5251941
Description
Quiz by Jeku Jacob, updated more than 1 year ago
|
Created by Jeku Jacob
over 8 years ago
|
|
Question 1
Question
Which of the following mechanisms best describes the mode of action of the sulphonylurea class of drugs?
Answer
-
Stimulates insulin synthesis.
-
Enhances insulin binding to the beta cell insulin receptor.
-
Stimulates insulin secretion.
-
Stimulates conversion of proinsulin to insulin and C-peptide.
-
Stimulates beta cell proliferation.
Question 2
Question
The deterioration in glycaemic control over time seen in patients with type 2 (non-insulin-dependent) diabetes mellitus is primarily due to:
Answer
-
medication non-compliance.
-
increasing insulin resistance.
-
increasing obesity.
-
decreasing insulin secretion.
-
reduced energy expenditure
Question 3
Question
Which of the following drugs used in diabetes treatment is most likely to cause hypoglycemia?
Answer
-
Repaglinide.
-
Metformin.
-
Acarbose.
-
Rosiglitazone.
-
Orlistat.
Question 4
Question
In a patient with Type 2 diabetes which of the following co-existing clinical situations is the strongest contraindication to the use of a thiazolidinedione drug?
Answer
-
Fatty liver disease.
-
Peripheral vascular disease.
-
Severe congestive cardiac failure.
-
Proliferative diabetic retinopathy.
-
Serum creatinine 200μmol/L.
Question 5
Question
In patients with Type 1 Diabetes, the greatest benefit in using a long acting insulin analogue is in reducing which of the following
Answer
-
Diabetic Retinopathy
-
Nocturnal hypoglycemia
-
insulin hypersensitivity
-
preprandial hyperglycemia
-
microalbuminuria
Question 6
Question
Glucagon-like peptide–1, secreted postprandially by the L-cells in the intestine, increases which of the following?
Answer
-
Gastric emptying.
-
Body weight.
-
Insulin secretion.
-
Hepatic glucose output.
-
Insulin sensitivity (sulphonylurea, thiazolidinediones)
Want to create your own Quizzes for free with GoConqr? Learn more.