5000393
Description
Mind Map by Amal Sami7018, updated more than 1 year ago
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Created by Amal Sami7018
over 8 years ago
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anti influenza drugs
- Ion channel disrupters
- Tricyclic amines of adamantane
- they inhibit penetration and uncoating of the virus by:
- inhibition of matrix protein
- inhibition of hemagglutinin protein
- inhibition of matrix protein
- both are used to treat influenza A infection
- Rimantidine is more potent and shows less CNS side
effects than Amantidine
- they inhibit penetration and uncoating of the virus by:
- Tricyclic amines of adamantane
- Neuraminidase (NA) inhibitors
- they are competitive and reversible inhibitors of NA
and they are active against both influenza A
and B viruses
- administered by inhalation
- administered by inhalation
- administered orally
- It's a prodrug that is activated by
hepatic esterases
- administered orally
- administered IV
- administered IV
- they are competitive and reversible inhibitors of NA
and they are active against both influenza A
and B viruses
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