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4687908
Immune System
Description
Science Board Review (Microbiology) Mind Map on Immune System, created by dsandoval on 29/02/2016.
No tags specified
science
biology
microbiology
board review (microbiology)
science
Mind Map by
dsandoval
, updated more than 1 year ago
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Created by
dsandoval
over 8 years ago
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Resource summary
Immune System
Cell-mediated Immunity
T-cells
defense against infection
like mycobacterium tuberculosis
viral/fungal
Allergic response
Ex: poison oak
Antibody-mediated (Humoral) Immunity
B-Cells
defense against infection
opsonizes bacteria
neutralizes toxins/viruses
allergic response ex: Hay fever
autoimmunity
SPECIFICITY OF IMMUNE RESPONSE
Involves: recognition, activation, and response
may be natural (innate)/acquired (adaptive)
NATURAL IMMUNITY
Non-specific
not acquired from previous exposure
Does not improve after exposure
NO memory
Host defenses
Skin, mucous membranes
Natural killer cells
Phagocytosis
Inflammation
ACUIRED IMMUNITY
after exposure
improves w/ repeated exposure
Mediated by antibodies and T-cells
Long-term memory
Can be passive/active
ANTIGENS
Foreigness: Non-self
Dosage, route and timing of exposure
CELLS OF IMMUNE SYSTEM
Made up of Leukocytes
Granulocytes
Neutrophils, eosinophils, basophils
Lymphocytes
T-cells, B-cells, natural killer cells
Monocytes
precursor to macrophage
Dendritic Cells
APC's
key regulator
Produced in bone marrow
T Cells
65-80% of lymphocytes
Arise in bone marrow
T-cytotoxic cell
directly kill and attack
CD 4 T cell
produce cytokines, stimulate macrophages, NK cells, dendritic cell and other T-cell
B Cells
produce antibodies
Are APC's
Can form memory cells
MACROPHAGES
3 main funcitons
Phagocytosis
Antigen transportation
Cytokine production
Nk cells
kill viruses/tumor infected cells
Non-specific
kill w/o antibody
PMN's
most numerous WBC 60%
capable of phagocytosis
1st line of defense
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