222007
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace alrededor de 11 años
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Pregunta 1
Pregunta
Which type of protein is conjugated?
Respuesta
-
One that contains only amino acid residues
-
One that contains prosthetic groups
-
One that is bound to a membrane
Pregunta 2
Pregunta
Which of the following means a protein with two identical subunits?
Respuesta
-
Heteromultimer
-
Homomonomer
-
Homomultimer
Pregunta 3
Pregunta
Which of the following proteins types tend to have various roles, as opposed to a single, defined one?
Respuesta
-
Fibrous
-
Globular
-
Membrane
Pregunta 4
Pregunta
Which of the following tend not to be water soluble?
Respuesta
-
Fibrous
-
Globular
-
Membrane spanning
Pregunta 5
Pregunta
What secondary structures tend to make up fibrous proteins?
Respuesta
-
Long strands
-
Long sheets
-
Short strands
Pregunta 6
Pregunta
What is specific about the membrane spanning part of membrane proteins?
Respuesta
-
They are hydrophobic
-
They are hydrophillic
Pregunta 7
Pregunta
Define 'Domain' in reference to protein structure
Respuesta
-
Independent folding units of the tertiary structure that have independent functions
-
Independent folding units of tertiary structure that have related functions
-
Dependent folding units of secondary structure that have relation functions
-
Dependent folding units of tertiary structure that have related functions
Pregunta 8
Pregunta
Define subunit
Respuesta
-
Independent structures in a quaternary structure
-
Independent structures in a tertiary structure
-
Dependent subunits in a quaternary structure
Pregunta 9
Pregunta
What can be the result of a single amino acid mutation in collagen?
Respuesta
-
Osteoarthritis
-
Osteogenesis imperfecta
-
Osteocalcification
Pregunta 10
Pregunta
What is Resonance (as pertaining to protein structure)?
Respuesta
-
Where bond pairs cannot be described as a single Lewis Diagram
-
Where two atoms in separate molecules cause each other to vibrate
-
Where two atoms in separate molecules are more likely to bond to each other than to another atom
Pregunta 11
Pregunta
Which is the psi bond?
Respuesta
-
Between the carbonyl carbon and the alpha carbon
-
Between the alpha carbon and the amide group
-
Between the alpha carbon and the R group
Pregunta 12
Pregunta
Which is the phi bond?
Respuesta
-
Between the alpha carbon and the amide group
-
Between the alpha carbon and the carbonyl carbon
-
Between the alpha carbon and the R group
Pregunta 13
Pregunta
What is Steric clashing?
Respuesta
-
Where the charge of an atom prevents it from being close to another
-
Where the electron arrangement of an atom prevents it from being close to another
-
Where the size of an atom prevents it from being close to another
Pregunta 14
Pregunta
Why is a peptide bond planar?
Respuesta
-
It has a double bond like structure
-
It's electrons clash with that of the psi bond
-
It's electrons clash with the phi bond
Pregunta 15
Pregunta
How many residues per turn in an alpha helix?
Respuesta
-
3.4
-
3.5
-
3.6
Pregunta 16
Pregunta
How much does an alpha helix rise per aa?
Respuesta
-
1.5 angstroms
-
1.6 angstroms
-
1.7 angstroms
Pregunta 17
Pregunta
Alpha helices are stabilised by hydrogen bonding with what groups?
Respuesta
-
Carbonyl oxygen 4 amino acids away
-
Carbonyl oxygen 6 amino acids away
-
Carbonyl oxygen 8 amino acids away
Pregunta 18
Pregunta
The stabilising effect of the hydrogen bonds makes a loop of how many atoms?
Respuesta
-
12
-
13
-
14
Pregunta 19
Pregunta
Which of the following destabilize an alpha helix?
Respuesta
-
Glycine
-
Proline
-
Leucine
-
Glutamic acid
Pregunta 20
Pregunta
Beta sheets rise by 3.47A per residue in anti-parallel sheets
Respuesta
- True
- False
Pregunta 21
Pregunta
In parallel sheets, there is a rise of .... per residue
Respuesta
-
3.25A
-
4.25A
-
2.25A
Pregunta 22
Pregunta
3 residues per turn of the strand are pictured as a helix
Respuesta
- True
- False
Pregunta 23
Pregunta
Anti-parallel strands are _ stable than parallel ones
Respuesta
-
More
-
Less
Pregunta 24
Pregunta
Side chains all point the same way (in the plane of the sheet)
Respuesta
- True
- False
Pregunta 25
Pregunta
What is the role of loops?
Respuesta
-
Connecting alpha and beta sheets
-
Connecting alpha helices and alpha helices
-
Connecting beta sheets and beta sheets
Pregunta 26
Pregunta
Loops contain mostly hydrophillic residues & are found on the protein surface
Respuesta
- True
- False
Pregunta 27
Pregunta
What is the role of beta turns?
Respuesta
-
To allow beta sheets to reverse direction
-
To connect beta sheets together
-
To link protein subunits together
Pregunta 28
Pregunta
What two amino acids cannot be contained within a beta sheet?
Respuesta
-
Proline
-
Argenine
-
Glycine
-
Valine
Pregunta 29
Pregunta
Beta turns link the oxygen of the carbonyl group and the hydrogen of the nitrile group 4 residues away
Image:
Beta_Turns (image/jpg)
Respuesta
- True
- False
Pregunta 30
Pregunta
Levinthals Paradox- if a protein folded by trying each fold in a sequence, it would take an impossibly long time to fold correctly. Therefore, protein folding cannot be random or sequential
Respuesta
- True
- False
Pregunta 31
Respuesta
-
The energy change as proteins fold
-
Gibbs free energy
-
Entropy change
Pregunta 32
Pregunta
Why are the internal interactions of protein folding unfavorable?
Respuesta
-
It decreases entropy
-
They're hydrophobic in a hydrophillic environment
-
They prevent the protein from folding correctly
Pregunta 33
Pregunta
Non-covalent and hydrophobic effects (which effects free water) decrease enthalpy
Respuesta
- True
- False
Pregunta 34
Pregunta
Change in energy during folding = Internal interactions - (Hydrophobic effect + conformational entropy)
Respuesta
- True
- False
Pregunta 35
Pregunta
Proteins fold towards configurations with the...
Respuesta
-
lowest energy
-
Highest energy
-
Easiest energy to reach (energy closest to that of unfolded protein)
Pregunta 36
Pregunta
What can slow the progress of protein folding?
Respuesta
-
A local low energy minimum
-
A local high energy minimum
Pregunta 37
Pregunta
What is nucleation?
Respuesta
-
Reversible secondary structure formation
-
Reversible tertiary structure formation
-
Reversible quaternary structure formation
Pregunta 38
Pregunta
Which of the following happens after nucleation?
Respuesta
-
The secondary structure aggregation forms a molten globular intermediate
-
Domains adjust to the lowest energy form
Pregunta 39
Pregunta
The protein is capable of conformational change after forming
Respuesta
- True
- False
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