22674602
Descripción
Test por Med Student , actualizado hace más de 1 año
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Creado por Med Student
hace más de 4 años
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Pregunta 1
Pregunta
Which are the main goals of nuclear oncology
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Imaging of the functional activity and the degree of proliferation of the tumor
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The degree of malignant tumor spread: lymphogenic and haematogenic
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Imaging and quantitative assessment of the effect from chemo- and hormone-therapy
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All answers are correct
Pregunta 2
Pregunta
The scanning systems used in nuclear medicine are based on the principle of
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Emission of Gamma-rays from the scanning system
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Transition of Roentgen-rays through the patient's body
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Detection of Gamma-rays or positron emission (pairs of annihilation Gamma-rays) emitted from the studied object
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All answers are correct
Pregunta 3
Pregunta
Which methods of nuclear medicine are used for diagnosis of malignant tumours
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PET/CT
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Gamma camera scintigraphy
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Radioimmunoassay of tumour markers
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All answers are correct
Pregunta 4
Pregunta
Nuclear medicine diagnosis provides
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Metabolic imaging
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Quantitative assessment of physiological processes in the human body
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Targeted planning of radiotherapy
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All answers are correct
Pregunta 5
Pregunta
Nuclear medicine applies
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Unsealed radioactive sources for medical diagnosis
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Unsealed radioactive sources for radiotherapy
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Sealed radioactive sources for medical diagnosis and therapy
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Correct answers- a) and b)
Pregunta 6
Pregunta
PET/CT is a multimodality system combining
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PET scanner with low-dose CT for improvement of the quality and precise localization of the functional image
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PET scanner with possibility for additional targeted diagnostic contrast CT
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Acquisition and fusion of functional and structural-anatomic images
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All answers are correct
Pregunta 7
Pregunta
CT and PET scans demonstrate different aspects of disease indicating regions with
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Altered metabolism (PET) and areas of structural change (CT)
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Altered metabolism (CT) and areas of structural change (PET)
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Altered metabolism (PET) and areas of structural change (PET)
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Altered metabolism (CT) and areas of structural change (CT)
Pregunta 8
Pregunta
Which of the following diagnostic methods belong to modern Nuclear medicine
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PET/CT
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SPECT/CT
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PET/MRI
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All answers are correct
Pregunta 9
Pregunta
Which radionuclides are used for metabolic brachytherapy
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High-energy γ (Gamma) emitters
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β- (Beta)-emitters
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β- (Beta) and γ (Gamma)-emitters
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Correct answers — b) and c)
Pregunta 10
Pregunta
Nuclear medicine methods are used for
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Diagnosis of benign and malignant diseases
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Treatment of benign diseases
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Treatment of malignant diseases
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All answers are correct
Pregunta 11
Pregunta
PET /CT imaging has demonstrated significant application in the following clinical areas EXCEPT
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Oncology
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Cardiology
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Pulmonology
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Neurology
Pregunta 12
Pregunta
Which radiopharmaceuticals are used for tumor-specific imaging
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131 I- NaI
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III In-Octreoscan
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99m Tc-Tetrofosmin
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All answers are correct
Pregunta 13
Pregunta
Malignant tumors present on scintigraphy with tumor-specific radiopharmaceuticals as
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Zones of increased uptake of the radiopharmaceuticals
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Zones of decreased uptake of the radiopharmaceuticals
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Zones of absent uptake of the radiopharmaceuticals
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Zones of normal uptake of the radiopharmaceuticals
Pregunta 14
Pregunta
The most frequently used radiopharmaceutical for PET/CT imaging is
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18F-FDG
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99mTc-Pertechnetate
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131-Iodine — Nal
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No correct answer
Pregunta 15
Pregunta
The PET scanner is detector of
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Alfa-particles
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Beta-particles
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Pairs of annihilation Gamma rays
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All answers are correct
Pregunta 16
Pregunta
Bone scintigraphy is
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Highly specific diagnostic method
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Highly sensitive diagnostic method
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Highly sensitive and highly specific diagnostic method
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Non-sensitive and non-specific diagnostic method
Pregunta 17
Pregunta
The main indication for bone scintigraphy is
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Inflammatory bore disorders
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Early detection of bone metastases
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Benign bone tumors
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Degenerative joint disorders
Pregunta 18
Pregunta
Metabolic brachytherapy with Metastron (89 Stroncium) is applied in patients with
