Pregunta 1
Pregunta
Which of the following methods is suitable for detectin of serum globulins?
Pregunta 2
Pregunta
Type II allergic reations are realized by
Pregunta 3
Pregunta
Monoclonal antibodies are
Respuesta
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pure population of immunoglobulins with same structure ant antigen specifity
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albumins that are coded from other group of genes
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mixed population of immunoglobulins with same structure, but different antigen specifity
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substrate causing expression of immunoglobulins from other class in B-cells
Pregunta 4
Pregunta
Which immunological method is not proper for detecting of specific IgE
Respuesta
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Immuno-enzyme(ELİSA, immuno-blot technique)
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Classical ones(agglutination, precuipitation)
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Floucytometry
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Chemilluminescence
Pregunta 5
Pregunta
Low levels of IgA are found in case of
Pregunta 6
Pregunta
Auto immune disease due to antibodies could be a result of (point the wrong answer)
Respuesta
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forming of antigen-antibody complexes
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antibodies that blockade cell receptor
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antibody-depended cell-mediated cytotocicitty(ADCC)
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cell-mediated reaction
Pregunta 7
Pregunta
The name of resident macrophages in liver is
Respuesta
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ostephages
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lagerhance cells
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kupfer cells
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microglial
Pregunta 8
Respuesta
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Hepatoma
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Nasopharyngeal carcinoma
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Burkit lymphoma
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Adenocaqrcinoma pulmonis
Pregunta 9
Pregunta
Which of the following indicators is the most important in case of detecting of immune status in AIDS
Respuesta
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NBT test
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Anti-DNA antibodies
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CD4/CD8 index
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The bence-jones protein
Pregunta 10
Pregunta
System lupus erythematosus
Respuesta
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is caused by mutations in ds-DNA
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is revealed with many symptoms and affects many organs
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is an example of T-cell mediated disease
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is a result of generating of immune complexes
Pregunta 11
Pregunta
The opsonisation is a process of
Respuesta
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Ingestion and destruction of an antigen from phagocyte
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Of covering of antigen with antibodies in purpose to ease phagocytosis
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Of covering of antigen with complement in purpose to ease phagoytosis
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Obtaining of monoclonal antibodies
Pregunta 12
Pregunta
Connect with arrows allergic diseases with relevant types allergic reactions:
Type [blank_start]3[blank_end] - serum-disease
Type [blank_start]4[blank_end] - contact dermatitis
Type [blank_start]1[blank_end] - anaphylaxis
Type [blank_start]2[blank_end]- hemolytic disease of newborn
Respuesta
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3
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1
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2
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4
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4
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1
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2
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3
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1
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2
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3
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4
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2
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1
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3
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4
Pregunta 13
Pregunta
The mature B-lymphocytes expresses onto their surface
Respuesta
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IgM and IgD
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IgM and IgA
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IgD and IgE
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IgG and IgD
Pregunta 14
Pregunta
The lymphocyte infiltration of thyroidea is typical for
Pregunta 15
Pregunta
The electrophoresis is
Respuesta
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radial immunodiffusion in gel
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separation of molecules in electric field
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complement fixation reaction
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electroimmunodiffusion
Pregunta 16
Pregunta
I type allergic reactions are
Respuesta
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Immunocomplex
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Cytotoxic
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IgE mediated
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Cell mediated
Pregunta 17
Pregunta
Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics
a. Multiple sclerosis [blank_start]6[blank_end]
b. SLE [blank_start]4[blank_end]
c. Myasthenia gravis [blank_start]5[blank_end]
d. Pernicious anemia [blank_start]1[blank_end]
e. Hashimoto thyoiditis [blank_start]2[blank_end]
f. Hemolytic anemia [blank_start]3[blank_end]
1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12
2. autoantibodies against thyroglobuline and thyroid peroxidase
3. antibodies against epitopes of red blood cells
4. antibodies against nucleus antigens
5. antibodies against acetylcholine
6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
Respuesta
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6
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1
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2
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3
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4
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5
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4
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5
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1
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6
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1
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1
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5
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6
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3
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1
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2
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4
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5
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6
Pregunta 18
Pregunta
The monoclonal antibodies, connected with diphtheria toxin could be used for
Respuesta
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tumour diagnosis
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immunostimulation
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immunosupperession
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immunotherapy of tumors
Pregunta 19
Pregunta
The defensins are
Pregunta 20
Pregunta
What is the mechanism of III type allergic reactions
Pregunta 21
Pregunta
Which of the following tumour markers are connected with melanoma maligna?
Respuesta
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CA-15-3
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gp 120
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S100B
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MART-1Melan A
Pregunta 22
Pregunta
Immuno-scintigraphy uses monoclonal antibodies against tumour antigen connected with
Respuesta
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FITC
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Rhodamine
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Iodine 131, technetium
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Enzyme
Pregunta 23
Pregunta
INF-γ is produced by
Respuesta
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Activated T lymphocytes
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Fibroblasts
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B-lymphocytes
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Leucocytes
Pregunta 24
Pregunta
What kind of auto-antibodies we find in patients with insulin-depended sugar diabetes?
Respuesta
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Nucleus
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Thyroid microsomes
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IgG molecules
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Island cells of pancreas
Pregunta 25
Pregunta
Rejection of a transplantant due to pre-forming antibodies in recipient is defined as
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Hyper acute rejection
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Accelerated
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Acute
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Chronic
Pregunta 26
Pregunta
What of the following possesses the most expressed oncogenic potential
Respuesta
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Influenza virus type A
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Ebola virus
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EBV
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Polioviruses 1,2 ,3
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HPV
Pregunta 27
Pregunta
Is the following correct?
