449488
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
|
Creado por gina_evans0312
hace más de 10 años
|
|
Pregunta 1
Pregunta
Alpha helices are a helix-helix structure
Respuesta
- True
- False
Pregunta 2
Pregunta
Which of the following best describes an alpha helix?
Respuesta
-
Ridges are formed by side chains with troughs in between
-
Ridges are formed by the peptide bonds and the amino acid side chains form the troughs
Pregunta 3
Pregunta
Helix-helix packing can be shown by highlighting every _ residues?
Respuesta
-
1st
-
4th
-
3rd
-
2nd
Pregunta 4
Pregunta
Alpha helices must follow particular rules when packing together
Respuesta
- True
- False
Pregunta 5
Respuesta
-
i + 4
-
i + 2
-
i + 3
Pregunta 6
Pregunta
The angle between two packed helices depends on which type of ridges pack into which troughs.
Respuesta
- True
- False
Pregunta 7
Pregunta
The troughs of one alpha helix will be filled by the 'backbone' of another
Respuesta
- True
- False
Pregunta 8
Pregunta
Beta sheets twist slightly _ each other
Respuesta
-
Away from
-
Towards
Pregunta 9
Pregunta
The angle between two beta sheets is approx....?
Respuesta
-
30 degrees
-
60 degrees
-
90 degrees
Pregunta 10
Respuesta
-
Yellow- above plane White- below plane
-
White- above plane Yellow- below plane
-
The amino acids will point in opposite directions
Pregunta 11
Pregunta
The strands of beta sheets are held together by backbone hydrogen bonding
Respuesta
- True
- False
Pregunta 12
Pregunta
The angle between sheets is determined by their...
Respuesta
-
Right handed twist
-
Left handed twist
-
Length
-
Amino acid side chains
Pregunta 13
Pregunta
How are the aa side chains arranged in beta sheets?
Respuesta
-
The amino acid residue side chains of one beta sheet pack between the spaces between side chains on the adjacent beta sheet
-
The amino acids on one beta sheet will have no residue where the other beta sheet has one (they're removed)
-
The amino acids with residues attached will alternate between beta sheets
Pregunta 14
Pregunta
When an alpha helix and a beta sheet pack together, the groove the beta sheet lies in tends to be made by amino acids how far apart?
Respuesta
-
4n
-
6n
-
3n
-
2n
Pregunta 15
Pregunta
Name three things that can be used in protein folding to encourage correct folding?
Respuesta
-
Non-native interactions (as long as they are reversible)
-
Pinching (isolates subdomains for folding)
-
The removal of a domain for folding, before it's re-addition
Pregunta 16
Pregunta
Negative Free Energy is less favorable
Respuesta
- True
- False
Pregunta 17
Pregunta
Concerning entropy- less order is more favorable
Respuesta
- True
- False
Pregunta 18
Pregunta
Which of the following is the equation for the free energy change of a folded protein
Respuesta
-
ΔG = ΔH - TΔS
-
ΔH = ΔG x TΔS
-
TΔS = ΔH + ΔG
Pregunta 19
Pregunta
Hydrogen bonds are the least common type of bond in proteins
Respuesta
- True
- False
Pregunta 20
Pregunta
What's the enthalpy change of a H bond formation?
Respuesta
-
-4 to -30 kJmol
-
-4 to -3 kJmol
-
-40 to -30 kJmol
Pregunta 21
Pregunta
A hydrophobic core in water is entropically favorable
Respuesta
- True
- False
Pregunta 22
Pregunta
Why is hydrophobic cores in water _favorable?
Respuesta
-
They make the water molecules more ordered, decreasing entropy
-
They make the water molecules less ordered, increasing entropy
Pregunta 23
Pregunta
Why do hydrophobic proteins fold?
Respuesta
-
Folded proteins have a reduced surface area, leading to a reduced number of organised water molecules, leading to a lower decrease of entropy
-
Folded proteins have a reduced surface area, leading to a reduced number of organised water molecules, leading to a lower increase of entropy
Pregunta 24
Pregunta
As water ordering decreases, entropy decreases
Respuesta
- True
- False
Pregunta 25
Pregunta
Why is energy needed to maintain the folding of a (hydrophobic) protein (i.e. from hydrogen bonds etc.)?
Respuesta
-
Because the unfolded state of the protein is more entropically favorable than the folded state
-
Because though the folded protein is more entropically favorable, it's folding decreases entropy, which is unfavorable
-
So energy must be produced to maintain the fold
Pregunta 26
Pregunta
Heating denatures a protein because it breaks the bonds required to offset the negative change in entropy caused by the protein folding i.e, it makes ΔH less negative
Respuesta
- True
- False
Pregunta 27
Pregunta
In protein folding, ΔH is negative, and -TΔS is positive
Respuesta
- True
- False
¿Quieres crear tus propios Tests gratis con GoConqr? Más información.