Clinical Pathoanatomy MCQs (Q 151-250)

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Quiz on MCQs in Clinical Pathology - 4th year PMU (Q 151-250), created by Ore iyanda on 16/01/2018.
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Pregunta 1

Pregunta
The most frequent form of primary glomerular disease in children is
Respuesta
  • Minimal change disease
  • Acute glomeruonephritis

Pregunta 2

Pregunta
Hyperfunction of anterior pituitary in pre-pubertal children generally can result in
Respuesta
  • Acromegaly
  • Gigantism

Pregunta 3

Pregunta
The role of external radiation in the etiology of thyroid cancer is predominant in
Respuesta
  • Papillary carcinoma
  • Follicular carcinoma

Pregunta 4

Pregunta
The following type of carcinoma of the breast is characterised by 'Indian file' pattern of tumour cells
Respuesta
  • Infiltrating distal carcinoma
  • Invasive lobular carcinoma

Pregunta 5

Pregunta
Prostatic hyperplasia affects most often
Respuesta
  • Peripheral prostate
  • Periurethral prostate

Pregunta 6

Pregunta
Which criteria refer to pernicious anaemia
Respuesta
  • Low serum B12
  • Megaloblastic anaemia
  • Antibody against internal factor of Castle
  • Gastric parietal cell antibody

Pregunta 7

Pregunta
Which of the following tumours have association with occupational exposure to asbestosis?
Respuesta
  • Silicosis
  • Malignant mesothelioma
  • Squamous cell carcinoma
  • Laryngeal carcinoma

Pregunta 8

Pregunta
Which of the following features characterise ulcerative colitis, except
Respuesta
  • Formation of crypt abscess and cryptitis
  • Superficial mucosal ulceration
  • Depletion of goblet cells and mucus
  • Stricture formation in chronic cases

Pregunta 9

Pregunta
Philadelphia chromosome is characterised by
Respuesta
  • Translocation (8;14)
  • Translocation (9;22)
  • Translocation (22;9)
  • Translocation (14;8)

Pregunta 10

Pregunta
Which of the following are included in classic Hodgkin's disease
Respuesta
  • Histiocytic fibrosis
  • Lymphocytic depletion
  • Mixed cellularity
  • Nodular sclerosis

Pregunta 11

Pregunta
Pulseless disease is
Respuesta
  • Temporal arteritis
  • Kawasaki's disease
  • Takayasu arteritis
  • Buerger's disease

Pregunta 12

Pregunta
The morphological variants of diagnostic cells in Hodgkin's disease are
Respuesta
  • Cells with bilobed nucleus appearing as mirror image
  • Megaloblastic cells
  • Lacunar type cell
  • Large cleaved cells

Pregunta 13

Pregunta
Crohn's disease is characterised by the following histopathologic features
Respuesta
  • Non-caseating sarcoid like granulomas
  • Deep transmural ulceration
  • Multiple abscesses
  • Pseudopolyps

Pregunta 14

Pregunta
According to monoclonal atherosclerosis hypothesis, the primary event in atherosclerosis is
Respuesta
  • Monoclonal proliferation of endothelial cells
  • Monoclonal proliferation of smooth muscle cells
  • Monoclonal proliferation of monocytes
  • Monoclonal proliferation of foam cells

Pregunta 15

Pregunta
Barrett's oesophagus is
Respuesta
  • Congenital anomaly
  • Inflammatory disease
  • Metaplastic process
  • Neoplastic lesion

Pregunta 16

Pregunta
The most common site of involvement of atherosclerosis aneurysm is
Respuesta
  • Arch of aorta
  • Thoracic aorta
  • Suprarenal part of abdominal aorta
  • Infrarenal part of abdominal aorta

Pregunta 17

Pregunta
The following histologic types of bronchogenic carcinoma have strong association with cigarette smoking except
Respuesta
  • Squamous cell carcinoma
  • Small cell carcinoma
  • Large cell carcinoma
  • Adenocarcinoma

Pregunta 18

Pregunta
The most important and common complicated atheromatous lesion in the coronary artery in acute myocardial infarction is
Respuesta
  • Calcification
  • Coronary artery thrombosis
  • Aneurysm
  • Ulceration