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Bone metastases
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Pulmonary metastases
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Brain metastases
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Liver metastases
Pregunta 19
Pregunta
Contraindication for metabolic brachytherapy in patients with metastatic bone disease is
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Advanced stage of the disease
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Considerable myelo-depression
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Inflammatory conditions
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All answers are correct
Pregunta 20
Pregunta
Differentiated Thyroid cancer after total thyroidectomy and manifested distant haematogenic metastases is treated successfully with
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Operation
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Radioiodine metabolic brachytherapy
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Chemotherapy
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Electron therapy
Pregunta 21
Pregunta
Which of the following statements describing 18-F FDG PET imaging in thyroid carcinoma is FALSE
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18-F FDG PET can be negative in well differentiated types
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18-F FDG PET negative lesions are more likely to be resistant to 1-131 treatment
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18-F FDG uptake is proportional to Iodine uptake
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18-F FDG PET may not be accurate in patient with Tg levels below 2 ng/ dL
Pregunta 22
Pregunta
The most specific method for follow-up after treatment of Differentiated thyroid cancer is
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Roentgenography
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Thyroglobulin
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Whole-body scintigraphy with 131-Iodine
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Correct answers — b) and c)
Pregunta 23
Pregunta
A Thyroid cancer presents on the conventional scintigram with 99mTc as
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Hot nodule
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Warm nodule
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Cold nodule
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All answers are correct
Pregunta 24
Pregunta
Which histologic types of Thyroid cancer COULD NOT be treated with 131-Iodine metabolic brachytherapy
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Papillary
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Follicular
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Medullary and anaplastic
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Correct answers — a) and b)
Pregunta 25
Pregunta
An oncology patient referred for PET/CT should fast prior to the appointment for at least
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12h
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8h
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4h
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2h
Pregunta 26
Pregunta
The recommended time interval for PET/CT. imaging after biopsy is
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1 week
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2-4 weeks
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2-6 months
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more than 6 months
Pregunta 27
Pregunta
In order to avoid false-positive results, FDG PET/ CT scans should be performed
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1-2 weeks after the last cycle of chemotherapy
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2-4 weeks after the last cycle of chemotherapy
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4-6 weeks after the last cycle of chemotherapy
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6-8 weeks after the last cycle of chemotherapy
Pregunta 28
Pregunta
False-negative PET/CT scans in lung cancer imaging occur predominantly because of
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Lesions are too big to be evaluated by PET
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Lesions are too superficial to be evaluated by PET
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Lesions are too small to be evaluated by PET
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Lesions are too deep to be evaluated by PET
Pregunta 29
Pregunta
F-18 FDG PET/CT is considered as a superior modality, compared with CT for evaluating post-treatment response in lymphoma patients because of
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The ability to provide anatomical information
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The ability to differentiate viable tumour from fibrosis
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Higher resolution
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Shorter imaging
Pregunta 30
Pregunta
A breast-feeding patient referred for PET/CT imaging should
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Discontinue breast-feeding 12 h before injection of radiotracer
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Discontinue breast-feeding 6 h before injection of radiotracer
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Discontinue breast-feeding for at least 6 h after injection of radiotracer
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Discontinue breast-feeding for at least 12 h after injection of radiotracer
Pregunta 31
Pregunta
A PET quantifier, calculated as the tracer activity concentration within a volume of interest divided by the injected dose per unit body weight is
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Fractional uptake value
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Standardized upload value
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Standardized uptake value
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Fractionai upload value
Pregunta 32
Pregunta
The Standardized Uptake Value (SUV) is
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The measured activity divided by the body mass
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The amount of tracer needed for a particular body weight
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The measured activity normalized for body weight and inject dose
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The measured activity within a particular organ divided by the sampled volume
Pregunta 33
Pregunta
For optimal patient care and interpretation of FDG PET/CT images, the following information from the patient should be obtained
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Breast-feeding info
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Recent surgery info
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Use of medication info
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All answers are correct
Pregunta 34
Pregunta
FDG PET/CT provides beneficial information in all of the following areas of lymphoma evaluation EXCEPT
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Diagnosis
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Response to therapy
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Recurrence detection
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Staging
Pregunta 35
Pregunta
Which of the following statements correctly explains the influence of FDG PET/CT imaging on staging in patients with Hodgkin's lymphoma
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Upstaging of approximately 15-25 % of patients
