5652920
Descripción
Test por Med Student , actualizado hace más de 1 año
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Creado por Med Student
hace más de 8 años
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Pregunta 1
Pregunta
A blood group has both A and B antigens but no antibodies, It is
Respuesta
-
B
-
AB
-
O
-
A
Pregunta 2
Pregunta
A compound formed in an organism for inhibiting growth of another organism is
Respuesta
-
Antigen
-
Antibody
-
Antibiotic
-
Antiallergic
Pregunta 3
Pregunta
A disease due to allergic reaction is
Respuesta
-
Enteric fever
-
Yellow fever
-
Hay fever
-
Trench fever
Pregunta 4
Pregunta
Which is involved in body defense?
Respuesta
-
Neutrophils
-
Macrophages
-
Lymphocytes
-
All the above
Pregunta 5
Pregunta
A doctor suggested to a couple not to have more than one child because of
Respuesta
-
Rh+ male Rh- female
-
Rh- male Rh+ female
-
Rh+ male Rh+ female
-
Rh- male Rh- female
Pregunta 6
Pregunta
A molecule that produces an immune response is
Respuesta
-
Antigen
-
Antibody
-
Carcinogen
-
Mutagen
Pregunta 7
Pregunta
A noninfectious unnatural and unusual reaction to a substance or condition is
Respuesta
-
Immunity
-
Allergy
-
Infection
-
Toxin
Pregunta 8
Pregunta
A person is injected with gammaglobulin against hepatitis B. It is
Respuesta
-
Artificially acquires passive immunity
-
Artificially acquires active immunity
-
Naturally acquires active immunity
-
Naturally acquires passive immunity
Pregunta 9
Pregunta
Acquired immunity as developed after vaccination or infection is found in
Respuesta
-
Vertebrates only
-
Invertebrates as well as vertebrates
-
Plants
-
All the above
Pregunta 10
Pregunta
Acquired immunity is found in
Respuesta
-
Invertebrates
-
Vertebrates
-
Some invertebrates
-
Both vertebrates and invertibrates
Pregunta 11
Pregunta
Active immunity is due to
Respuesta
-
Suppressor T-cells
-
killer T-cells
-
Memory cells
-
Helper T-cells
Pregunta 12
Pregunta
Active immunity means
Respuesta
-
Resistance developed before disease
-
Resistance developed after disease
-
Increased heart beat
-
Increased flow of blood
Pregunta 13
Pregunta
AIDS is caused by
Respuesta
-
RNA virus
-
DNA virus
-
Herpes virus
-
Hepatitis virus
Pregunta 14
Pregunta
An example of innate immunity is
Respuesta
-
T-lymphocytes
-
B-lymphocyte
-
Neutrophils
-
Thyroid cells
Pregunta 15
Pregunta
An insect bite may result in inflammation of that spot. It is triggered by alarm chemicals such as
Respuesta
-
Histamine and dopamine
-
Histamine and kinins
-
Interferon and opsonin
-
Interferons and histones
Pregunta 16
Pregunta
An Rh- individual receives Rh+ blood. The recipient becomes
Respuesta
-
Sterlite
-
Dead
-
No reaction
-
Isoimmunised
Pregunta 17
Pregunta
Which of the following are secondary lymphoid organs?
Respuesta
-
Spleen
-
Lymph Nodes
-
Thymus
-
Bone Marrow
-
Lymph Vessels
Pregunta 18
Pregunta
IgG consists of
Respuesta
-
2 light chains and two heavy chains joined by di-sulphide bond (H2L2)
-
2 light chains and two heavy chains joined by hydrogen bond (H2L2)
-
2 light chains and a heavy chain joined by di-sulphide bond (H1L2)
-
a light chain and two heavy chains joined by di-sulphide bond (H2L1)
Pregunta 19
Pregunta
Which is the Ig that first reaches the site of infection?
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 20
Pregunta
Which is the largest Ig?
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 21
Pregunta
Which of the following statements are true regarding IgM?
Respuesta
-
IgM is a pentamer and is the largest Ig and called as ‘natural antibody’
-
IgM exists as monomer on B-cell surface
-
IgM is involved in early primary immune response
-
all of these
Pregunta 22
Pregunta
Which of the following statements are true?
