Tumours- Pathoanatomy 3rd Year 1st Sem- PMU

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Tumours- Pathoanatomy 3rd Year 1st Sem- PMU
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Pregunta 1

Pregunta
Do tumours have a spontaneous regression and return to normal structures?
Respuesta
  • True
  • False

Pregunta 2

Pregunta
Is it possible to develop a squamous-cell carcinoma in the vagina?
Respuesta
  • True
  • False

Pregunta 3

Pregunta
Does glomus tumor belong to vascular tumors?
Respuesta
  • True
  • False

Pregunta 4

Pregunta
Does the parenchyma of carcinomas have a diffuse structure?
Respuesta
  • True
  • False

Pregunta 5

Pregunta
Is it possible on the basis of molar pregnancy (hydatidiform mole) to develop a choriocarcinoma?
Respuesta
  • True
  • False

Pregunta 6

Pregunta
The carcinomas metastasise primarily through:
Respuesta
  • blood-borne
  • lymph

Pregunta 7

Pregunta
The more differentiated malignant tumors are:
Respuesta
  • more malignant
  • less malignant

Pregunta 8

Pregunta
The infiltrative growth is one of the most important indication of:
Respuesta
  • malignant tumors
  • benign tumors

Pregunta 9

Pregunta
The lipoma is a benign tumor of:
Respuesta
  • epithelial origin
  • mesenchymal origin

Pregunta 10

Pregunta
The papilloma is a benign tumor of:
Respuesta
  • the lining epithelium
  • the glandular epithelium

Pregunta 11

Pregunta
Do precanceroses (precancerosis) have a regression?
Respuesta
  • True
  • False

Pregunta 12

Pregunta
Is the fibroid a benign tumor of the mature connective tissue?
Respuesta
  • True
  • False

Pregunta 13

Pregunta
Is it possible for the benign tumors to have no capsule?
Respuesta
  • True
  • False

Pregunta 14

Pregunta
Does the tumor growth have a compensatory-adaptive character for the body?
Respuesta
  • True
  • False

Pregunta 15

Pregunta
Does the basement membrane destroy at “ca in situ” (CIS)?
Respuesta
  • True
  • False

Pregunta 16

Pregunta
The parenchyma of carcinomas has:
Respuesta
  • a cellulal structure
  • a diffuse structure

Pregunta 17

Pregunta
The sarcomas metastasise primarily through:
Respuesta
  • the lymphs (lymphatic)
  • blood-borne

Pregunta 18

Pregunta
The leukoplakia is a precancerous of:
Respuesta
  • gastric mucosa
  • buccal mucosa

Pregunta 19

Pregunta
What kind of jaundice is developed in carcinoma of Papilla Vateri?
Respuesta
  • obstructive (mechanical)
  • hemolytic

Pregunta 20

Pregunta
An adenoma is a benign tumor of:
Respuesta
  • epithelial origin
  • glandular origin

Pregunta 21

Pregunta
Point out the characteristic features of the carcinomas:
Respuesta
  • The cells are commonly arranged in nests
  • Microscopically viewed they are a type of fish meat
  • They metastasize primarily through blood-borne
  • The parenchyma cells indicate an apathy

Pregunta 22

Pregunta
The basal-cell carcinoma (BCC) can be localised mostly in:
Respuesta
  • the skin of the forearm
  • the skin of the lower limbs
  • the skin of the palms
  • the skin of the face

Pregunta 23

Pregunta
Match the correct description with the right type of carcinoma: “It is developed in the mucous membranes,which are covered with cylindrical epithelium and in organs with glandural structure.”
Respuesta
  • Transitional cell carcinoma (TCC)
  • Adenocarcinoma
  • Squamous cell carcinoma
  • Sarcoma

Pregunta 24

Pregunta
A carcinoma whose cells show no resemblance to the tissue from which the tumor originates is called:
Respuesta
  • Undifferentiated carcinoma
  • Organoid carcinoma
  • Scirosum carcinoma
  • Histoid carcinoma

Pregunta 25

Pregunta
The proof of mucus in gelatinous (mucinous) carcinoma is performed in staining with:
Respuesta
  • PAS-reaction
  • Van Gieson’s stain
  • Toluidine blue
  • Gomori’s trichrome stain

Pregunta 26

Pregunta
Which of the following is characteristic of the adenocarcinoma’s macroscopic type?
Respuesta
  • It’s in the form of “a bowl”
  • It’s in the form of “a cauliflower”
  • It’s in the form of a round non-healing face ulcer
  • It’s in the form of a very tight node on the face