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Down-staging in a small minority of patients
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Upstaging in a small minority of patients
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Down-staging of approximately 15-25 % of patients
Pregunta 36
Pregunta
All of the following are well-established indications for FDG PET/CT imaging in patients with recurrent colorectal carcinoma EXCEPT
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Falling CEA levels in the absence of a known source
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Staging recurrent colorectal carcinoma
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Preoperative staging
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Equivocal lesion on conventional imaging
Pregunta 37
Pregunta
When monitoring response to treatment with FDG PET/CT Imaging is essential to obtain
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Baseline FDG PET/CT scan
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Interim FDG PET/CT scan
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FDG PET/CT scan on the last day of therapy
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FDG PET/CT scan two days after therapy
Pregunta 38
Pregunta
FDG uptake by cancer cells tends to decline as
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Blood glucose and insulin levels decrease
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Blood glucose level decrease and insulin levels increase
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Blood glucose and insulin levels increase
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Blood glucose level increase and insulin levels decrease
Pregunta 39
Pregunta
All of the following statements describe the usefulness of FDG PET/CT imaging in malignant pleural mesothelioma (MPM) EXCEPT
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FDG PET/CT reduces the number of futile surgical procedures
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FDG PET/CT imaging is useful for guiding needle biopsy
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FDG PET/CT increases the accuracy of overall MPM staging
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High levels of FDG uptake are associated with a favourable prognosis
Pregunta 40
Pregunta
The intensity of FDG uptake in the majority of mesotheliomas
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Ranges from absent to low
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Ranges from low to moderate
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Ranges from moderate to high
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Is always high
Pregunta 41
Pregunta
Selected tumours with low FDG uptake include all of the following EXCEPT
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Prostate carcinoma
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Iodine-avid differentiated thyroid carcinoma
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Metastatic liver carcinoma
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Hepatocellular carcinoma
Pregunta 42
Pregunta
All of the following statements correctly describe the postsurgical 18-F FDG uptake at the intervention site EXCEPT
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Postsurgical 18-F FDG uptake is mainly diffuse
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Postsurgical 18-F FDG uptake corresponds to the site of surgery
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Postsurgical 18-F FDG uptake increases in intensity with time
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Postsurgical 18-F FDG uptake in size with time
Pregunta 43
Pregunta
18-F FDG PET/CT should be performed on patients previously treated for differentiated thyroid cancer when the finding of 131-I whole body scintigraphy are negative and
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The thyroglobuline (Tg) levels are more than 10 ng/ mL
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The thyroglobuline (Tg) levels are less than 10 ng/ mL
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The TSH levels are more than 30 mIU/L
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The TSH levels are less than 30 mIU/ L
Pregunta 44
Pregunta
FDG PET/CT findings in anaplastic thyroid cancer can be described by all of the following EXCEPT
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FDG PET/CT defines the local extent of disease and the presence of metastases
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A positive PET/CT scan after therapy is linked with longer survival
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FDG PET/CT have an impact on patients' management
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Intense FDG uptake and volume are prognostic for a bad outcome
Pregunta 45
Pregunta
FDG PET/CT used in patients with suspected and residual/ recurrent gliomas is limited by
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The low 18-F FDG uptake in normal brain tissue
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The high 18-F FDG uptake in normal brain tissue
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The low 18-F FDG uptake in tumour tissue
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The high 18-F FDG uptake in tumour tissue
Pregunta 46
Pregunta
18-F FDG PET imaging is NOT indicated for initial staging of
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Breast cancer
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Hodgkin's lymphoma
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Prostate cancer
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Lung cancer
Pregunta 47
Pregunta
Which of the following statements describing 18-F FDG PET in the diagnostic work-up of patients with melanoma is FALSE
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FDG PET is a standard modality in evaluation of recurrent melanoma
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Melanin content influences lesion detectability by FDG PET
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FDG PET is most valuable in stage III disease
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FDG PET is more accurate for systemic staging than regional staging
Pregunta 48
Pregunta
Ovarian uptake of 18-F FDG in a postmenopausal patient indicates
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A normal finding
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Malignancy
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Pregnancy
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Benign ovarian cyst
Pregunta 49
Pregunta
F-18 FDG focal uptake seen 6 months after completion of radiation therapy should be considered as
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Tumour recurrence
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Normal finding
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Radiation necrosis
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Radiation pneumonitis
Pregunta 50
Pregunta
According to the PERCIST (PET Response Criteria in Solid Tumours) criteria for treatment response evaluation, the changes in SUVs should be assessed as
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Percentage change in the same lesion
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Percentage change in the “hottest” lesion
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Value change in the same lesion
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Value change in the “hottest” lesion
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