Respuesta
-
IgM is involved in primary immune response
-
IgG is involved in primary immune response
-
Both IgM and IgG are involved in primary immune response
-
IgG is involved only in secondary immune response
Pregunta 23
Pregunta
The antibody present in secretions like tears, saliva, colostrum is
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 24
Pregunta
The primary Ig of exocrine secretions is
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 25
Pregunta
Antibodies are:
Respuesta
-
proteins
-
glycoproteins
-
carbohydrates
-
nucleic acid
Pregunta 26
Pregunta
The antigen binding site on an antibody is called:
Respuesta
-
endotope
-
paratope
-
epitope
-
antitope
Pregunta 27
Pregunta
An antibody has
Respuesta
-
2 Fab regions and an Fc region
-
an Fab region and an Fc region
-
2 Fab regions and 2 Fc regions
-
many Fab regions and many Fc regions
Pregunta 28
Pregunta
The hypervariable region resides in the
Respuesta
-
N terminal region of light chain
-
N-terminal region of light and heavy chain
-
C-terminal region of light chain
-
C-terminal region of light chain and heavy chain
Pregunta 29
Pregunta
Fab stands for
Respuesta
-
fragment antibody binding
-
fragment antigen binding
-
fragment antibody or antigen binding
-
fragment affinity binding
Pregunta 30
Pregunta
Which of the following statement is true regarding Fc region?
Respuesta
-
fragment crystalisation and is the constant region
-
fragment constant and is the variable region
-
fragment crystalisation and is the variable region
-
fragment crystalisation and has both variable and constant region
Pregunta 31
Pregunta
Fab region:
Respuesta
-
has a hypervariable region that binds with antibody
-
has a hypervariable region that binds with antigen
-
has a hypervariable region that binds with other immune cells
-
all of these
Pregunta 32
Pregunta
Fc region is involved in
Respuesta
-
cell surface receptor binding
-
complement activation
-
determining diffusivity of antibody molecule
-
all of these
Pregunta 33
Pregunta
The ability of antigen to stimulate antibody production is called
Respuesta
-
Affinity
-
Antigenicity
-
Elicitation
-
none of these
Pregunta 34
Pregunta
Clearance of antigens by antibodies involve
Respuesta
-
neutralization and agglutination
-
opsonisation and complement activation
-
precipitation
-
all of these
Pregunta 35
Pregunta
The two identical light chains of an antibody belongs to
Respuesta
-
kappa only
-
lambda only
-
lambda or kappa
-
none of these
Pregunta 36
Pregunta
Antigens can be
Respuesta
-
proteins
-
carbohydrates
-
nucleic acids
-
all of these
Pregunta 37
Pregunta
A molecule that reacts with specific antibody but is not immunogenic by itself is called
Respuesta
-
carrier
-
antigen
-
hapten
-
immunogen
Pregunta 38
Pregunta
Haptens are immunogenic upon binding covalently to a carrier protein how?
Respuesta
-
covalently to a carrier protein
-
covalently to an antibody
-
covalently to a paratope
-
none of these
Pregunta 39
Pregunta
Haptens cannot activate T cell or B cells due to:
Respuesta
-
its low molecular weight antigens arbuscules
-
its inability to bind to MHC
-
both a and b
-
none of these
Pregunta 40
Pregunta
Which of the following is a hapten?
Respuesta
-
Cyanide
-
Paracetamol
-
Penicillin
-
None of these
Pregunta 41
Pregunta
An incomplete antigens
Respuesta
-
are also called as haptens
-
are immunogenic upon binding covalently to a carrier protein
-
cannot induce antibody production by itself
-
all of the above
Pregunta 42
Pregunta
The second most abundant Ig is
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 43
Pregunta
The most effective Ig is:
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 44
Pregunta
IgM is a
Respuesta
-
pentamer with 10 antigen binding sites
-
tetramer with 8 antigen binding sites
-
monomer with 2 antigen binding sites
-
dimer with 4 antigen binding sites
Pregunta 45
Pregunta
The Ig that mediates allergic reaction is
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 46
Pregunta
The Ig involved in host defence against parasitic infection (helminths)
Respuesta
-
IgM
-
IgG
-
IgA
-
IgE
Pregunta 47
Pregunta
The bonds involved in antigen-antibody interactions are
Respuesta
-
weak hydrogen bonds and vanderwalls forces
-
strong covalent bonds
-
strong di- sulphide bonds
-
all of these
Pregunta 48
Pregunta
Which of the following statement is true?
Respuesta
-
all immunogens are antigens but all antigens are not immunogens
-
all immunogens are antigens and all antigens are immunogens
-
all immunogens are not antigens but all antigens are immunogens
-
all immunogens are proteins and all proteins are immunogens
Pregunta 49
Pregunta
Which of the statements are true regarding antigen?