Pregunta 27

Pregunta
Provide a biological and histological characteristic of the benign tumors:
Respuesta
  • It is composed of anaplastic cells
  • The cells have a high mitotic activity
  • The benign tumor is characterized by expansive growth
  • Recurrence and metastasis in cells

Pregunta 28

Pregunta
The squamous papilloma occurs most frequently:
Respuesta
  • in the oral mucosa
  • on the skin
  • in the bladder
  • in the larynx

Pregunta 29

Pregunta
Match the following data from the histological picture with a psammomatous meningioma:
Respuesta
  • The epithelium in the cysts grows in the form of papillae
  • Cystic structure
  • Calcium deposits
  • Signet ring cells

Pregunta 30

Pregunta
The lymphangioma is most often located :
Respuesta
  • in the skin of the face
  • in the sella turcica area (turkish chair)
  • on the finger's phalanges
  • in the lips and the tongue

Pregunta 31

Pregunta
The squamous cell carcinoma can develop in the nasal cavities and the bronchi on the basis of:
Respuesta
  • hypoplasia
  • histological accommodation
  • anaplasia
  • metaplasia

Pregunta 32

Pregunta
The sarcomas’ macroscopic appearance is like:
Respuesta
  • gelatinous mass
  • cauliflower
  • fish meat
  • cartilage density

Pregunta 33

Pregunta
What is characteristic of Hodgkin disease?
Respuesta
  • Obliterated lymph node structure
  • Diverse cellular composition
  • Monomorphic cellular composition
  • Reed-Sternberg cells

Pregunta 34

Pregunta
Which of the following histological features are characteristic for the Non-Hodgkin’s malignant lymphoma?
Respuesta
  • Obliterated lymph node structure
  • Preserve lymph node structure
  • Monomorphic cellular composition
  • Polymorphic cellular composition

Pregunta 35

Pregunta
In order to proof the availability and determination of collagen in connective tissue neoplasm (tumour) which of the following staining is used?
Respuesta
  • Van Gieson’s stain
  • Congo red stain
  • Toluidine blue
  • PAS-reaction

Pregunta 36

Pregunta
Is it true that:
Respuesta
  • The benign tumors grow expansively while malignant-infiltrative
  • The malignant tumors as well as some of the benign ones lead to death
  • The benign tumors can recur
  • Some malignant tumors have a pseudocapsule,while many of the bening tumors don’t have a capsule

Pregunta 37

Pregunta
Which of the following tumors is malignant?
Respuesta
  • Chondrosarcoma
  • Adenoacanthoma
  • Chorioepitelioma
  • Carcinoma planocellulare

Pregunta 38

Pregunta
A dermoid cyst is:
Respuesta
  • a mature teratoma
  • a tumor of the pigmented tissue
  • a skin pseudocyst
  • a cystadenocarcinoma

Pregunta 39

Pregunta
Carcinomas are characterised by:
Respuesta
  • an expansive growth
  • primarily lymphogenic metastasis
  • cellular atypia
  • primarily hematogenous metastasis

Pregunta 40

Pregunta
Squamous cell carcinoma has:
Respuesta
  • slivers construction
  • psamoma bodies
  • cancer pearls
  • nest construction

Pregunta 41

Pregunta
Melanoma malignum:
Respuesta
  • it can occur from naevus pigmentosus
  • it cannot be achromatic
  • should not be excised prior to diagnose biopsy
  • if suspected to be excised very broadly and deeply

Pregunta 42

Pregunta
Which of the following changes are tumor processes?
Respuesta
  • chondroma
  • naevos pigmentosus
  • mola hydatidosa
  • seminoma

Pregunta 43

Pregunta
Basal cell carcinoma:
Respuesta
  • develops at only fair on the glabrous part of the face
  • gives early distant metastases
  • it is made of cylindrical cells
  • it is made of epithelioid cells

Pregunta 44

Pregunta
Carcinoids are:
Respuesta
  • tumor process
  • benign tumors
  • malignant tumors
  • hyperplastic process

Pregunta 45

Pregunta
The comparison: a ring with a stone inward is used in:
Respuesta
  • fatty degeneration of hepatocytes
  • mucus carcinoma
  • vacuolar fatty degeneration of hepatocytes
  • glycogen infiltration of Henna stitches

Pregunta 46

Pregunta
In the lungs in heamatogenous way most commonly metastasize:
Respuesta
  • glioblastoma multiform
  • sarcomas
  • uterine cancer
  • kidney cancer

Pregunta 47

Pregunta
Which of the following tumors most often metastasise in the bones:
Respuesta
  • liposarcoma
  • osteosarcoma
  • prostate cancer
  • breast cancer

