Molecular Biology MCQs

Descripción

Test sobre Molecular Biology MCQs, creado por Hussain Basheer el 07/06/2019.
Hussain Basheer
Test por Hussain Basheer, actualizado hace más de 1 año
Hussain Basheer
Creado por Hussain Basheer hace más de 5 años
83
1

Resumen del Recurso

Pregunta 1

Pregunta
Which processes are parts of mRNA maturation?
Respuesta
  • splicing
  • 3´ capping
  • formation of double-stranded regions
  • polyadenylation

Pregunta 2

Pregunta
Down syndrome is caused by
Respuesta
  • a gene mutation
  • a structural chromosomal mutation
  • a numerical chromosomal mutation
  • a frameshift mutation

Pregunta 3

Pregunta
During anaphase II of meiosis
Respuesta
  • homologues separate and migrate towards opposite
  • sister chromatids separate and migrate towards opposite poles
  • nuclear membrane reforms
  • chromosomes line up in a single line

Pregunta 4

Pregunta
What is a promoter
Respuesta
  • it is a protein complex
  • it is a nucleotide sequence
  • it is needed for initiation of replication
  • it is crucial for transcription initiation

Pregunta 5

Pregunta
A primer is a short sequence of
Respuesta
  • RNA where replication starts
  • DNA where transcription starts
  • DNA where replication starts
  • RNA where translation startS

Pregunta 6

Pregunta
A primer is a short
Respuesta
  • protein sequence where replication starts
  • DNA sequence where transcription starts
  • RNA sequence where replication starts
  • RNA sequence where translation starts

Pregunta 7

Pregunta
DNA replication is
Respuesta
  • conservative
  • semiconservative
  • dispersive
  • continuous

Pregunta 8

Pregunta
Necrosis is
Respuesta
  • a result of acute chronic damage
  • controlled genetically
  • characterized by inflammation
  • characterized by rupture of the plasma membrane

Pregunta 9

Pregunta
The nucleosome
Respuesta
  • is DNA wrapped around a histone octamer
  • contains four types of histone proteins
  • is a complex of DNA and non-histone proteins;
  • contains five types of histone proteins

Pregunta 10

Pregunta
RNA Polymerase III transcribes:
Respuesta
  • mRNA;
  • 5.8S rRNA
  • tRNA
  • 5S rRNA

Pregunta 11

Pregunta
Synapsis occurs during
Respuesta
  • mitosis
  • anaphase I
  • prophase I
  • mitosis and meiosis

Pregunta 12

Pregunta
Which statements for oogenesis are true?
Respuesta
  • it is interrupted process
  • meiosis II is accomplished after fertilization
  • starts during puberty
  • has 4 distinct stages

Pregunta 13

Pregunta
Oogenesis begins
Respuesta
  • in the embryonic period
  • at birth
  • at puberty
  • in the last week of gestation

Pregunta 14

Pregunta
In oogenesis meiosis II is accomplished
Respuesta
  • at birth
  • after fertilization
  • before fertilization
  • at ovulation

Pregunta 15

Pregunta
A missense mutation
Respuesta
  • is an exchange of a coding codon with a STOP codon
  • is an exchange of a coding codon with a codon coding for another amino acid
  • a coding codon with a codon coding for the same aminoacid
  • changes the amino acid sequence of the protein

Pregunta 16

Pregunta
tRNA carries
Respuesta
  • The amino acid to the nucleuS
  • the rRNA to the mRNA
  • the mRNA to the nucleus
  • the amino acid to the ribosome

Pregunta 17

Pregunta
snRNA are localized in the
Respuesta
  • nucleus
  • cytoplasm
  • mitochondria
  • cell membrane

Pregunta 18

Pregunta
snRNA is used in
Respuesta
  • translation
  • splicing
  • polyadenylation
  • transcription

Pregunta 19

Pregunta
Helicase
Respuesta
  • separates the two DNA strands
  • elongates the newly synthesized strand
  • joins the Okazaki fragments
  • removes the supercoiling

Pregunta 20

Pregunta
Necrosis is characterized by
Respuesta
  • shrinkage of the cell
  • DNA ladder
  • rupture of the cell membrane
  • genetic program

