37128153
Description
Mind Map by Jasper McClellan, updated more than 1 year ago
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Created by Jasper McClellan
over 2 years ago
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Exam 2: Thiazolidinediones
- Pharmacological action
- Decrease insulin resistance
- In turn increases
sketeletal muscle and
adipose tissue uptake
- In turn increases
sketeletal muscle and
adipose tissue uptake
- Decrease liver
glucose
production
- Decrease insulin resistance
- Pharmacokinetics
- Metabolized in liver
- Excreted via feces (mostly) and urine
- Metabolized in liver
- Adverse effects
- Unintended ovulation
- Bladder cancer
- Fluid retention
- Increased cholestrol
- Risk for bone fracture
- URIs/
sinusitis
- Headaches
- Muscle aches
- Unintended ovulation
- Contraindications
- Liver impairment
- Bladder cancer
- Heart failure
- Liver impairment
- Drug interactions
- Insulin
- Fluid retention
- Hypoglycemia
- Fluid retention
- Hypoglycemia
- Gemfibrozil
- Coenzyme Q10
- Ketoconazole
- Chromium
- Gemfibrozil
- Insulin
- Extra information
- Also known as glitazones
- Pioglitazone is a medication in this category
- Also known as glitazones
- Nursing interventions
- Liver Function Tests at baseline & every 3-6 months
- Liver Function Tests at baseline & every 3-6 months
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