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37128153
Exam 2: Thiazolidinediones
Description
Mind Map on Exam 2: Thiazolidinediones, created by Jasper McClellan on 11/07/2022.
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Jasper McClellan
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Jasper McClellan
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Resource summary
Exam 2: Thiazolidinediones
Pharmacological action
Decrease insulin resistance
In turn increases sketeletal muscle and adipose tissue uptake
Decrease liver glucose production
Pharmacokinetics
Metabolized in liver
Excreted via feces (mostly) and urine
Adverse effects
Unintended ovulation
Bladder cancer
Fluid retention
Increased cholestrol
Risk for bone fracture
URIs/ sinusitis
Headaches
Muscle aches
Contraindications
Liver impairment
Bladder cancer
Heart failure
Drug interactions
Insulin
Fluid retention
Hypoglycemia
Hypoglycemia
Gemfibrozil
Coenzyme Q10
Ketoconazole
Chromium
Extra information
Also known as glitazones
Pioglitazone is a medication in this category
Nursing interventions
Liver Function Tests at baseline & every 3-6 months
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