12498370
Descripción
Test por Alannah McDonnell, actualizado hace más de 1 año
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Creado por Alannah McDonnell
hace casi 7 años
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Pregunta 1
Pregunta
How much alcohol is absorbed in the stomach
Respuesta
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20%
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90%
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5%
-
0.5%
Pregunta 2
Pregunta
How much alcohol is metabolized by the liver?
Respuesta
-
20%
-
90%
-
5%
-
0.5%
Pregunta 3
Pregunta
How much alcohol is excreted by urine?
Respuesta
-
20%
-
90%
-
5%
-
0.5%
Pregunta 4
Pregunta
How is alcohol absorbed along the entire GI tract?
Respuesta
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simple diffusion
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active transport
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osmosis
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ion gated channels
Pregunta 5
Pregunta
What do alcoholic beverages primarily consist of?
Respuesta
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water
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starch
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ethanol
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sugar
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protein
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lipids
Pregunta 6
Pregunta
Which of these factors will allow you to drink more alcohol for a lower blood alcohol level content?
Respuesta
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weight
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Male
-
Female
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empty stomach
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full stomach
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carbonated mixers
Pregunta 7
Pregunta
Which of the following statements is true?
Respuesta
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Class 1 ADHs have a low Km for ethanol
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Class 1 ADHs have the lowest specificity for EtOH
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CYP2E1 has a lower Km for ethanol than class 1 ADHs
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Chronic alcohol consumption suppresses P450 enzyme systems
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Acute effects of ethanol arise from the increased NAD+/NADH ratio
Pregunta 8
Pregunta
What are the two primary pathways of alcohol metabolism?
C[blank_start]ytosol[blank_end] A[blank_start]lcohol[blank_end] D[blank_start]ehydrogenade[blank_end] (ADH)
M[blank_start]icrosomal[blank_end] ethanol-o[blank_start]xidizing[blank_end] s[blank_start]ystem[blank_end] (MEOS)
Respuesta
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Cytosol
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cellular
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Alcohol
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Adenine
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Dehydrogenase
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Deoxygenated
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Dehydrator
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Microsomal
-
Marcoscopic
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oxidizing
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oxidation reaction
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system
-
series
Pregunta 9
Pregunta
Which pathway is used for beaking down small amounts of alcohol?
Respuesta
-
Cytosol Alcohol Dehydrogenase
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Microsomal Ethanol-oxidizing system
Pregunta 10
Pregunta
Which pathway is important for breaking down large amounts of alcohol?
Respuesta
-
Microsonmal Ethanol-Oxidizing System
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Alcohol dehyrogenase
Pregunta 11
Pregunta
What can alcohol be metabolized to in the colon?
Respuesta
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ethanol
-
acetaldehyde
-
starch
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dangerous bacteria
Pregunta 12
Pregunta
What is the alcohol metabolized by in the colon?
Respuesta
-
Colon Bacterial ADH
-
Bacteria
-
amalase
-
MEOS
Pregunta 13
Pregunta
What is acetaldehyde?
Respuesta
-
a toxic compound
-
a non-toxic compount
Pregunta 14
Pregunta
What is one major effect of low doses of alcohol?
Respuesta
-
slowing the citric cycle
-
use of MEOS
-
chance of alcoholism
-
stomach issues
Pregunta 15
Pregunta
*** what is alcohol dehydrogenase?
Respuesta
-
a family of isoenzymes
-
cool
Pregunta 16
Pregunta
Which ADH has the highest specificity for ethanol?
Respuesta
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class 1 ADHs
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class 2 ADHs
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class 4 ADHs
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they're all equal
Pregunta 17
Pregunta
How many genes are there for class 1 ADH?
Respuesta
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1
-
2
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3
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4
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5
Pregunta 18
Pregunta
What do the genes for class 1 ADH exist as?
Respuesta
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allelic variants
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polymorphisms
Pregunta 19
Pregunta
which ADH class is high in the liver?
Respuesta
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1
-
2
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3
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4
Pregunta 20
Pregunta
what ADH class can be found in GIT?
Respuesta
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1
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2
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3
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4
Pregunta 21
Pregunta
which of these two are functional polymorphisms
Respuesta
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ADH 1A and ADH 1C
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ADH 2A and ADH 1C
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ADH 1X and ADH X
Pregunta 22
Pregunta
***what can partially account for observed differences in ethanol elimination rates among individuals or population?
Respuesta
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functional polymorphisms
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eating habits
Pregunta 23
Pregunta
Possession of which allele is associated with decreased susceptibility to alcoholism?
Respuesta
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ADH 1B*2
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ADH 1B*3
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ADH 1A*2
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ADH 1A*3
Pregunta 24
Pregunta
What does ADH1B*2 code for?
Respuesta
-
a relatively fast ADH
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a relative slow ADH
Pregunta 25
Pregunta
ALDH = A[blank_start]cetaldehyde[blank_end] D[blank_start]ehydrogenase[blank_end]
Respuesta
-
cetaldehyde
-
ehydrogenase
Pregunta 26
Pregunta
What type of ALDH is cytosolic?
Respuesta
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ALDH 1
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ALDH 2
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ALDH 3
Pregunta 27
Pregunta
What does accumulation of acetylaldehyde cause?
Respuesta
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nausea
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vomiting
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chest pains
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hunger
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thirst
Pregunta 28
Pregunta
What can an ALDH inhibitor be used for?
Respuesta
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Drug treatment for alcoholism
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cure for thirst
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it can't be used for anything, it's toxic
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liver repair
Pregunta 29
Pregunta
what does metabolism of acetate require?
Respuesta
-
activation to acetyl CoA
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deactivation from acetyl CoA
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reduction of Fatty Acids
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removal of a phosphate group
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