Respuesta
-
generally self-molecules and molecules with low molecular weight are non-immunogenic
-
an antigen generally has many epitopes
-
heteropolymers are more immunogenic than homopolymers
-
all of these
Pregunta 50
Pregunta
The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as
Respuesta
-
transplantation
-
replacement therapy
-
repair and replacement
-
none of these
Pregunta 51
Pregunta
The transfer of individuals own tissue to another part of the body is called
Respuesta
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Pregunta 52
Pregunta
The transfer of tissue between genetically identical individuals (like twins) is called
Respuesta
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Pregunta 53
Pregunta
The transfer of tissue between individuals of different species is called
Respuesta
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Pregunta 54
Pregunta
The transfer of tissue between genetically different individuals of same species is called
Respuesta
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Pregunta 55
Pregunta
Which of the following has the maximum transplantation success rate?
Respuesta
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Pregunta 56
Pregunta
The major molecules responsible for rejection of transplant is
Respuesta
-
B cells
-
T cells
-
MHC molecule
-
Antibodies
Pregunta 57
Pregunta
Which of the following statements are true regarding transplantation?
Respuesta
-
The compatibility of MHC proteins of donor and recipient will determine the success of transplantation
-
MHCs are just like fingerprints and all nucleated cells possess this fingerprint
-
The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.
-
all of these
Pregunta 58
Pregunta
In humans, MHC is called as
Respuesta
-
Human MHC
-
Homo MHC
-
Human leucocyte antigen (HLA)
-
All of the above
Pregunta 59
Pregunta
The genes for HLA proteins are clustered in the major histocompatibility complex located
Respuesta
-
on the short arm of chromosome 6
-
on the long arm of chromosome 6
-
on the short arm of chromosome 10
-
on the long arm of chromosome 10
Pregunta 60
Pregunta
The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donor and recipient is called
Respuesta
-
MHC matching
-
MHC typing
-
tissue typing
-
blood HLA test
Pregunta 61
Pregunta
MHC class I is a cell surface molecule present on
Respuesta
-
B cells
-
All nucleated cells
-
APCs
-
T cells
Pregunta 62
Pregunta
MHC class II is a cell surface molecule present on
(most correct ans.)
Respuesta
-
B cells
-
All nucleated cells
-
APCs
-
T cells
Pregunta 63
Pregunta
Which of the following statements are true regarding complement activation?
Respuesta
-
lysis of pathogen, tumor cells and allografts
-
production of mediators that attracts neutrophils to the site of inflammation
-
opsonization
-
all of these
Pregunta 64
Pregunta
Complement system is involved in
Respuesta
-
specific defence
-
non-specific defence
-
both a and b
-
none of these
Pregunta 65
Pregunta
Allergy to penicillin is an example of
Respuesta
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Pregunta 66
Pregunta
Type IV hypersensitivity is also called as:
Respuesta
-
immediate hypersensitivity
-
delayed hypersensitivity
-
cytotoxic hypersensitivity
-
immune complex hypersensitivity
Pregunta 67
Pregunta
The most common class of antibody involved in type II hypersensitivity is
Respuesta
-
IgG
-
IgM
-
IgE
-
IgD
Pregunta 68
Pregunta
T helper cell mediated hypersensitivity is:
Respuesta
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Pregunta 69
Pregunta
Type III hypersensitivity is triggered by:
Respuesta
-
Mast cells and IgE
-
K cells and IgG
-
Deposition of antigen antibody complexes
-
Th cells
Pregunta 70
Pregunta
Autoimmune hemolytic anemia (AHA) is an example of
Respuesta
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Pregunta 71
Pregunta
K cells and IgG mediated hypersensitivity is
Respuesta
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Pregunta 72
Pregunta
Antibody dependent cytotoxicity is associated with
Respuesta
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Pregunta 73
Pregunta
Allergies to sea foods, eggs etc is an example of
Respuesta
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Pregunta 74
Pregunta
Humoral immunity is mediated by
Respuesta
-
B cells
-
macrophages
-
both a and b
-
phagocytes
Pregunta 75
Pregunta
Humoral immunity is also called as
Respuesta
-
antibody mediated immunity
-
non-specific immune response
-
antigen mediated immunity
-
all of these
Pregunta 76
Pregunta
B cell has receptor on its surface which is
Respuesta
-
monomeric IgM
-
dimeric IgM
-
monomeric IgG
-
B cell receptor
Pregunta 77
Pregunta
B cells upon activation by antigens
Respuesta
-
undergo clonal expansion followed by clonal selection
-
divides continuously
-
undergo clonal selection followed by clonal expansion
-
secrete antibodies
Pregunta 78
Pregunta
B cells differentiates to form
Respuesta
-
plasma cells only
-
effector cells only
-
plasma cells and memory B cells
-
none of these
Pregunta 79
Pregunta
Which of the following statement is incorrect regarding plasma cells?
