Pregunta 1
Pregunta
Indicate the correct statement(s)
Respuesta
-
granulation tissue is rich of capillaries and cells
-
granulation tissue is rich in collagen fibres and fibroblasts and contains less blood vessels
-
granulation tissue is the immature connective tissue
-
fibrous tissue is immature connective tissue
Pregunta 2
Pregunta
What is hyper-granulation?
Pregunta 3
Pregunta 4
Pregunta
What is a keloid?
Pregunta 5
Pregunta
Which stain can be used to prove of scarring (cicatrix) of the heart?
Respuesta
-
Van Gieson
-
Peris
-
Congo Red
-
PAS
Pregunta 6
Pregunta
Which of the could not be seen in rheumatoid nodules?
Respuesta
-
Fibrinoid necrosis
-
Epitheloid cells
-
Langhans cells
-
Lymphocytes
Pregunta 7
Pregunta
Indicate the correct statement(s) for the polyarteriitis nodosa.
Respuesta
-
it is an autoimmune disease
-
it affects mostly the elastic arteries
-
there is accumulation of glucosaminoglycans in the vessel walls which can be demonstrated with metachromasia with Toluidin Bleu
-
the branches of the pulmonary arteries are affected
Pregunta 8
Pregunta
Anaphylactic hypersensitivity reactions are related to:
Respuesta
-
Hemolytic anemia
-
Hashimoto thyroiditis
-
Allergic rhinitis
-
Bronchial asthma
Pregunta 9
Pregunta
Cytotoxic hypersensitivity reactions are related to:
Respuesta
-
hashimoto thyroiditis
-
hemolytic anemia
-
allergic rhinitis
-
nodosal poyarteriitis
Pregunta 10
Pregunta
Immune complexes mediated hypersensitivity reactions are related to:
Respuesta
-
polyartheriitis nodosa
-
rheumatoid arthritis
-
hemolytic anemia
-
tuberculosis
Pregunta 11
Pregunta
Cell mediated hypersensitivity reactions are related to:
Respuesta
-
Tuberculosis
-
Polyarteriitis nodosa
-
Bronchial asthma
-
Hashimoto thyroiditis
Pregunta 12
Pregunta
Indicate characteristics of the benign tumors.
Pregunta 13
Pregunta
Indicate characteristics of the benign tumors
Respuesta
-
infiltrative growth
-
slow, long term developntcnt
-
usually they don't recur after complete surgery
-
their microscopic structure shows only tissue atypia
Pregunta 14
Pregunta
Indicate correct characteristics of the malignant tumors.
Pregunta 15
Pregunta
Indicate correct characteristics of the malignant tumors.
Pregunta 16
Pregunta
Which is the most common way of metastasizing of epithelial tumors?
Pregunta 17
Pregunta
What is papilloma?
Respuesta
-
malignant tumor of the covering epithelium
-
benign tumor of glandular epithelium
-
benign tumor of cover type epithelium
-
benign soft tissue tumor
Pregunta 18
Pregunta
Indicate the correct characteristic(s) for papilloma
Respuesta
-
it has tree-like stroma covered by differentiated stratified squamous epithelium
-
it has tree-like stroma covered by undifferentiated squamous epithelium with signs of cell atypia
-
stroma and parenchyma are difficult to distinguish
-
it doesn't have a capsule
Pregunta 19
Pregunta
What is the term used for malignant tumors of cover type epithelium?
Respuesta
-
adenocarcinoma
-
papilloma
-
carcinoma
-
sarcoma
Pregunta 20
Pregunta
What is the term used for malignant tumors of glandular type epithelial origin?
Respuesta
-
adenocarcinoma
-
adenoma
-
carcinoma
-
carcino-adenoma
Pregunta 21
Pregunta
What is the term used for benign tumors of glandular type epithelial origin?
Respuesta
-
papilloma
-
adenoma
-
teratoma
-
adenocarcinoma
Pregunta 22
Pregunta
Point the correct statement(s) about basal cell carcinoma.
Respuesta
-
it develops only on the skin
-
it can develop at any place with squamous epithelium
-
it characterizes with early lymphogenic and hematogenic metastases
-
very often it recurs at the same place after surgery
Pregunta 23
Pregunta
Keratinized squamous cell carcinoma:
Respuesta
-
develops only on the skin
-
can develop at any place with squamous epithelium
-
is highly undifferenciated malignant tumor
-
is a tumor composed of more differenciated cells with keratin production
Pregunta 24
Pregunta
What kind of structures are the cancer perls?