Pregunta 19

Pregunta
In hypertensive heart disease left ventricular hypertrophy is correlated with
Respuesta
  • Duration of hypertension
  • Severity of hypertension
  • Cause of hypertension
  • Severity of coronary atherosclerosis

Pregunta 20

Pregunta
The most common causative agent for lobar pneumonia is
Respuesta
  • Staphylococci
  • Streptococci
  • Pneumococci
  • Haemophilus

Pregunta 21

Pregunta
The common complications of gastric ulcer are
Respuesta
  • Penetration
  • Pneumonia
  • Haemorrhage
  • Perforation

Pregunta 22

Pregunta
What complication can occur due to atherosclerosis of femoral artery?
Respuesta
  • Thrombophlebitis
  • Diabetes mellitus
  • Gangrene
  • Pulmonary thromboembolism

Pregunta 23

Pregunta
Which of the following types of acute viral hepatitis become chronic hepatitis?
Respuesta
  • Type A
  • Type B
  • Type C
  • All the three answers are correct

Pregunta 24

Pregunta
Nephrotic syndrome develops in
Respuesta
  • Urine retention
  • Acute renal failure
  • Acute pyelonephritis
  • Glomerulonephritis

Pregunta 25

Pregunta
The infection which leads to pyelonephritis may be a result of
Respuesta
  • Hematogenous dissemination
  • Ascending dissemination
  • Immune conflict
  • As a complication of glomerulonephritis

Pregunta 26

Pregunta
Which of the following diseases does not lead to nephrosclerosis?
Respuesta
  • Atherosclerosis
  • Diabetes mellitus
  • Diabetes insipidus
  • Gout

Pregunta 27

Pregunta
Squamous cell carcinoma is a common tumour in the
Respuesta
  • Uterine body
  • Ovaries
  • Fallopian tubes
  • Uterine cervix

Pregunta 28

Pregunta
Which of the morphological methods are used for subtyping lymphomas?
Respuesta
  • Van Gieson staining
  • PAS
  • Von Kossa staining
  • Immunohistochemistry

Pregunta 29

Pregunta
Which of the following complications can develop in pulmonary carcinoma?
Respuesta
  • Mantle pneumonia
  • Brown induration of lungs
  • Empyema
  • Massive haemorrhage

Pregunta 30

Pregunta
Determine the pathological process in the lung emphysema, having in mind the microscopic appearance - a focus of necrosis, detritus, leukocytes and macrophages
Respuesta
  • Acute pulmonary abscess
  • Chronic pulmonary abscess
  • Bronchiectasis
  • Lung cancer in decay

Pregunta 31

Pregunta
What disease is endometriosis?
Respuesta
  • Inflammation of the uterine mucosa
  • Inflammation of the uterine cervix
  • Dishormonal disease
  • Tumour

Pregunta 32

Pregunta
Point out the characteristic macroscopic changes of chronic obstructive emphysema
Respuesta
  • Decreased in size lungs, collapsed to the hilum
  • Lungs with increased volume
  • Thick consistency of the lungs
  • Reduced elasticity and soft consistency

Pregunta 33

Pregunta
Gynecomastia is a disease of
Respuesta
  • Breast in women
  • Ovaries
  • Male breast
  • Testes

Pregunta 34

Pregunta
What is typical for the first stage of syphilis?
Respuesta
  • Siphilides
  • Ulcus durum
  • Gumma
  • Generalised lymphadenitis

Pregunta 35

Pregunta
For tuberculous meningitis the following histological changes are typical
Respuesta
  • Purulent infiltration in the meninges
  • Endarteriitis obliterans
  • Granulomatous inflammation
  • Caseous necrosis

Pregunta 36

Pregunta
Why are occupational diseases named pneumoconiosis?
Respuesta
  • Cor hypertonicum
  • Disease of the lungs associated with mineral dust inhalation
  • Pneumonia
  • Infection of the bronchial wall and lung parenchyma

Pregunta 37

Pregunta
Which of the following factors play a role in the development of bronchial carcinoma?
Respuesta
  • Chronic bronchitis
  • Smoking
  • Influenza
  • Work/environmental factors

