LESSON 19 & 20

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Pentose Phosphate System and Glycogen metabolism test
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Pregunta 1

Pregunta
In the Pentose Phosphate System, in which two reactions is NADPH created?
Respuesta
  • - Glucose-6-Phosphate is transformed into 6-Phosphoglucono-δ-lactose - 6-Phosphogluconate is transformed into Ribulose-5-Phosphate
  • - Glucose-6-Phosphate is transformed into 6-Phosphogluconate - 6-Phosphogluconate is transformed into Ribulose-5-Phosphate
  • - Glucose-6-Phosphate is transformed into 6-Phosphogluconate - Ribulose-5-Phosphate is transformed into Xylulose-5-Phosphate
  • - 6-Phosphogluconate is transformed into Ribulose-5-Phosphate - Ribulose-5-Phosphate is transformed into Xylulose-5-Phosphate
  • - Glucose-6-Phosphate is transformed into 6-Phosphogluconate - 6-Phosphogluconate is transformed into 6-Phosphoglucono-δ-lactose

Pregunta 2

Pregunta
The two enzymes present in the non-oxidative face of the Pentose Phosphate System are?
Respuesta
  • Transketolases (able to transfer 2C atoms) and transaldolases (able to transfer 3C atoms)
  • Transaldolases (able to transfer 2C atoms) and transketolases (able to transfer 3C atoms)
  • Transamines (able to transfer 3C atoms) and transaldolases (able to transfer 2C atoms)
  • Transaldolases (able to transfer 3C atoms) and transamines (able to transfer 2C atoms)
  • Any of these

Pregunta 3

Pregunta
Liver will storage glycogen for the fasting state and muscle storage glycogen for the fed state
Respuesta
  • True
  • False

Pregunta 4

Pregunta
What is true about glycogen phosphorylase?
Respuesta
  • 1.) Glycogen phosphorylase can only work in the non-reducing ends
  • 2.) It will stop acting when there are 4 or less residues in a ramification
  • 3.) Glycogen phosphorylase generates a molecule of Glucogen1P and a molecule of glycogen with a residue less from the degradation of a molecule of glycogen
  • Only 1.) and 2.) are true
  • All statements are true

Pregunta 5

Pregunta
What happens in a fasting state?
Respuesta
  • In the liver the predominant form of glycogen phosphorylase is the T state and phosphorylated
  • In the liver the predominant form of glycogen phosphorylase is the R state and diphosphorylated
  • In the muscle the predominant form of glycogen phosphorylase is the R state and phosphorylated
  • In the muscle the predominant form of glycogen phosphorylase is the T state and diphosphorylated
  • Any of these is true

Pregunta 6

Pregunta
How acts AMP in the production of glycogen phosphorylase?
Respuesta
  • It acts as a inhibitor as glucose in liver
  • It acts as an activator as glucose in liver
  • It acts as an inhibitor as ATP and glucose-6P in muscle
  • It acts as an activator in muscle
  • It acts as an activator as ATP and glucose-6P in liver

Pregunta 7

Pregunta
Glucose phosphorylase kinase diphosphorylates glycogen phosphorylase
Respuesta
  • True
  • False

Pregunta 8

Pregunta
Complete the text: In a situation of [blank_start]fasting[blank_end], levels of glucose are [blank_start]low[blank_end]; [blank_start]glucagon[blank_end] is an hormone secreted and it will bind to the receptor that will activate [blank_start]adenylate cyclase[blank_end] that will form AMPc that will activate [blank_start]PKA[blank_end] that is going to phosphorylate glycogen phosphorylase kinase that will phosphorylase [blank_start]glycogen phosphorylase[blank_end].
Respuesta
  • fasting
  • low
  • glucagon
  • adenylate cyclase
  • PKA
  • glycogen phosphorylase

Pregunta 9

Pregunta
Glycogen synthesize is active when is not phosphorylated
Respuesta
  • True
  • False
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