Pregunta 48

Pregunta
It is true that:
Respuesta
  • benign tumors have only a cellular atypia, and malignant tumors have cellular and tissue atypia
  • cellular atypia includes polymorphism polihromasis, hiperhromasis
  • woven atypia includes monomorphic, metachromasia and chromoforms
  • cytological examination is very useful in benign tumors

Pregunta 49

Pregunta
Which tumor has not own stroma, and its cells are fed by bleedings caused by infiltrative process?
Respuesta
  • small cell lung carcinoma
  • choriocarcinoma
  • papillary thyroid carcinoma
  • malignant melanoma

Pregunta 50

Pregunta
Which of these features are inherent in benign tumors?
Respuesta
  • tissue atypia
  • cell atypia
  • pseudocapsule
  • expansive growth

Pregunta 51

Pregunta
How metastasize carcinoma in situ?
Respuesta
  • Lymphogenic
  • Perineurial
  • Hematogenic
  • Does not metastasize

Pregunta 52

Pregunta
Gliomas metastasize in:
Respuesta
  • Lungs
  • Kidney
  • Bone structure
  • Central nervous system

Pregunta 53

Pregunta
Ulcos Rodens is a metaphor for macroscopic finding in:
Respuesta
  • adenocarcinoma of the stomach
  • rodent bites
  • chronic gastric ulcer
  • basal cell carcinoma

Pregunta 54

Pregunta
Which tumors are malignant?
Respuesta
  • glioblastoma
  • lymphoma
  • melanoma
  • seminoma

Pregunta 55

Pregunta
Sarcomas are characteristic of:
Respuesta
  • parenchymal cells are diffuse located
  • metastasize in lymph way
  • early organ metastases are in the lungs
  • they are most common in the early age

Pregunta 56

Pregunta
Which of these malignant tumors metastasize in the kidney?
Respuesta
  • Lung carcinoma
  • Osteosarcoma
  • Gastric cancer
  • Bladder carcinoma

Pregunta 57

Pregunta
Specify the characteristics of benign tumors?
Respuesta
  • They grow slowly but expansively
  • Infiltrate and damage tissues and organs
  • They are not separated well from the other tissues
  • parenchyma cells showed no atypicallity

Pregunta 58

Pregunta
Hereditary tumors are:
Respuesta
  • carcinoma of the endometrium
  • polyposis of the stomach
  • neuroblastoma retinal
  • basal cell carcinoma

Pregunta 59

Pregunta
In expansive growth of tumors was observed:
Respuesta
  • ingrowth of tissue with subsequent destruction
  • invasions becomes along nerve fibers, blood and lymph nodes
  • compression of the surrounding tissues
  • easier separation of the tumor from the surrounding tissue

Pregunta 60

Pregunta
The squamous cell carcinoma can develop from:
Respuesta
  • buccal mucosa
  • bronchial mucosa
  • the lining of vaginal part of the cervix neck
  • epithelium of the gastric mucosa

Pregunta 61

Pregunta
The papilloma:
Respuesta
  • develops primarily in the urinary bladder
  • forms glandular formations
  • contains cancer pearls in its central parts
  • macroscopically viewed it is soft and it has a papillary structure

Pregunta 62

Pregunta
Match correctly the description of an astrocytoma:
Respuesta
  • it originates from the eye retina
  • histologically it consists of small cells arranged in rosettes
  • it develops in the hemispheres of the cerebrum
  • it consists of outgrowth star-shaped cells (fusiform)

Pregunta 63

Pregunta
A malignum melanoma can develop in:
Respuesta
  • the lining of the renal pelvis
  • the choroid of the eye
  • the glandula mammaria (mammary gland)
  • the meninges of the brain (choroid plexus)

Pregunta 64

Pregunta
Dermoid cyst is:
Respuesta
  • mature teratoma, most commonly seen in the ovary
  • benign tumor of the meninges
  • pigmented tumor
  • malignant tumor of the pregnancy

Pregunta 65

Pregunta
Mixed tumor of the parotid gland is:
Respuesta
  • adenoma
  • has bilateral appearance
  • papilloma
  • ulcer

Pregunta 66

Pregunta
Lung cancer metastases most frequently to the:
Respuesta
  • liver
  • bones
  • spleen
  • brain

Pregunta 67

Pregunta
The most typical localisation for the neurilemmoma is:
Respuesta
  • ponto-cerebellar ange
  • falx cerebri
  • tentorium cerebelli
  • cerebellum

Pregunta 68

Pregunta
The presence of plasma cells and lymphocytes in the stroma of the tumors is called:
Respuesta
  • inflammation
  • stromal reaction
  • morphologic anaplasia
  • sinuses histiocytosis

