give examples to
illustrate the importance
of organic synthesis in
research for the
production of useful
products
explain why sensitive methods of chemical analysis
are important when planning and monitoring organic
syntheses
deduce the empirical formulae, molecular formulae and
structural formulae from data drawn from combustion
analysis, elemental percentage composition,
characteristic reactions of functional groups, infrared
spectra, mass spectra and nuclear magnetic resonance
predicting the properties of unfamiliar compounds
containing one or more of the functional groups included in
the specification, and explain these predictions ii planning
reaction schemes of up to four steps, recalling familiar
reactions and using unfamiliar reactions given sufficient
information iii selecting suitable practical procedures for
carrying out reactions involving compounds with functional
groups included in the specification iv identifying appropriate
control measures to reduce risk during a synthesis based upon
data of hazards v understanding why, in the synthesis of
stereo-specific drugs, it is important to understand the
mechanism of the reaction and how this can help to plan the
synthesis
explain why the pharmaceutical industry has adopted
combinatorial chemistry in drug research, including
passing reactants over reagents on polymer supports
describe and carry out, where appropriate, the preparation of a compound, eg
cholesteryl benzoate (a liquid crystal) and of methyl 3-nitrobenzoate, requiring
some of the following techniques: i refluxing ii purification by washing, eg with
water and sodium carbonate solution iii solvent extraction iv recrystallization v
drying vi distillation vii steam distillation viii melting temperature determination ix
boiling temperature determination.