The primary excitatory neurotransmitter is ______, and ______ is the primary inhibitory neurotransmitter.
Respuesta
GABA, Glutamate
Glutamate, GABA
Dopamine, Serotonin
Adrenaline, Opiate
Pregunta 2
Pregunta
An agonist is a drug that...
Respuesta
Is always less potent than an antagonist
Elicits a similar physiological response to that of a neurotransmitter
Will usually have depressant effects
All of the above
Pregunta 3
Pregunta
The anti-depression drug Fluoxetine (also known as Prozac) increases level of serotonin. It does this by...
Respuesta
increasing serotonin production
inhibiting serotonin deterioration
indirect stimulation of serotonic cells
blocking the reuptake of synaptic serotonin
Pregunta 4
Pregunta
An increase in _____ for a drug would cause that drug to more rapidly reach the brain.
Respuesta
Metabolism of the drug via the liver
Lipid solubility
Water solubility
Kidney excretion
Pregunta 5
Pregunta
One mechanism for the tolerance produced by repeated drug administration is...
Respuesta
A decreased metabolism of the drug
An increased plasma level of the drug
An increased number of receptors for the drug
A reduced number of receptors for the drug
Pregunta 6
Pregunta
Caffeine acts to...
Respuesta
Block adenosine receptors
Stimulate adenosine receptors
Block noradrenaline receptors
Block acetylcholine receptors
Pregunta 7
Pregunta
The psychoactive constituent of the drug cannabis (THC) probably acts on the same receptors as...
Respuesta
Adenosine
Anandamide
Adenylate cyclase
Arachidonic cannabinol
Pregunta 8
Pregunta
Naloxone would be effective at reversing the effects of...
Respuesta
Dextro-amphetamine
LSD
Morphine
Both LSD and Morphine
Pregunta 9
Pregunta
Repeated administration of barbiturates/opiates may cause no increase in level of sedation/pain relief but an increasing effect on respiratory depression. Why might this be?
Respuesta
The drug begins to act as a placebo
The drug has an increased margin of safety over time
The drug has more than one site of action
The drug binds with an ionotropic receptor
Pregunta 10
Pregunta
Drugs that are postsynaptic receptor antagonists...
Respuesta
Increase neural inhibition only
Reduce neural inhibition only
Increase or reduce neural inhibition depending on the typical action of the neurotransmitter
Increase neural inhibition only when bound to a metabotropic receptor
Pregunta 11
Pregunta
A drug which prevents the storage of a neurotransmitter within synaptic vesicles would be...
Respuesta
An agonist
An antagonist
Either an agonist or an antagonist
An agonist only when calcium channels are open
Pregunta 12
Pregunta
If a drug blocks pre-synaptic transporter reuptake molecules, then it is...
Respuesta
An agonist
An antagonist
Either an agonist or an antagonist
An agonist only when sodium channels are open
Pregunta 13
Pregunta
Repeated stimulation of the mesolimbic system can lead to drug abuse. This is because...
Respuesta
This system projects to the prefrontal cortex
This system is important for reinforcement
This is an important part of the basal ganglia
This system is important in the control of the mood
Pregunta 14
Pregunta
GABA receptors are complex, but it is known that alcohol will act as...
Respuesta
An agonist to these receptors
An antagonist to these receptors
Either an agonist or an antagonist to these receptors
An agonist but only if steroid molecules are also bound to the receptor
Pregunta 15
Pregunta
Why might terahydrocannabinol (THC), the active ingredient in marijuana) be used by people taking certain drugs for cancer?
Respuesta
It reduces anxiety produced by cancer drugs
It acts as an antagonist for the neurotransmitter anandamide