Pregunta 38

Pregunta
What is the exudate in the pleural cavity and pericardial sac due to lymphatic spread of pulmonary carcinoma into them?
Respuesta
  • Fibrinous
  • Serious
  • Haemorrhagic
  • Purulent

Pregunta 39

Pregunta
What forms of silicosis do you know?
Respuesta
  • Nodular
  • Diffuse-sclerotic
  • Senile
  • Combination of a and b (Nodular & Diffuse-sclerotic)

Pregunta 40

Pregunta
Apically located peripheral pulmonary carcinoma is represented by the eponym
Respuesta
  • Claude-Bernard-Horner syndrome
  • Pancoast-Tobias
  • Ptosis and miosis
  • Enophthalmus

Pregunta 41

Pregunta
Which diseases complicate silicosis?
Respuesta
  • Cor hypertonicum
  • Cor pulmonale chronicum
  • Tuberculosis
  • Pneumofibrosis

Pregunta 42

Pregunta
Claude-Bernard-Horner syndrome includes the following
Respuesta
  • Ptosis, midriasis, anhydrosis
  • Ptosis, miosis, increased sweating
  • Ptosis, miosis, pseudoenophthalmus
  • Anhydrosis

Pregunta 43

Pregunta
What possible gross changes do we see in lung carcinoma?
Respuesta
  • Pneumonia-like form
  • ill-defined central node connected to a bronchus
  • Linitis plastic
  • Peripheral ill-defined node

Pregunta 44

Pregunta
Chronic bronchitis is usually accompanied by
Respuesta
  • Squamous cell metaplasia of the respiratory epithelium
  • Phases of purulent inflammation
  • Productive cough for at least 2 months/year for 3 consecutive years
  • Productive cough for at least 3 months/year for 2 consecutive years

Pregunta 45

Pregunta
Squamous cell lung carcinoma occurs
Respuesta
  • In the middle lobe of the left lung
  • After squamous cell metaplasia of the respiratory epithelium of bronchi
  • As an ill-defined node connected to a bronchus
  • Forming nests of Tumour cells producing keratin

Pregunta 46

Pregunta
In small cell lung carcinoma we can observe
Respuesta
  • Numerous Tumour cells with scant stroma
  • The tumour cells resemble oat-grains
  • It grows in a pneumonia-like fashion
  • The tumour cells have very high proliferative rate

Pregunta 47

Pregunta
Bronchio-alveolar pulmonary carcinoma is characterised by
Respuesta
  • Forms papillary folds into the alveolar lumen
  • It is a form of squamous cell carcinoma
  • The cells produce keratin
  • It is a form of adenocarcinoma

Pregunta 48

Pregunta
Hodgkin lymphoma has
Respuesta
  • Five histological variants
  • Hodgkin cells
  • Reed-Sternberg cells
  • Polyclonal inflammatory background

Pregunta 49

Pregunta
In Hodgkin lymphoma we can observe
Respuesta
  • Effaced lymph node structure
  • Nodular sclerosis histological form
  • Mixed cellularity histological form
  • Chronic myeloleukemia

Pregunta 50

Pregunta
Non-Hodgkin lymphomas can be
Respuesta
  • Nodal
  • B-cell and T-cell types
  • Extranodal
  • None of the above

Pregunta 51

Pregunta
In chronic lympholeukemia in the liver can be seen
Respuesta
  • Myeloblasts
  • Mature lymphocytes and single lymphoblasts
  • Focal leukemic infiltrates in the portal spaces
  • Leukemic infiltrates in the sinusoids

Pregunta 52

Pregunta
Chronic myeloleukemia causes the following changes in liver
Respuesta
  • Effaced lobular structure
  • Hypertrophy and hyperplasia of hepatocytes
  • Atrophy of hepatocytes
  • Leukaemic infiltrates in the sinusoids

Pregunta 53

Pregunta
In chronic myeloleukemia we observe the following
Respuesta
  • Long remissions even without treatment
  • Extreme hepato-splenomegaly
  • Anemia, hemorrhages, infections
  • Splenic infarctions

Pregunta 54

Pregunta
Which are the clinical phases of chronic myeloleukemia?
Respuesta
  • Chronic stable phase
  • Accelerated phase
  • Blast crisis
  • None of the above

