Leucocyte Pathologies

Descripción

(Leukocytes) Haematology and Anatomy Test sobre Leucocyte Pathologies, creado por gina_evans0312 el 09/01/2014.
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Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312 hace más de 10 años
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Resumen del Recurso

Pregunta 1

Pregunta
In Flow Cytometry, cell size is measured as they pass through laser beams
Respuesta
  • True
  • False

Pregunta 2

Pregunta
Why is this area left?
Respuesta
  • Excludes cells with low CD45
  • Excludes small cells
  • Excludes cells too large to pass through

Pregunta 3

Pregunta
In Flow Cytometry, the Ig tested for varies depending on which cell you're measuring
Respuesta
  • True
  • False

Pregunta 4

Pregunta
For which cell would you use an alkaline reagent?
Respuesta
  • Eosinophils
  • Basophils
  • Monocytes

Pregunta 5

Pregunta
Normal range of W.B.C's is 4-11 (x10^7/l)
Respuesta
  • True
  • False

Pregunta 6

Pregunta
What is to be expected in a Settling test from a leukaemia patient?
Respuesta
  • Thinker plasma layer
  • Thicker buffy coat layer
  • Thicker erythrocyte layer

Pregunta 7

Pregunta
Why is a strong lysing solution added to a W.B.C count?
Respuesta
  • Remove R.B.C's
  • Remove platelets

Pregunta 8

Pregunta
Like R.B.C's, W.B.C's are counted using current impedence
Respuesta
  • True
  • False

Pregunta 9

Pregunta
What are the two populations (peaks) shown here?
Respuesta
  • Lymphocytes
  • Monocytes
  • Nutraphils
  • All others

Pregunta 10

Pregunta
What two things are mapped in D.I.F.F?
Respuesta
  • Size
  • Shape
  • Granularity
  • Markers

Pregunta 11

Pregunta
What cells are being pointed at on the graph?
Respuesta
  • Netraphils
  • Monocytes
  • Lymphocytes

Pregunta 12

Pregunta
Cellpack & Stromatolyers 3D do what?
Respuesta
  • Protect W.B.C's
  • Speed R.B.C's lysis

Pregunta 13

Pregunta
List some causes of Neutropenia
Respuesta
  • Overwhelming bacterial/viral/funal/parasitic infections
  • Anti-cancer drugs
  • Irradiation
  • Aplastic Anaemia

Pregunta 14

Pregunta
Chronic infection/inflammation and increased cytokinase can lead to high...
Respuesta
  • Monocytes
  • Eosinophils
  • Basophils

Pregunta 15

Pregunta
Basophilia is caused by
Respuesta
  • Leukaemias
  • Allergic recations

Pregunta 16

Pregunta
Eosinophilia is caused by allergic infections, parasitic infections and drug hypersensitivity
Respuesta
  • True
  • False

Pregunta 17

Pregunta
Name some causes of Lymhpocytopenia
Respuesta
  • AIDs
  • Carcinoma
  • Renal failure
  • Vigerous exercise/Smoking

Pregunta 18

Pregunta
Name the three tests done for any Leucocytic disorder
Respuesta
  • Flow Cytometry
  • Full blood count & DFF
  • NAP test
  • Paul Bunnell Test
  • Morphology

Pregunta 19

Pregunta
Why does Clonality indicate a severe pathology?
Respuesta
  • A single cell type is proliferating massively
  • Shows a lack of diversity across leucocytes
  • Shows massive infection

Pregunta 20

Pregunta
What markers do you test for when looking for Clonality?
Respuesta
  • Kappa/lambda markers
  • CD4/CD8
  • Alpha, beta & gamma

Pregunta 21

Pregunta
In AIDS, you perform flow cytometry for Kappa/Lambda markers
Respuesta
  • True
  • False

Pregunta 22

Pregunta
The Paul Bunnel test is done for...
Respuesta
  • Viruses
  • Fungi
  • Bacteria

Pregunta 23

Pregunta
Name the cause of Haematological Malignancies
Respuesta
  • Genetics
  • Drugs
  • Irradiation
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