Pregunta 21

Pregunta
In eukaryotes the first amino acid synthesized during translation is
Respuesta
  • isoleucine
  • leucine
  • methionine
  • formylmethionine

Pregunta 22

Pregunta
Western blotting is a method for detection of:
Respuesta
  • RNA
  • DNA
  • proteins
  • lipids

Pregunta 23

Pregunta
Southern blotting is a method for detection of:
Respuesta
  • RNA
  • DNA
  • sugars
  • proteins

Pregunta 24

Pregunta
Northern blotting is a method for detection of
Respuesta
  • RNA
  • DNA
  • proteins
  • lipids

Pregunta 25

Pregunta
The nitrogen bases in the DNA helix are linked by
Respuesta
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Pregunta 26

Pregunta
In metaphase of mitosis
Respuesta
  • the nucleolus breaks down
  • chromosomes are at the equator
  • the nuclear membrane reforms
  • chromosomes move to the opposite poles

Pregunta 27

Pregunta
Pyrimidines are
Respuesta
  • adenine and guanine
  • adenine and cytosine
  • thymine and guanine
  • thymine and cytosine

Pregunta 28

Pregunta
Purines are
Respuesta
  • adenine and thymine
  • thymine and guanine
  • adenine and guanine
  • thymine and cytosine

Pregunta 29

Pregunta
Mitochondrial DNA is
Respuesta
  • linear
  • single-stranded
  • inherited paternally
  • circular

Pregunta 30

Pregunta
If the mRNA has 90 codons, then the polypeptide chain is made of
Respuesta
  • 270 amino acids
  • 30 aminoacids
  • 90 amino acids
  • 60 amino acids

Pregunta 31

Pregunta
. mRNA
Respuesta
  • carries the amino acid to the ribosome
  • is synthesized in the cytoplasm
  • is the template for translation
  • contains rRNA genes

Pregunta 32

Pregunta
The acrosomal reaction
Respuesta
  • enables the entry of the sperm cell into oocyte
  • enables fusion of the male and female pronuclei
  • prevents polyspermy
  • completes meiosis II of the oocyte

Pregunta 33

Pregunta
The cortical reaction
Respuesta
  • enables the entry of the sperm cell into the oocyte
  • enables the fusion of the male and female pronuclei
  • prevents polyspermy
  • changes the membrane potential of the sperm cell membrane

Pregunta 34

Pregunta
Crossing-over occurs during
Respuesta
  • anaphase I
  • prophase I
  • mitosis
  • metaphase

Pregunta 35

Pregunta
Okazaki fragments form in the process of:
Respuesta
  • transcription
  • translation
  • splicing
  • replication

Pregunta 36

Pregunta
. A missense mutation changes the
Respuesta
  • amino acid sequence of the protein
  • open reading frame of the gene
  • order of codons within the gene
  • position of the TATA box in the promoteR

Pregunta 37

Pregunta
PCR is a method for amplification of
Respuesta
  • RNA
  • DNA
  • sugars
  • proteins

Pregunta 38

Pregunta
47 XX+21 is the genetic formula of a female with
Respuesta
  • Turner syndrome
  • Down syndrome
  • Kleinfelter syndrome
  • Edwards syndrome

Pregunta 39

Pregunta
A male with a karyotype 47, XXY has
Respuesta
  • Turner syndrome
  • Kleinfelter syndrome;
  • Down syndrome
  • Edwards syndrome

Pregunta 40

Pregunta
A female with a karyotype 45, X0 has
Respuesta
  • Turner syndrome
  • Kleinfelter syndrome
  • Down syndrome
  • Edwards syndrome

Pregunta 41

Pregunta
The genetic formula 45, XO is typical of
Respuesta
  • Down syndrome
  • Kleinfelter syndrome
  • Turner syndrome
  • Edwards syndrome

Pregunta 42

Pregunta
Turner syndrome is
Respuesta
  • trisomy of the X chromosome
  • monosomy of the X chromosome
  • monosomy of the Y chromosome
  • trisomy of the Y chromosome

