630602
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
B Cells recognise native antigens, T cells recognise processed antigens
Respuesta
- True
- False
Pregunta 2
Pregunta
Which of the following are NOT professional antigen presenting cells?
Respuesta
-
Neutrophils
-
Macrophages
-
Dendritic cells
Pregunta 3
Pregunta
CD8 T-cells recognise which MHC complex?
Respuesta
-
MHCI
-
MHCII
Pregunta 4
Pregunta
CD4 is for the detection of virally infected cells
Respuesta
- True
- False
Pregunta 5
Pregunta
CD4 cells recognise MHCII, which uses which Antigen processing system?
Respuesta
-
Endosomal
-
Endogenous
-
Endomal
Pregunta 6
Pregunta
Cells with MHCI present using the endogenous AP system
Respuesta
- True
- False
Pregunta 7
Pregunta
T- cells cannot recognise soluble, native antigens
Respuesta
- True
- False
Pregunta 8
Pregunta
Put the following steps in the correct order- A (Antigen-MHC Complex Formation), B (Uptake), C (Presentation) and D (Degredation
Respuesta
-
B-D-A-C
-
A-B-D-C
-
A-C-B-D
Pregunta 9
Pregunta
Which of the following definitions is incorrect?
Respuesta
-
Uptake- picking up of the antigen from surrounding fluid
-
Degredation- total digestion of the antigen
-
Presentation- movement of the complex to the cell surface
Pregunta 10
Pregunta
Endosomal Pathway- What is it for?
Respuesta
-
Processing of extracellular antigens picked up by antigen presenting cells
-
Processing of cytosolic viral antigens
Pregunta 11
Pregunta
Endosomal Pathway- Uses the MHCI complex
Respuesta
- True
- False
Pregunta 12
Pregunta
Endosomal Pathway- The extracellular antigen is picked up by phagocytosis
Respuesta
- True
- False
Pregunta 13
Pregunta
Endosomal Pathway- How is picking up of the antigen mediated?
Respuesta
-
Receptor mediated
-
Compliment mediated
-
Hormone mediated
Pregunta 14
Pregunta
Endosomal Pathway- The antigen containing endosome only binds to the MCHII containing endosome after partial digestion
Respuesta
- True
- False
Pregunta 15
Pregunta
Endosomal Pathway- How is the active site of MHCII covered in the cell?
Respuesta
-
Covered by an invariant 'cap'
-
The two parts are connect by a subunit that must be removed
-
Receptor surface is bound to the endosome envelope
Pregunta 16
Pregunta
Endosomal Pathway- The cover of the MHC complex is called a CLIP
Respuesta
- True
- False
Pregunta 17
Pregunta
Endosomal Pathway- How is the processed antigen added to the MHCII complex?
Respuesta
-
Acessory proteins swap the CLIP for the peptide when the two vesicles fuse
-
Acessory proteins remove the MHCII from the envelope when the two vesicles fuse
-
Acessory proteins remove the subunit connecting the two halves when the two vesicles fuse
Pregunta 18
Pregunta
Endogenous Pathway- Main use is for what?
Respuesta
-
Viral antigen processing
-
Professional pesentation of antigens
Pregunta 19
Pregunta
Endogenous Pathway uses MHCII
Respuesta
- True
- False
Pregunta 20
Pregunta
Endogenous Pathway- How are cytosolic antigens processed?
Respuesta
-
By the TCR
-
By MHCI
-
By cytosolic proteases
Pregunta 21
Pregunta
Endogenous Pathway- Digested peptides are moved into the Golgi by what?
Respuesta
-
Transporter Associated with Antigen Processing (TAP 1&2)
-
Transporter Associated with Antigen Digestion (TAD 1&2)
-
Transporter Associated with Antigen Presentation (TAP 1&2)
Pregunta 22
Pregunta
In the Golgi the processed peptide is bound to MHCI and they complex is loaded into a vesicle for transport to the cell membrane
Respuesta
- True
- False
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