Respuesta
-
Plasma cells are the effector cells
-
Plasma cells secretes antibodies
-
The precursor of plasma cell is B cell
-
Plasma cell has surface receptors
Pregunta 80
Pregunta
Origin and maturation of B cells takes place at
Respuesta
-
lymph nodes
-
bone marrow
-
thymus
-
spleen
Pregunta 81
Pregunta
The function of memory B cell is
Respuesta
-
antibody production
-
immunologic memory
-
regulated antibody production
-
none of these
Pregunta 82
Pregunta
Generally antibodies produced against a pathogen is
Respuesta
-
monoclonal
-
homogenous
-
polyclonal
-
all of same specificity
Pregunta 83
Pregunta
Antibodies produced by plasma cells are
Respuesta
-
specific
-
produced against the epitope that triggered B cell activation
-
both a and b
-
diverse
Pregunta 84
Pregunta
Antibodies clear out antigens by
Respuesta
-
neutralization
-
precipitation
-
agglutination
-
all of these
Pregunta 85
Pregunta
Antibodies are
Respuesta
-
opsonins
-
lipoproteins
-
serum phagocytes
-
none of these
Pregunta 86
Pregunta
Any substance that promotes phagocytosis of antigens by binding to them are called as
Respuesta
-
interleukins
-
macrophages
-
phagocytes
-
opsonins
Pregunta 87
Pregunta
The phenomenon of selective proliferation of B cells in response to their interaction with the antigen is called
Respuesta
-
clonal expansion
-
monoclonal selection
-
clonal proliferation
-
clonal selection
Pregunta 88
Pregunta
The specific targeted responses constitute the third line of defense in response to an infectious agent and is called as
Respuesta
-
third line of defence
-
adaptive immunity
-
acquired immunity
-
all of these
Pregunta 89
Pregunta
The characteristics of adaptive immunity include
Respuesta
-
specificity
-
immunologic memory
-
discrimination of self from non self molecules
-
all of these
Pregunta 90
Pregunta
Which of the cells are involved in adaptive immunity?
Respuesta
-
B cells and T cells
-
B cells only
-
T cells only
-
macrophages and NK cells
Pregunta 91
Pregunta
T cell mediates
Respuesta
-
humoral immunity
-
non-specific defence
-
cell mediated immunity
-
none of these
Pregunta 92
Pregunta
The ratio of T cells to B cells is
Respuesta
-
3:1
-
1:3
-
1:1
-
1:2
Pregunta 93
Pregunta
T cells and B cells are originated in
Respuesta
-
spleen
-
thymus
-
bone marrow
-
lymph nodes
Pregunta 94
Pregunta
Injection of anti-venom against snake bite is an example of
Respuesta
-
active immunity
-
passive immunity
-
non-specific immunity
-
phagocytic immunity
Pregunta 95
Pregunta
Which of the following statements are true regarding adaptive immunity?