Pregunta 43

Pregunta
Edwards syndrome is a trisomy of chromosome
Respuesta
  • 12
  • 21
  • 23
  • 18

Pregunta 44

Pregunta
In proteins amino acids are linked by
Respuesta
  • peptide bonds
  • disulfide bridges
  • hydrogen bonds
  • triphosphate bridges

Pregunta 45

Pregunta
In anaphase of mitosis
Respuesta
  • The nucleolus breaks down
  • chromosomes are at the equator
  • the nuclear membrane reforms
  • chromosomes move to the opposite poles

Pregunta 46

Pregunta
In meiosis sister chromatids separate during
Respuesta
  • metaphase I
  • telophase II
  • anaphase II
  • prometaphase I

Pregunta 47

Pregunta
An enhancer is a
Respuesta
  • nucleotide sequence
  • protein complex
  • transcription factor
  • ribozyme

Pregunta 48

Pregunta
In DNA nucleotides are linked by
Respuesta
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Pregunta 49

Pregunta
The functions of miRNAs are
Respuesta
  • coding
  • enzymatic
  • transporting
  • regulatory

Pregunta 50

Pregunta
The nitrogen bases in the DNA helix are linked by
Respuesta
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Pregunta 51

Pregunta
The 5’ cap is important for
Respuesta
  • snRNA stability
  • formation of the spliceosome
  • termination of transcription
  • mRNA transport into the cytoplasm

Pregunta 52

Pregunta
The TATA sequence is commonly found in:
Respuesta
  • telomeres
  • centromeres
  • promoters
  • enhancers

Pregunta 53

Pregunta
In meiosis sister chromatids separate during
Respuesta
  • metaphase I
  • telophase II
  • anaphase II;
  • prometaphase I

Pregunta 54

Pregunta
The Robertsonian translocation is a
Respuesta
  • structural chromosomal mutation
  • gene mutation
  • point mutation
  • separation of metacentric chromosomes.

Pregunta 55

Pregunta
Which proteins control the cell cycle?
Respuesta
  • snRNPs
  • activators
  • CDKs
  • promoters

Pregunta 56

Pregunta
Polyadenylation occurs at
Respuesta
  • the 5’ end of DNA during replication
  • the 3’ end of rRNA during transcription
  • the 5’ end of mRNA during transcription
  • the 3’ end of mRNA during transcription

Pregunta 57

Pregunta
The spliceosome contains
Respuesta
  • transcription factors
  • endonucleases
  • snRNPs
  • enhancers

Pregunta 58

Pregunta
Capacitation is a reaction that occurs in
Respuesta
  • oogenesis
  • spermatogenesis
  • fertilization
  • meiosis

Pregunta 59

Pregunta
The START codon for translation is
Respuesta
  • AAU
  • AUU
  • AUG
  • AUC

Pregunta 60

Pregunta
How many types of rRNA exist in eukaryotes?
Respuesta
  • 1
  • 2
  • 3
  • 4

Pregunta 61

Pregunta
DNA replication takes place during
Respuesta
  • S phase
  • G1 phase
  • metaphase
  • telophase

Pregunta 62

Pregunta
Prokaryotic mRNA
Respuesta
  • is monocistronic
  • contains introns;
  • has a 5’ cap
  • has more than one cistron

Pregunta 63

Pregunta
Heterochromatin
Respuesta
  • contains functional genes
  • is decondensed
  • replicates late in the S phase
  • is lightly stained

Pregunta 64

Pregunta
Euchromatin
Respuesta
  • is darkly stained
  • is replicated late in the S phase
  • contains functional genes
  • is highly condensed

Pregunta 65

Pregunta
Apoptosis
Respuesta
  • causes inflammation
  • is under genetic control
  • is caused by rupture of the cell membrane
  • causes enlargement of the cell

Pregunta 66

Pregunta
Which enzymes promote apoptosis?
Respuesta
  • snRNPs
  • topoisomerases
  • polymerases
  • caspases

Pregunta 67

Pregunta
Intron is the
Respuesta
  • coding region of a gene
  • non-coding region of a gene
  • 2 nucleotides that code for one amino acid
  • 3 nucleotides that code for one amino acid