Respuesta
-
accumulation of keratin produced by more differentiated malignant cells originating from squamous epithelium
-
pink-coloured homogenous substance located in the centre of the tumor nests
-
accumulation of mucus produced by highly undifferentiated malignant cells located in the centre of the tumor nests
-
pink homogenous substance that accumulates in the stroma of the tumor
Pregunta 25
Pregunta
The gross appearance of which tumor is called "ulcus rodens"?
Respuesta
-
squamous cell carcinoma
-
melanoma
-
basal cell carcinoma
-
adenocarcinoma
Pregunta 26
Pregunta
Squamous cell carcinoma develops in the lung after:
Pregunta 27
Pregunta
Indicate the correct microscopic features of cell atypia
Respuesta
-
polymorphism of cells and nuclei
-
low nucleus-cytoplasm index
-
typical mitoses
-
monster cells, hyperchromasia and polychromasia of nuclei
Pregunta 28
Pregunta
What are the characteristics of the nuclei of the malignant tumors?
Pregunta 29
Pregunta
Papillary carcinoma of the urinary bladder arises from:
Respuesta
-
squamous epithelium
-
transitional epithelium
-
glandular epithelium
-
smooth musculature
Pregunta 30
Pregunta
What is carcinoma in situ?
Respuesta
-
malignant tumor limited to the epithelium above the basal membrane
-
malignant tumor destroying the basal membrane but spreading no more than 5mm below it
-
benign tumor limited to the basal membrane
-
benign tumor of a great size compressing the surrounding tissues
Pregunta 31
Pregunta
What type of atypia could be seen in the benign tumors of glandular epithelium?
Pregunta 32
Pregunta
Which staining is used for proving mucus production from gelatinous adenocarcinoma?
Pregunta 33
Pregunta
Pericanalicular and intracanalicular are types of:
Pregunta 34
Pregunta
Kruckenberg tumors are:
Respuesta
-
metastases from colon adenocarcinoma in the ovaries
-
metastases from pancreatic adenocarcinoma in the ovaries
-
metastases from gastric carcinoma in the ovaries
-
metastases from hepatocellular carcinoma in the ovaries
Pregunta 35
Pregunta
Pleomorphic adenoma could be seen mainly:
Pregunta 36
Pregunta
Indicate the correct statements about fibroadenoma of the breast.
Respuesta
-
capsulated and lobulated tumor
-
non-capsulated malignant tumor with invasive growth
-
microscopically it has two types -- intracanalicular and pericanalicuJar
-
seen in older women
Pregunta 37
Pregunta
Mark the correct statements about papillary cystadenoma of the ovary:
Respuesta
-
malignant tumor
-
has cyst-like and papillary structures
-
histological characteristics include serous and mucinous types
-
it is a physiological change related to menstrual cycle
Pregunta 38
Pregunta
'Linitis plastica' is a gross subtype of:
Respuesta
-
gastric cancer
-
pancreatic cancer
-
breast cancer
-
uterine cancer
Pregunta 39
Pregunta
Grossly adenocarcinoma of the colon can be:
Respuesta
-
polypoid
-
ulcerous
-
nodular
-
all of the listed above
Pregunta 40
Pregunta
The terms "early cancer" and "advanced cancer" are used for:
Pregunta 41
Pregunta
Malignant tumors from soft tissue are called:
Pregunta 42
Pregunta
Indicate the characteristics of the sarcomas.
Respuesta
-
seen in older age
-
grossly they look like "fish meat"
-
they give early hematogenic metastases
-
parenchyma and stroma are equally distributed
Pregunta 43
Pregunta
Mark the characteristics of the carcinomas.
Respuesta
-
seen in young people
-
they metastasize by the blood flow first
-
grossly they have granular surface
-
parenchyma and stroma are equally distributed
Pregunta 44
Pregunta
What kind of sarcoma could be seen in an immune deficiency?
Respuesta
-
Kaposi sarcoma
-
Ewing sarcoma
-
Rhabdomyosarcoma
-
Chondrosarcoma
Pregunta 45
Pregunta
Which of the following sarcomas have the worst prognosis?
Respuesta
-
liposarcoma
-
ostesarcoma
-
fibrosarcoma
-
leiomysarcoma
Pregunta 46
Pregunta
What staining can be used to distinguish leiomyoma uteri from fibroma?
Pregunta 47
Pregunta
Point the characteristics of the leiomyosarcoma.
Pregunta 48
Pregunta
What is hybernoma?