Active immunity is a nospecific and is an ancient form of defense and lower degree of effectiveness?
Pregunta 28
Pregunta
Type IV allergic reactions are realized by means of
Pregunta 29
Pregunta
True hypersensitivity reactions start usually after
Pregunta 30
Pregunta
Which of the following characteristics does not belong to the Burkit lymphoma?
Pregunta 31
Pregunta
Antigen presenting cells are
Pregunta 32
Pregunta
We could use the mantoux test in diagnosis of (point two diseases)
a- [blank_start]Tuberculosis[blank_end]
b- [blank_start]Leprosy[blank_end]
Pregunta 33
Pregunta
Which of the following factors belong to the innate immunity?
Respuesta
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Phagocytosis
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T-lymphocytes
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Complement, mucin, a-and b inferferons
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Antibodies
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Skin, mucus, normal flora
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B-lymphocytes
Pregunta 34
Pregunta
What we could use as a subsrrate for detection of antinuclear antibodies throguh IFA?
Respuesta
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rat liver
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rat kidney
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rat stomach
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hep2 cell line
Pregunta 35
Pregunta
Which of the pointed immunological parameters is most important for detection of multiple myleoma?
Respuesta
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NBT test
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Anti-DNA antibodies
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CD4/CD8 index
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The Bence-jones protein
Pregunta 36
Pregunta
The most popular techniques for detection of antinuclear antibodies are
Respuesta
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Agglutination
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Indirect immunofluorescence
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Neutralization test
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The complement fixation test
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ELISA
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Direct immunofluorescence
Pregunta 37
Pregunta
CD3 molecule is a marker for
Pregunta 38
Pregunta
The accelerated reaction for rejection of transplantant is revealed
Respuesta
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Intra-operative or immediately after operation
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24-to 72 hours after transplantation
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Till the third month
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3 month after the transplantation
Pregunta 39
Pregunta
which of the following immunological indexes ids the most important for patients with chronic granulomatous disease?
Respuesta
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NBT test
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Anti DNA antibodies
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CD4/CD8 index
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The Bence-jones protein
Pregunta 40
Pregunta
CEA is increased in case of
Respuesta
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nasopharyngeal carcinoma
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the Burkit lymphoma
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gatro-intestinal tumors
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smokers
Pregunta 41
Pregunta
Which of the following is connected with damage of humoral immunity?
Pregunta 42
Pregunta
How many are complement activating ways?
Pregunta 43
Pregunta
The complement activation occurs via three pathways which are:
1. [blank_start]Classical[blank_end] pathway
2. [blank_start]Alternative[blank_end] pathway
3. [blank_start]Lectin[blank_end] pathway
Respuesta
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Classical
-
Alternative
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Lectin
Pregunta 44
Pregunta
The “respiratory burst" is related to
Respuesta
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Humoral immunity
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Cellular immunity
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Phagocytosis
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NK-cells function
Pregunta 45
Pregunta
The immune competence of T-lymphocytes is acquired in
Respuesta
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Thyroidea
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Bone marrow
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Thymus
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MALT
Pregunta 46
Pregunta
What expresses the CD8 molecule?
Respuesta
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Macrophages
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Antigen presenting cells
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Cytotoxic T-lymphocytes
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T- suppressors
Pregunta 47
Pregunta
What is human cell receptor for human immunodeficiency virus (HIV)?
Respuesta
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CD3 molecule
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CD8 molecule
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CD4 molecule
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CD19 molecule
Pregunta 48
Pregunta
Point the WRONG answer:
Gamma interteron is produced by:
Respuesta
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Non-activated macrophages and mastocytes
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Leucocytes and Fibroblasts
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Activated macrophages and NK cell
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Lymphocytes
Pregunta 49
Pregunta
The determination of functional activity of the complement might be done by
Pregunta 50
Pregunta
CD4 molecule is situated on the surface of the
Respuesta
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Monocytes
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T-helpers
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Cytotoxic T-lymphocytes
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Plasmocytes
Pregunta 51
Pregunta
The presence of the antigen together with the MHC-II class molecules is realized by
Pregunta 52
Pregunta
A B-cell can synthesise some different antibodies with different species of the antigen
Pregunta 53
Pregunta
After the antigen stimulus the mature B-lymphocytes are transformed into
Respuesta
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cytotoxic cell
-
immunocompetent cell
-
plasmocyte
Pregunta 54
Pregunta
What tests are for evaluation of the phagocytic activity?
Pregunta 55
Pregunta
Paraproteinemias are detected in
Pregunta 56
Pregunta
Last cells, incapable to divide are
Respuesta
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Plasmocytes
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Neutrophils
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T-lymphocytes
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B-Iymphocytes
Pregunta 57
Pregunta
What do the mature B-lymphocytes express on their surface?
Respuesta
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lgM and IgD
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IgD ant IgE
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IgM and IgA
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IgG and IgD
Pregunta 58
Pregunta
How do CD8 eliminate their targets?
Respuesta
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after recognition of antigen, connected with MCH-I class molecule
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after recognition of antigen connected with MCH-II class molecule
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via activation of an alternative way of complement
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due releasing of interferon