Pregunta 68

Pregunta
Exon is the:
Respuesta
  • coding region of a gene
  • non-coding region of a gene
  • 2 nucleotides that code for one amino acid
  • 3 nucleotides that code for one amino acid

Pregunta 69

Pregunta
Spermatogenesis
Respuesta
  • is an interrupted process
  • begins at birth
  • has 4 distinct stages
  • is very inefficient

Pregunta 70

Pregunta
The consequence of a nonsense mutation is
Respuesta
  • change in the amino acid sequence
  • truncated protein
  • shift of the open reading frame
  • different codon order

Pregunta 71

Pregunta
The first AUG sequence in eukaryotes is located in the
Respuesta
  • Shine-Dalgarno sequence
  • Kozak sequence
  • Pribnow box
  • TATA box

Pregunta 72

Pregunta
Kozak sequence
Respuesta
  • tRNA
  • mRNA
  • rRNA
  • snRNA

Pregunta 73

Pregunta
Which method is used for DNA amplification?
Respuesta
  • Southern blot
  • Northern blot
  • PCR
  • RT-PCR

Pregunta 74

Pregunta
Which enzyme is not involved in DNA replication?
Respuesta
  • RNA polymerase
  • ligase
  • RNA primase
  • telomerase

Pregunta 75

Pregunta
The acrosome is:
Respuesta
  • an organelle at the tip of the sperm cell
  • the site where the flagellum of the sperm cell begins
  • an organelle in the perivitelline space of the oocyte
  • the vitelline envelope of the sperm cell

Pregunta 76

Pregunta
The polypeptide chain is built up of
Respuesta
  • fatty acids
  • amino acids
  • disaccharides
  • polysaccharides

Pregunta 77

Pregunta
In oogenesis meiosis II is accomplished
Respuesta
  • at birth
  • after fertilization
  • before fertilization
  • at ovulation

Pregunta 78

Pregunta
The nucleosome
Respuesta
  • Contains H2A, H2B, H3, H4 histone molecules;
  • contains 2 types of histone molecules
  • is DNA wrapped around a non-histone octamer
  • contains 6 types of histone molecules

Pregunta 79

Pregunta
The ribosome is a complex of
Respuesta
  • DNA and proteins
  • mRNA and tRNA
  • rRNA and polysaccharides
  • rRNA and proteins

Pregunta 80

Pregunta
Restriction enzymes are used in
Respuesta
  • DNA replication
  • DNA cloning
  • RNA replication
  • RNA restriction

Pregunta 81

Pregunta
Which nucleic acid functions as a ribozyme?
Respuesta
  • mRNA
  • DNA
  • rRNA
  • ssDNA

Pregunta 82

Pregunta
Plasmids are circular DNAs in
Respuesta
  • mammalian cells
  • viruses
  • bacterial cells
  • sperm cells

Pregunta 83

Pregunta
. The nucleosome contains
Respuesta
  • an octamer of histones and 246 bp of DNA
  • an octamer of histones and 146 bp of DNA
  • a hexamer of histones and 146 bp of DNA
  • a hexamer of histones and 146 bp of RNA

Pregunta 84

Pregunta
SSB proteins are required for
Respuesta
  • transcription
  • translation
  • splicing
  • replication

Pregunta 85

Pregunta
Which enzyme does not take part in DNA replication?
Respuesta
  • helicase
  • ligase
  • RNA primase
  • RNA polymerase

Pregunta 86

Pregunta
Which enzyme unwinds DNA?
Respuesta
  • DNA-polymerase
  • helicase
  • transferase
  • topoisomerase

Pregunta 87

Pregunta
What is the sequence of the mRNA, if the DNA antisense strand is AATCCGGAT?
Respuesta
  • 5’ ATCCGGATT 3’
  • 5’ TTAGGCCTA 3’
  • 5’ AUCCGGAUU 3’
  • 5’ UUAGGCCUA 3’

Pregunta 88

Pregunta
Topoisomerase
Respuesta
  • removes supercoiling of DNA
  • separates the two DNA strands
  • destroys the nuclear envelope
  • forms the peptide bond
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