Respuesta
-
benign tumor of vascular origin
-
benign tumor originating from brown fat tissue
-
benign tumor originating from striated muscles
-
malignant tumor originating from pigment tissue
Pregunta 49
Pregunta
What are the signs of the atypia in a nevus?
Respuesta
-
asymmetry of the lesion, irregular borders
-
dark color, irregular color of the lesion
-
diameter less than 5mm
-
regular borders
Pregunta 50
Pregunta
How should a biopsy be done if there is a suspicion for the melanoma?
Respuesta
-
incision biopsy
-
punch biopsy
-
excision biopsy
-
brush biopsy
Pregunta 51
Pregunta
Point the most common localizations of the teratomas.
Respuesta
-
ovaries, testis
-
extremities
-
retroperitoneum
-
mediastinum
Pregunta 52
Pregunta
Which of the following are organoid teratomas
Respuesta
-
nephroblastoma
-
cholesteatoma
-
dermoid cyst
-
branchiogcnic cyst
Pregunta 53
Pregunta
Which of the following is organismoid teratoma
Respuesta
-
epidermoid cyst
-
teratocarcinoma
-
dermoid cyst
-
nefroblastoma
Pregunta 54
Pregunta
What is a nevus pigmentosus?
Pregunta 55
Pregunta
What is a melanoma?
Respuesta
-
malignant congenital tumor
-
benign tumor composed of melanocytes
-
malignant tumor of pigment origin
-
none of the above
Pregunta 56
Pregunta
What is an achromatic melanoma?
Respuesta
-
benign form of melanoma
-
melanoma without melanin in the tumor cells
-
type of melanoma which can be proved with immunohistochemical tests
-
melanoma which is more differentiated
Pregunta 57
Pregunta
Point possible localizations of the nevus pigmentosus and melanoma.
Respuesta
-
skin
-
uvea
-
meninges
-
all of the above
Pregunta 58
Pregunta
Lentigo maligna, nodular, superficial, acral lentigenous are gross forms of:
Pregunta 59
Pregunta
Indicate immunohistochemical stains to prove melanoma
Respuesta
-
HMB-45
-
Ca-125
-
S-100
-
Cytokeratin
Pregunta 60
Pregunta
Which of the following tumors do not have a stroma
Respuesta
-
choriocarcinoma
-
seminoma
-
nephroblstoma
-
neuroblastoma
Pregunta 61
Pregunta
Indicate types of nevus pigmentosus:
Respuesta
-
acquired and congenital
-
junctional, compound, intradermal
-
benign and malignant nevus
-
ectodermal and endodermal nevus
Pregunta 62
Respuesta
-
lipidogenic pigment
-
proteinogenic pigment
Pregunta 63
Pregunta
Where is lipofuscin deposited?
Respuesta
-
intracellularly
-
extracellularly
Pregunta 64
Pregunta
The frozen section ('gefrir') is:
Pregunta 65
Pregunta
The term „pathognomonic change" means:
Pregunta 66
Pregunta
Most likely the cause of centrolobular fatty degeneration of hepatocytes is:
Respuesta
-
diabetes
-
intoxication
-
hypoxia
-
overfeeding
Pregunta 67
Pregunta
Hyaline — droplet degeneration has following characteristics:
Pregunta 68
Pregunta
What pigment is formed in the center of the hematoma?
Respuesta
-
hemosiderin
-
lipofuscin
-
hemomelanin
-
hematoidin
Pregunta 69
Pregunta
In which blood vessels are formed most frequently mixed thrombi?
Respuesta
-
large veins
-
arteries
-
capillaries
-
venules
Pregunta 70
Pregunta
Squamous cell carcinoma occurs most frequently in:
Respuesta
-
stomach
-
skin
-
bladder
-
larynx
Pregunta 71
Pregunta
Hyperemic-hemorrhagic zone occurs in:
Respuesta
-
tophi urici
-
nodular amyloidosis
-
anemic infarction
-
pneumonia
Pregunta 72
Pregunta
Which types of bleeding occur in the digestive system?
Respuesta
-
hemothorax
-
hemoptysis
-
melena
-
hematemesis
Pregunta 73
Pregunta
Which of the following cell damages are irreversible?
Respuesta
-
necrosis
-
apoptosis
-
vacuolar degeneration
-
cellular edema
Pregunta 74
Pregunta
Left ventricular hypertrophy can develop in:
Respuesta
-
cor pulmonale
-
systemic hypertension
-
mitral stenosis
-
aortic stenosis
Pregunta 75
Pregunta
Cancer cells which show no resemblance to the tissue from which the tun originates are called:
Pregunta 76
Pregunta
Which of the following is correct for the mechanical jaundice?