Pregunta 55

Pregunta
In Hodgkin lymphoma, mixed cellularity type
Respuesta
  • There can be seen numerous eosinophils
  • We can observe area with necrosis
  • Intact histological lymph nose structure
  • Giant bi-uncleared cells, called 'mirror image'

Pregunta 56

Pregunta
Plasmocytoma has the following features
Respuesta
  • Reed-Sternberg Tumour cells
  • Jelly-like raspberry red osteolytic bone lesion
  • The tumour cells have a large vacuolar nucleus with prominent nucleolus
  • The tumour cells have a round eccentric nucleus with a pale halo around it

Pregunta 57

Pregunta
Which of the following are examples of pathological processes in the oral cavity that can have an effect of internal organs?
Respuesta
  • Scarlet fever
  • Peritonsilar abscess
  • Epilus
  • Oral squamous cell carcinoma

Pregunta 58

Pregunta
Which avitaminoses can be associated with changes in the oral cavity?
Respuesta
  • Vit. B6
  • Vit. B12
  • Vit. D
  • None of the above

Pregunta 59

Pregunta
Vitamin B12 deficiency can cause the following changes in the oral cavity
Respuesta
  • Glossomegaly
  • Hunter's tongue (atrophic gastritis)
  • Geographic tongue
  • Fibrinous gingivitis

Pregunta 60

Pregunta
What type of examination will you suggest to your patient if you diagnose him/her with atrophic glossitis (Hunter's tongue)?
Respuesta
  • Colonoscopy
  • Dermatoscopy
  • Gastroscopy
  • Hysteroscopy

Pregunta 61

Pregunta
If a patient with atrophic glossitis is examined with gastroscopy, what can be the findings in gastric mucosa?
Respuesta
  • Menetrier's disease
  • Atrophic autoimmune gastritis
  • Acute fibrinous gastritis
  • None of the above

Pregunta 62

Pregunta
The risk of which disease does atrophic autoimmune gastritis carry?
Respuesta
  • Acute gastritis
  • Atrophy of the colonic mucosa
  • Rectal cancer
  • Gastric cancer

Pregunta 63

Pregunta
What are the usual changes in leukoplakia?
Respuesta
  • The epithelium is hyperkeratotic
  • Acanthosis in the epithelium
  • Chronic inflammation
  • Dysplasia in the epithelium can be observed

Pregunta 64

Pregunta
What can we observe in leukoplakia?
Respuesta
  • Parakeratosis
  • Dysplasia
  • Carcinoma in situ
  • Diabetes

Pregunta 65

Pregunta
Which of the following is true of pleomorphic adenoma of the parotid gland
Respuesta
  • It is a benign tumour
  • It contains hyperplastic fatty tissue
  • It is firm and Lobulated
  • It is painful and inflamed

Pregunta 66

Pregunta
In chronic tonsillitis we can observe the following
Respuesta
  • Purulent exudate
  • Hypertrophic tonsillitis
  • Atrophic tonsillitis
  • It is a predisposing factor for the formation of epilus

Pregunta 67

Pregunta
The typical histological picture of epilus includes
Respuesta
  • Langhans giant multinuclear cells
  • Fresh haemorrhages and hemosiderin
  • Osteoclast-type multinuclear giant cells
  • It is a true tumour

Pregunta 68

Pregunta
Adamantinoma (amelloblastoma) is
Respuesta
  • A true tumour
  • An odontogenic tumour
  • When compressed the sound is described as flapping wings
  • When it is compressed the sound is described as eggshell cracking

Pregunta 69

Pregunta
Why is it necessary to comment on the presence or absence of H.pylori in gastric biopsies?
Respuesta
  • H.pylori is a risk factor for MALT lymphoma
  • H.pylori is a risk factor for duodenal cancer
  • H.pylori causes chronic gastritis
  • H.pylori is a severe fungal infection

Pregunta 70

Pregunta
Which of the following are possible complications of chronic gastric ulcer?
Respuesta
  • Penetration in the diaphragm
  • Perforation
  • Pyloric stenosis
  • Massive haemorrhage

