Drug Metabolism

Description

Notes from Doctors in Training
snlogel
Mind Map by snlogel, updated more than 1 year ago
snlogel
Created by snlogel almost 11 years ago
240
0

Resource summary

Drug Metabolism
  1. Phase I
    1. Reactions
      1. Reduction
        1. Oxidation
          1. Hydrolysis
          2. Metabolites
            1. Slightly polar
              1. Water soluble
                1. Active
              2. Phase II
                1. Reactions
                  1. Acetylation
                    1. Methylation
                      1. Sulfation
                        1. Glucuronidation
                        2. Metabolites
                          1. Very polar
                            1. Inactive
                          2. Disulfiram-like reaction
                            1. Metronidazole
                              1. Certain cephalosporins
                                1. Procarbazine
                                  1. 1st generation sulfonylureas
                                  2. Zero order kinetics
                                    1. Phenytoin
                                      1. Ethanol
                                        1. Aspirin
                                        2. TCAs
                                          1. Imipramine
                                            1. Clomipramine
                                              1. Amitriptyline
                                                1. Nortriptyline
                                                Show full summary Hide full summary

                                                Similar

                                                Cranial Nerves
                                                snlogel
                                                Platelets
                                                snlogel
                                                Psychosis and Antipsychotic Drugs
                                                snlogel
                                                Hemolytic Anemias
                                                snlogel
                                                Cardiac Embryology
                                                snlogel
                                                Neurotransmission and Second Messengers
                                                snlogel
                                                Liver Pathology
                                                snlogel
                                                Hepatitis
                                                snlogel
                                                Antidepressants
                                                snlogel
                                                Studies and Diagnostic Tests
                                                snlogel
                                                Bias and Error
                                                snlogel