514671
Pregunta 1
Pregunta
Which of the following is NOT a major mast cell mediator?
Respuesta
-
Heparin
-
Arachadonic acid
-
Platelet activating factor
-
Neutrophilic chemotactic factor
-
Lymphocytic chemotactic factor
-
Serine proteases
Pregunta 2
Pregunta
Which of the following are effects of histamine? Check all that apply.
Respuesta
-
Stimulates nitric oxide production (potent vasodilator)
-
Enhances leukocyte chemotaxis
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Produces arachadonic acid metabolites
-
Stimulates smooth muscle contraction (bronchi, small intestines, pulmonary vasoconstriction)
-
Causes decreased vascular permeability
Pregunta 3
Pregunta
Leukotrienes are metabolites of arachadonic acid that are potent bronchoconstrictors.
Respuesta
- True
- False
Pregunta 4
Pregunta
Which of the following pairings is INCORRECT?
Respuesta
-
Serine proteases- destroy nearby cells and activate complement
-
Kinins- stimulate pain receptors
-
Cytokines- regulate storage and release of vasoactive mediators
-
Heparin- acts as anticoagulant
Pregunta 5
Pregunta
Generally, the onset of anaphylaxis is not related to severity of signs.
Respuesta
- True
- False
Pregunta 6
Pregunta
Localized anaphylaxis has evidence of generalized mediator release restricted to cutaneous findings alone. Which of the following is NOT one of these findings?
Respuesta
-
Erythema
-
Pruritis
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Urticaria
-
Angioedema
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These are all appropriate cutaneous findings, Karah. Get it together!
Pregunta 7
Pregunta
Which of the following are true regarding epinephrine for systemic anaphylaxis? Check all that apply.
Respuesta
-
Blocks effects of mediators
-
Reduces further mast cell degranulation
-
Increases cardiac output
-
Promotes bronhoconstriction
-
Peripheral vasodilation
-
IV dose of 1 mg/ml concentration is 0.05-0.1 ml/10 lbs
Pregunta 8
Pregunta
When treating anaphylaxis with crystalloid IV fluids it is important that systolic blood pressure is maintained at >80 mmHg.
Respuesta
- True
- False
Pregunta 9
Pregunta
Which of the following is the anti-inflammatory dose of dexamethasone SP for treatment of anaphylaxis?
Respuesta
-
0.1-0.2 mg/kg IV
-
0.5-1 mg/kg IV
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0.1-0.2 mg/kg IM
-
0.5-1 mg/kg IM
Pregunta 10
Pregunta
The IM dose of diphenhydramine for systemic anaphylaxis is 1-2 mg/kg.
Respuesta
- True
- False
Pregunta 11
Pregunta
What drug can we use to manage persistent bradycardia with systemic anaphylaxis?
Respuesta
-
Atropine, 0.02-0.04 mg/kg IV, IM
-
Atropine, 0.2-0.4 mg/kg IV, IM
-
Dobutamine, 5-10 mcg/kg/min IV (constant rate infusion)
-
Dobutamine, 0.5-1 mcg/kg/min IV (constant rate infusion)
Pregunta 12
Pregunta
Aminophylline/theophyylline is a bronchodilator given IM or IV (slowly) at 4-8 mg/kg.
Respuesta
- True
- False
Pregunta 13
Pregunta
What is the dose for oral diphenhydramine for treatment of localized anaphylaxis?
Respuesta
-
1 mg/lb q 8 hrs until all signs are clear
-
1 mg/kg q 8 hrs until all signs are clear
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