Pregunta 71

Pregunta
Which special stain help us determine the presence of H.pylori in gastric biopsies?
Respuesta
  • Van Gieson
  • Giemsa
  • Congo Red
  • Immunohistochemistry

Pregunta 72

Pregunta
The following changes can be observed in acute duodenal ulcer
Respuesta
  • Fibrinoid necrosis at the ulcer base
  • Inflammatory infiltrate with lymphocytes and plasma cells
  • Ulceration penetrating through muscularis mucosae, reaching muscularis propria
  • It often undergoes malignant transformation

Pregunta 73

Pregunta
What histological types of gastric cancer do you recognise?
Respuesta
  • Adenocarcinoma
  • Signet-ring cell carcinoma
  • Squamous cell carcinoma
  • Mucinous adenocarcinoma

Pregunta 74

Pregunta
In phlegmonous appendicitis we can observe the following
Respuesta
  • Peri-appendicitis
  • Lymphocyte infiltration in the mucosa
  • Neutrophilic infiltration throughout the thickness of the wall of the appendix
  • Constriction of the blood vessels of the serosa

Pregunta 75

Pregunta
Phlegmonous appendicitis is characterised by
Respuesta
  • Purulent exudate in the lumen
  • Hypoplasia of the lymph follicles
  • Hyperplastic activated lymph follicles
  • Hyperemic blood vessels of the serosa

Pregunta 76

Pregunta
Gangrenous appendicitis is characterised by
Respuesta
  • Lymphocytic infiltration of the mucosa
  • Thrombosis of blood vessels
  • Necrosis of the wall of the appendix
  • Severe inflammation through the wall of the appendix

Pregunta 77

Pregunta
What are the causes which may lead to micro-nodular liver cirrhosis?
Respuesta
  • Acute viral hepatitis
  • Chronic viral hepatitis
  • Cardiogenic shock
  • Chronic alcoholism

Pregunta 78

Pregunta
Which of the types of necrosis are found in chronic active hepatitis?
Respuesta
  • Piece-meal necrosis
  • Adjacent necrosis
  • Bridging necrosis
  • Caseous necrosis

Pregunta 79

Pregunta
Why does the level of calcium in the blood has prognostic value in acute pancreatitis?
Respuesta
  • Calcium is deposited in the bones
  • Calcium levels in the blood slower with the progression of steato-necrosis
  • Calcium reacts with fatty acids to form soaps
  • It has no prognostic value

Pregunta 80

Pregunta
Some of the gross features of acute pancreatitis are
Respuesta
  • Enlarged liver
  • Steatonecrosis of the fatty tissue around and inside the pancreas
  • Haemorrhages in the tissues of the pancreas
  • Fibrosis in the tissues of the pancreas

Pregunta 81

Pregunta
What histological changes can be observed in chronic hepatitis?
Respuesta
  • Chronic cholecystitis
  • Inflammatory infiltrates
  • Massive necrosis of hepatocytes
  • Fibrotic septa

Pregunta 82

Pregunta
Chronic cholecystitis is characterised by the following
Respuesta
  • Often it is accompanied by cholelithiasis
  • It has no association with cholelithiasis
  • Can cause adhesions
  • It is caused by viral infection

Pregunta 83

Pregunta
Which is the following can be complications caused by chronic cholecystitis?
Respuesta
  • Peritonitis
  • Obstruction of d.choledochus
  • Cholestasis
  • Pancreatitis

Pregunta 84

Pregunta
After consuming poisonous mushrooms, a patient shows signs of acute liver failure with progressive reduction of the size of the liver. What process has developed in the liver?
Respuesta
  • Acute viral hepatitis
  • Massive hepatic necrosis
  • Hepatocellular carcinoma
  • None of the above

Pregunta 85

Pregunta
After consuming poisonous mushrooms, a patient shows signs of acute liver failure with progressive reduction of the size of the liver. Besides liver failure, what other complication can worsen the patient's clinical condition?
Respuesta
  • Left sided heart failure
  • Right sided heart failure
  • Pyelonephritis
  • Acute renal failure

Pregunta 86

Pregunta
Which of the following can occur after a streptococcal tonsillitis?
Respuesta
  • Post-infectious cholecystitis
  • Post-infectious glomerulonephritis
  • Minimal change disease of the kidneys
  • Acute rheumatism