Respuesta
-
indirect bilirubin prevails in blood
-
elevated urine urobilinogen
-
elevated urine bilirubin
-
stools are hyperpigmented
Pregunta 77
Pregunta
Basal cell carcinoma is localized most frequently on:
Pregunta 78
Pregunta
Caseous necrosis is characteristic for:
Respuesta
-
specific inflammation
-
tuberculosis
-
enzyme fat necrosis
-
chronic pyelonephritis
Pregunta 79
Pregunta
Bilaterally, on the skin of the eyelids of a young woman are seen yellow nodules with the size of a grain of rice. What is it?
Respuesta
-
xanthelasmas
-
nevus
-
efelides
-
hemosiderin deposition
Pregunta 80
Pregunta
Which of the following are protein accumulations?
Pregunta 81
Pregunta
Hemorrhagic infarction develops in:
Pregunta 82
Pregunta
How do we call the local depigmentation of the skin?
Respuesta
-
vitiligo
-
hemosiderosis
-
albinism
-
ohronosis
Pregunta 83
Pregunta
What kinds of techniques are used for the detection of the lipids:
Respuesta
-
freezing microtome
-
paraffin method
-
alcohol fixation
-
staining with Sudan Ill
Pregunta 84
Pregunta
The sequence of local structural changes in a disease is called
Respuesta
-
sanogenesis
-
pathogenesis
-
tanatogenesis
-
morphogenesis
Pregunta 85
Pregunta
" Tiger Heart " is diagnosed when:
Respuesta
-
subepicardial fat is increased
-
yellowish lines in the papillary muscles are seen
-
the interventricular septum is injured
-
infarcted area of the left ventricle in seen
Pregunta 86
Pregunta
Which of the following is correct for the mechanical jaundice:
Respuesta
-
it is parenchymal jaundice
-
there is posthepatic occlusion
-
direct bilirubin is increased
-
it is also called hemolytic jaundice
Pregunta 87
Pregunta
The risks involved in fast draining of large quantities of acistes are:
Respuesta
-
development of low oncotic pressure edema
-
bleeding into the abdominal cavity
-
massive arterial hyperemia in the abdominal vessels
-
hemodynamic collapse
Pregunta 88
Pregunta
"Mutilation" means :
Respuesta
-
form of biological mutation
-
pendulum movement of the blood
-
zonal hair loss
-
self amputation of phalanges
Pregunta 89
Pregunta
It is true that :
Respuesta
-
concentric hypertrophy is also called tonogenic
-
eccentric hypertrophy is myogenic
-
hypertrophy can be combined with hyperplasia
-
false type of hypertrophy is hyperplasia
Pregunta 90
Pregunta
Sources of fat embolism in the lung are
Respuesta
-
the bone marrow in the long bones
-
subcutaneous fat
-
liver with fatty degeneration
-
ulcerated atherosclerotic plaque of the aorta
Pregunta 91
Pregunta
Which of these factors lead to nutmeg liver?
Pregunta 92
Pregunta
In the bronchi and nasal cavity may develop squamous cell carcinoma based on:
Pregunta 93
Pregunta
Amyloid demonstates following characteristics:
Respuesta
-
identified with Tioflavin S in fluorescence
-
shows metachromasia with Perls
-
identified with Congo rot in polarized light
-
ultrastructurally has fibrillary structure
Pregunta 94
Pregunta
Anaphylactic shock occurs in:
Respuesta
-
hypersensitivity reactions cytotoxic type
-
response induced by immune complexes
-
atopic reactions
-
delayed type hypersensitivity
Pregunta 95
Pregunta
A basal cell carcinoma is localized most frequently on:
Pregunta 96
Pregunta
Reaction for Prussian blue is used for:
Respuesta
-
tattoos
-
proof of bilirubin
-
proof of hemosiderin
-
in hemochromatosis
Pregunta 97
Pregunta
How could an air embolism be proved:
Respuesta
-
in the presence of witnesses
-
autopsy in a bathtub
-
puncturing the right ventricle
-
puncturing of the left ventricle
Pregunta 98
Pregunta
Which enzymes are involved in a melanogenesis?
Respuesta
-
hyaluronidase
-
tvrosinase
-
dopa oxidase
-
lipase
Pregunta 99
Pregunta
Infarctions of which organs could often lead to the death of the patient?
Respuesta
-
renal infarction
-
infarction of the spleen
-
infarction of heart
-
cerebral infarction
Pregunta 100
Pregunta
In cancers with epithelial origin: