456208
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
How does a retroviruse reproduce?
Respuesta
-
Nuclear fission
-
Reverse transcription onto host genome
-
Binary fission
Pregunta 2
Pregunta
Reverse Transcriptase is vital for RNA retroviruses to replicate
Respuesta
- True
- False
Pregunta 3
Pregunta
The viral protein P is used for what?
Respuesta
-
Packaging signal for making virus particles
-
Capsid protein
-
For genome expression
Pregunta 4
Pregunta
Gag is the gene for envelope proteins
Respuesta
- True
- False
Pregunta 5
Pregunta
Which of the following can be directly translated?
Respuesta
-
+ve sense RNA
-
-ve sense RNA
Pregunta 6
Pregunta
What protein converts viral genomes into a version host cells can transcribe?
Respuesta
-
RNA dependent RNA polymerase
-
DNA dependent RNA polymerase
-
DNA dependent DNA polymerase
-
RNA dependent DNA polymerase
Pregunta 7
Pregunta
The Transcriptosome is the cell repetoire of proteins
Respuesta
- True
- False
Pregunta 8
Pregunta
What is the role of enhancers?
Respuesta
-
To make proteins more efficient
-
To make transcription of a gene more likely
-
To increase cell division
Pregunta 9
Pregunta
Name the types of enhances possible
Respuesta
-
Upstream
-
Adjactent
-
Downstream
-
Internal
Pregunta 10
Pregunta
Introns can make up to 2% of the gene
Respuesta
- True
- False
Pregunta 11
Pregunta
Assuming the middle segment is an intron, what is found at the 5' and 3' splice sites of the intron?
Image:
Splicing (image/png)
Respuesta
-
3'- G-T 5'- Pyrimidine tract
-
5' - G-U 3' - Pyrimidine tract & A-G
-
5' - Pyrimidine tract & A-T 3' G-A
Pregunta 12
Pregunta
How is the 5' intron splice site cleaved?
Respuesta
-
Hydroxyl attack by an adenine
-
Hydroxyl attack by a pyrimidine from the 5' exon splice site
-
The 5' exon splice site attacks the 3' intron splice site
Pregunta 13
Pregunta
The 5' is cleaved and the intron loops on itself- what removes the intron totally?
Respuesta
-
The 5' exon attacks the 3' splice site
-
The 3' exon attacks the 5' splice site
-
The 3' exon attacks itself
Pregunta 14
Pregunta
What is the roles of snRNA?
Respuesta
-
Help for splicosome
-
Resist formation of the splicosome
-
Remove intron after splicing
Pregunta 15
Pregunta
Twintrons are introns within introns
Respuesta
- True
- False
Pregunta 16
Pregunta
Which is spliced out first?
Respuesta
-
Introns
-
Twintrons
Pregunta 17
Pregunta
GpG islands are found near transcriptionally inactive human genes
Respuesta
- True
- False
Pregunta 18
Pregunta
Name the two theories concerning introns
Respuesta
-
Introns are ancient and are gradually being lost
-
Introns are new and are gradually being accumulated
Pregunta 19
Pregunta
What does snoRNA stand for?
Respuesta
-
Small nuclear RNA
-
Small nullifying RNA
-
Small nucleolear RNA
Pregunta 20
Pregunta
snoRNA causes RNA to be acetylated
Respuesta
- True
- False
Pregunta 21
Pregunta
SnoRNA binds to the RNA to be modified
Respuesta
- True
- False
Pregunta 22
Pregunta
What can SnoRNA binding lead to?
Respuesta
-
The modification of bases
-
The destruction of the mRNA
-
The replication of the mRNA
Pregunta 23
Pregunta
There are few miRNA's, but they are very large
Respuesta
- True
- False
Pregunta 24
Pregunta
What is the role of miRNA
Respuesta
-
mRNA silencing
-
Prevent mRNA degredation
-
Inhibit transcription
Pregunta 25
Pregunta
Once the miRNA is transcribed, what structures form?
Respuesta
-
Cruciforms
-
Holliday junctions
-
Stem-loop junctions
Pregunta 26
Pregunta
What enzyme have these miRNA precursors NOT been cut by?
Image:
miRNA_Precursors (image/png)
Respuesta
-
Drosher
-
Dicer
Pregunta 27
Respuesta
-
Binds to 5' end of mRNA to prevent ribosome binding
-
Bind to region between polyA tail and gene, causing cleavage of polyA tail
-
Bind in centre and cause mRNA looping
Pregunta 28
Pregunta
siRNA stands for Short Interfering RNA
Respuesta
- True
- False
Pregunta 29
Pregunta
What is the main role of siRNA?
Respuesta
-
Protection against RNA viruses
-
Protection against oncogenes
-
Protection against bacteria
Pregunta 30
Pregunta
Where and to what does siRNA bind?
Respuesta
-
mRNA of viral genome
-
mRNA of bacterial genome
-
mRNA of human genome
-
On transcribing region
-
On poly-A tail
Pregunta 31
Pregunta
siRNA binds to mRNA in a double stranded form
Respuesta
- True
- False
Pregunta 32
Pregunta
Which of the following could be used as a gene therapy?
Respuesta
-
miRNA
-
siRNA
-
snRNA
-
snoRNA
Pregunta 33
Pregunta
This RNA gene therapy works by making a dsRNA version of a gene in the cell; this will be cleaved to siRNA which will destroy ALL mRNA for that gene
Respuesta
- True
- False
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