- viral infection (EBV, HTLV1)
- pathogenesis
- Age, male, AID
- environmental factors
- genetic mutations (myc,bcl2)
- complications
- weakened immunity
- pressing nearby structures
- spread
- nausea, fatigue, infertility
(treatment related)
- psychological
- weakened immunity
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