Pregunta 87

Pregunta
Which types of glomerulonephritis are clinically presented by nephritic syndrome?
Respuesta
  • Diffuse endocapillary glomerulonephritis
  • Rapidly progressing glomerulonephritis
  • Minimal change disease
  • Membranous glomerulonephritis

Pregunta 88

Pregunta
Which types of glomerulonephritis are clinically presented by nephrotic syndrome?
Respuesta
  • Diffuse endocapillary glomerulonephritis
  • Rapidly progressing glomerulonephritis
  • Minimal change disease
  • Membranous glomerulonephritis

Pregunta 89

Pregunta
What findings can be observed in glomerulonephritis?
Respuesta
  • Klebsiella
  • E.coli
  • Streptococcus
  • The urine is sterile

Pregunta 90

Pregunta
Which type of glomerulonephritis is 'crescentic'?
Respuesta
  • Minimal change disease
  • Rapidly progressing glomerulonephritis
  • Membranous glomerulonephritis
  • Diffuse endocapillary glomerulonephritis

Pregunta 91

Pregunta
'Big white kidney' can be observed in the following cades
Respuesta
  • Rapidly progressing glomerulonephritis
  • Amyloidosis of the kidney
  • Minimal change disease
  • Nephrosclerotic glomerulonephritis

Pregunta 92

Pregunta
Which of the following histological changes are associated with tubal pregnancy?
Respuesta
  • Chorionic Villi and decidual Changes of the endometrium
  • Monstrous trophoblast, hydropic chorionic villi
  • Hematoma in Fallopian tube, chorionic villi invading the muscular layer of the tube, decidual changes of the endometrium
  • Cervical intraepithelial lesion, third grade

Pregunta 93

Pregunta
Which of the following histological changes are associated with mola hydatidosa?
Respuesta
  • Chorionic Villi and decidual Changes of the endometrium
  • Monstrous trophoblast, hydropic chorionic villi without feral blood capillaries
  • Hematoma in Fallopian tube, chorionic villi invading the muscular layer of the tube, decidual changes of the endometrium
  • Cervical intraepithelial lesion, third grade

Pregunta 94

Pregunta
Which of the following histological changes are associated with abortion (miscarriage) ?
Respuesta
  • Chorionic Villi and decidual Changes of the endometrium
  • Monstrous trophoblast, hydropic chorionic villi without feral blood capillaries
  • Hematoma in Fallopian tube, chorionic villi invading the muscular layer of the tube, decidual changes of the endometrium
  • Cervical intraepithelial lesion, third grade

Pregunta 95

Pregunta
Specify the associated clinical symptoms in dysplasia and carcinoma in situ of the uterine cervix
Respuesta
  • No clinical symptoms
  • Scarce contact bleeding
  • Fever
  • Enlarged inguinal lymph nodes

Pregunta 96

Pregunta
Why if curettage from a suspected pregnancy shows only decidual changes, the gynaecologist should be notified immediately?
Respuesta
  • There is an increased risk for endometrial carcinoma
  • There is an increased risk of associated mola hydatidosa
  • There is an increased risk of associated intraepithelial lesion of the cervix
  • There is a high risk of associated tubal pregnancy

Pregunta 97

Pregunta
Mola hydatidosa has the following characteristics
Respuesta
  • Grossly it resembles grape-like structures
  • Chorionic villi have fetal capillaries
  • Chorionic villi are with hydropic edema
  • Chorionic villi lack fetal blood vessels

Pregunta 98

Pregunta
Examples of ovarian cysts are
Respuesta
  • Follicular cyst
  • Cystadenoma papilliferum
  • Mature teratoma (dermoid cyst)
  • Colloid cyst

Pregunta 99

Pregunta
Which hormones play a role in breast diseases?
Respuesta
  • Somatropin
  • Oxytocin
  • Estrogen
  • Progesterone

Pregunta 100

Pregunta
How does the breast cancer metastasise?
Respuesta
  • Primarily via lymphogenic spread
  • Distantly via hematogenous spread
  • Fibro-epithelial spread
  • Apocrine spread
Mostrar resumen completo Ocultar resumen completo

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