Respuesta
-
prior exposure to antigen is essential
-
prior exposure to antigen is not essential
-
it is a non-specific defence mechanism
-
macrophages are the major cells involved
Pregunta 96
Pregunta
Active immunity involves
Respuesta
-
contact with foreign antigens
-
immunologic memory
-
slow primary response
-
all of the above
Pregunta 97
Pregunta
Active immunity is produced by
Respuesta
-
clonal selection
-
clonal expansion
-
both a and b
-
all of these
Pregunta 98
Pregunta
Cells involved in adaptive immunity or acquired immunity or specific defense include
Respuesta
-
T cells
-
B cells
-
Antigen presenting cells
-
All of these
Pregunta 99
Pregunta
Plasma cells are secreted by
Respuesta
-
T cells
-
B cells
-
Antigen presenting cells
-
Macrophages
Pregunta 100
Pregunta
The characteristics of passive immunity include
Respuesta
-
immediate relief
-
no immunologic memory
-
resistance for a short period only
-
all of these
Pregunta 101
Pregunta
Immunologic memory is provided by
Respuesta
-
B cells
-
T cells
-
Both a and b
-
Phagocytes
Pregunta 102
Pregunta
A method for cell sorting based on the surface antigens (markers) which react specifically with fluorescent-labelled antibodies is called
Respuesta
-
Flowcytometry
-
Immunofluorescent technique
-
Immunoelectrophoresis
Pregunta 103
Pregunta
A technique in which tissues and cells are examined by a fluorescent light microscope using fluorescent-labeled antibodies is called
Respuesta
-
Immunofluorescent technique
-
Flowcytometry
-
Immunoelectrophoresis
Pregunta 104
Pregunta
A technique for the identification of proteins in serum or other fluid by electrophoresis and subsequent immunodiffusion is called
Respuesta
-
Immunoelectrophoresis
-
Flowcytometry
-
Immunofluorescent technique
Pregunta 105
Pregunta
Classical pathway of complement system is activated by
Respuesta
-
antibody-antigen complexes
-
antigen
-
antigenic peptides
-
antigens bound to MH
Pregunta 106
Pregunta
Alternate pathway of complement system is activated by
Respuesta
-
antibody-antigen complexes
-
antigen
-
microorganisms or its toxins
-
antigens bound to MHC
Pregunta 107
Pregunta
Classical pathway of complement system is involved in
Respuesta
-
specific defence
-
adaptive immunity
-
both a and b
-
non-specific defence
Pregunta 108
Pregunta
Alternate pathway of complement system is involved in
Respuesta
-
non-specific defence
-
innate immunity
-
both a and b
-
adaptive immunity
Pregunta 109
Pregunta
Complement system
Respuesta
-
consists of 20 serum proteins
-
serum proteins acts as biological cascade
-
both a and b
-
are set of antibodies
Pregunta 110
Pregunta
Complement system is involved in
Respuesta
-
specific defence
-
non-specific defence
-
both a and b
-
none of these
Pregunta 111
Pregunta
Kupffer cells are macrophages found on
Respuesta
-
lung
-
bone
-
nephrons
-
liver
Pregunta 112
Pregunta
Antiviral glycoproteins released by living cells in response to viral attack and induce a viral resistant state to neighboring cells is called as
Respuesta
-
natural killer cells
-
complement system
-
phagocytes
-
interferons
Pregunta 113
Pregunta
Newborns get their antibodies from mothers milk. This is an example of
Respuesta
-
Naturally acquired active immunity
-
Artificially acquired active immunity
-
Naturally acquired passive immunity
-
Artificially acquired passive immunity
Pregunta 114
Pregunta
Which of the following is the site of T cell maturation?
Respuesta
-
Bone marrow
-
Thymus
-
Spleen
-
Appendix
Pregunta 115
Pregunta
Primary lymphoid organs include
Respuesta
-
Thymus and spleen
-
Thymus and bone marrow
-
Thymus, bone marrow and spleen
-
Thymus, bone marrow, spleen and lymph nodes
Pregunta 116
Pregunta
The major chemical messenger involved in hypersensitivity is
Respuesta
-
interferons
-
histamines
-
lymphokines
-
interleukines
Pregunta 117
Pregunta
HIV attacks:
Respuesta
-
macrophages
-
B cells
-
T cytotoxic cells
-
T helper cells
Pregunta 118
Pregunta
Regarding the inflammatory response:
Respuesta
-
Tissue swelling is the first stage of the inflammatory response.
-
Mast cells secrete chemotactic agents that attract lymphocytes
-
Macrophages secrete vasoactive materials during the inflammatory response
-
The inflammatory response can be triggered by antibody binding to the surface of micro-organisms.
Pregunta 119
Pregunta
Natural killer cells only destroy cells infected with a virus.
Respuesta
- True
- False
Pregunta 120
Pregunta
The antigens below are on your erythrocytes (red blood cells) which antibodies would you expect to find in the serum
1/ A- [blank_start]B[blank_end]
2/ B- [blank_start]A[blank_end]
3/ O- [blank_start]AB[blank_end]
Respuesta
-
B
-
A
-
AB
-
O
-
A
-
B
-
AB
-
O
-
AB
-
O
-
A
-
B
Pregunta 121
Pregunta
Fill in the Blanks (No - symbol needed)
1/ Precursor Chain + [blank_start]L fucose[blank_end]= H-Antigen
2/ H-Antigen + [blank_start]N acetylgalactosamine[blank_end]= A-Antigen
3/ H-Antigen + [blank_start]D Galactose[blank_end]= B-Antigen
Respuesta
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L fucose
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N acetylgalactosamine
-
D Galactose
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