Pregunta 69

Pregunta
The most characteristic features of the neurilemmoma are:
Respuesta
  • arises from peripheral and cranial nerves
  • arises from epithelial cells of the arachnoidea
  • composed of the fibrocellular bundles with palisaded arranged nuclei
  • cells form onion-like structures

Pregunta 70

Pregunta
If the tumor arise again on the same place after previous resection it calls
Respuesta
  • recidive
  • malignant degeneration
  • ectopia
  • metastasis

Pregunta 71

Pregunta
A 72-years old man presented with white spot on the lower lip with slow growth and 1 cm in diameter. Histologically: extensive growth of the squamous epithelium with become keratinizating and underlying chronic inflammatory reaction. The histologic diagnosis is:
Respuesta
  • chronic inflammation
  • leukoplakia
  • adenocarcinoma
  • papilloma

Pregunta 72

Pregunta
A 35-years old woman presented with dark blue to black nodule in anal zone. Histologically tumor consists of the oval and spindle-shape cells with pigmented granules in their cytoplasm which invade dermal and epidermal spases. The diagnosis is:
Respuesta
  • pigmented nevus
  • ephelides
  • malignant melanoma
  • basal cell carcinoma

Pregunta 73

Pregunta
A 43-years old woman presented with abdominal pain and uterine bleeding. Physical examination revealed tumor in the uterine fundus with diameter 5 cm. Grossly tumor is not well-defined soft and whitish. Histologically: spindle-shaped smooth muscle cells having large and hyperchromatic nuclei, areas of necrosis. The diagnosis is:
Respuesta
  • leiomyoma
  • fibroleiomyoma
  • liomyosarcoma
  • fibrosarcoma

Pregunta 74

Pregunta
A 36 years old woman presented with constipation lasting from 6 months, with mucus and blood in stools. Physical examination reveals thickening of the rectal wall 6-7 cm above the anus with narrowing of the lumen. Histologically: diffuse proliferation of the glands which consisted of highly atypical cells. The correct diagnosis is:
Respuesta
  • squamous cell carcinoma
  • adenocarcinoma
  • adenoma
  • sarcoma

Pregunta 75

Pregunta
A 28 years woman has a history of the painless, firm, well-defined nodule in the left breast with diameter 2 cm from year. Histologically: proliferation of the connective tissue around breast duct which are not affected. What Is the correct diagnosis?
Respuesta
  • pericanalicular fibroadenoma
  • intracanaliculat fibroadenoma
  • adenocarcinoma
  • squamous cell carcinoma

Pregunta 76

Pregunta
A 70-years old man has hematuria, from time to time, for 10 months. Lately he started having dysuria. A papillary formation, on a large surface was seen in his urinary bladder. Histologically there are papillary outgrowths of atypical transitional epithelium and infiltration of the deeper layers of the wall of the urinary bladder and the blood vessels. Set the histological diagnosis:
Respuesta
  • squamous cell carcinoma
  • transitional cell carcinoma
  • non-differentiated carcinoma
  • adenocarcinoma

Pregunta 77

Pregunta
In a 35-years old man a solid, well-defined nodule appeared in his right parotid gland, 2cm in diameter. Histological findings: mucus-like tissue, resembling cartilage, among which glandular structures, strands of cuboidal, cylindrical and spindle cells, can be seen. Set the diagnosis:
Respuesta
  • pleomorphic adenoma of the parotid gland
  • adenocarcinoma of the parotid gland
  • myxoma of the parotid gland
  • chondroma of the parotid gland

Pregunta 78

Pregunta
A tumor, 3cm in diameter, well-defined and solid, was surgically removed from the forearm of a 39-years old woman. Histological findings : spindle cells, grouped in bundles with palisade arrangement of the nuclei. Set the histological diagnosis:
Respuesta
  • fibroma
  • leiomyoma
  • myxoma
  • neurinoma

Pregunta 79

Pregunta
On the skin fold between the nose and the right cheek of a 68-years old man there is an ulcer with rigid edges and crater-like base, covered with brownish crusts. Histological findings: nests of round, polygonal and spindle cells, with palisade arrangement at the periphery. Set the diagnosis:
Respuesta
  • basal cell carcinoma
  • squamous cell carcinoma
  • malignant melanoma
  • nevus pigmentosus

Pregunta 80

Pregunta
On the convexity surface of the left hemisphere of the brain, a well-defined tumor, 3cm in diameter, is seen. It has a grayish-brown color and thick density, attached to dura mater. The brain tissue in this area is concave, not infiltrated by the tumor. Set the most probable diagnosis:
Respuesta
  • meningioma
  • astrocytoma
  • neurinoma
  • medulloblastoma
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