Pathoanatomy - Cell Injury MCQ's

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Pathoanatomy - Cell Injury MCQ's
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Pregunta 1

Pregunta
Indicate in which of the shown organs develops a coagulative necrosis
Respuesta
  • Brain
  • Kidney
  • Myocardium
  • Intestine

Pregunta 2

Pregunta
Indicate in which of the listed organs liquefactive necrosis occurs:
Respuesta
  • Liver
  • Kidney
  • Brain
  • Myocardium

Pregunta 3

Pregunta
The outcome of anemic brain attack may be:
Respuesta
  • Cyst
  • Pseudocyst
  • Gliosis
  • Scarring

Pregunta 4

Pregunta
Caseous necrosis is typical for:
Respuesta
  • Specific inflammation
  • TBC
  • Enzyme fat necrosis
  • Chronic pyelonephritis

Pregunta 5

Pregunta
At autopsy in the temporal lobe of the brain is found a cyst with a diameter of 2cm, with smooth walls filled with a clear pale yellow liquid. Specify what it is:
Respuesta
  • Abscess of the brain
  • Pseudocyst of the brain
  • Tumor
  • Encephalitis

Pregunta 6

Pregunta
Is formalin a suitable fixative for proof of neutral fat with Sudan 3?
Respuesta
  • Yes
  • No

Pregunta 7

Pregunta
Which stains are used for detection of amyloid?
Respuesta
  • Sudan 3
  • Congorot
  • Iodine solution + Sulfuric acid (H2So4)
  • Thiophlavin S - UV

Pregunta 8

Pregunta
The term "patognomonic change" means?
Respuesta
  • Changes with unclear origin
  • Paradoxal changes
  • Sufficient for diagnosis changes
  • Diffuse inflammatory changes

Pregunta 9

Pregunta
It is recommended that the material for the biopsy should be taken:
Respuesta
  • With electric knife
  • From central area of lesion
  • From periphery of the lesion
  • Entirely Removed

Pregunta 10

Pregunta
Hyaline-drop Degeneration is:
Respuesta
  • Celluar
  • Extracellular
  • Protein
  • Carbohydrate

Pregunta 11

Pregunta
Brown induration of the lung is seen in:
Respuesta
  • Acute left heart failure
  • Chronic left heart failure
  • Lobar pneumonia
  • Chronic right heart failure

Pregunta 12

Pregunta
What is true?
Respuesta
  • In Pompe disease accumulation cholesterol in the liver
  • In von Gierke glycogen accumulates primarily in the myocardium
  • Tay-Sacks disease is known as the amavrotic idioty
  • in Gaucher disease is observed deposition of cerebrozides

Pregunta 13

Pregunta
What is true?
Respuesta
  • Apoptosis is programmed cell death, necrosis - end stage degenerative processes
  • Apoptosis affects individual cells, necrosis - large areas
  • Necrosis induces an inflammatory response, apoptosis does not lead to tissue reaction
  • Apoptosis is a reversible process, and necrosis can be stopped

Pregunta 14

Pregunta
With regard to the completeness of the survey which is the number of biopsies needed to be taken in the course of a routine autopsy?
Respuesta
  • 5
  • 10
  • 20
  • 0

Pregunta 15

Pregunta
Optimal for routine biopsy survey are:
Respuesta
  • Tissue fragment with a size of 1cm, immersed in a double volume of fixative for 3 hours
  • Tissue fragments with size 4cm - 20 times the volume of the retainer, for 8 hours
  • In freezing microtome regardless of the size of the tissue
  • Tissue cubes with size 1cm at 20 times larger volume of container for 24 hours

Pregunta 16

Pregunta
Proof of lipids is done by:
Respuesta
  • Freezing microtom
  • Paraffin method
  • Alcohol fixation
  • Staining with Sudan 3

Pregunta 17

Pregunta
For proof of carbohydrates is appropriate to use:
Respuesta
  • Freeze microtom
  • Formalin fixation
  • Alcohol fixation
  • PAS staining

Pregunta 18

Pregunta
Frozen section serves for:
Respuesta
  • Intraoperative histological diagnosis
  • Cytologic diagnosis
  • Detection of amyloid
  • Demonstration of lipids

Pregunta 19

Pregunta
Specify the correct meaning of the terms:
Respuesta
  • Livores - postmortem discoloration
  • Algor mortis - Stiffness of muscles
  • Rigor morits - cooling of the body
  • Decay of body - Autolytic changes

Pregunta 20

Pregunta
Which of the listed cellular injuries are irreversible:
Respuesta
  • Necrosis
  • Apoptosis
  • Fatty degeneration
  • Cellular edema

Pregunta 21

Pregunta
Which of the following deposits are expression of protein degeneration?
Respuesta
  • Caunsilman's bodies
  • Russel's bodies
  • Mallory's bodies
  • Asteroid bodies

Pregunta 22

Pregunta
"Tiger" heart is diagnosed in view of:
Respuesta
  • Subepicardial adipose tissue
  • Papillary muscle
  • Interventricular septum
  • The area of heart attacks of the left ventricle

Pregunta 23

Pregunta
Amyloid has the following characteristics:
Respuesta
  • Shines in polarized light in Tioflavin S
  • In Congorot shows no fluorescence
  • Ultrastructurally has fibrillary structure
  • Shows metachromasia on Perls

Pregunta 24

Pregunta
The reaction with the Prussian blue is used for the detection of:
Respuesta
  • Mealnin
  • Bilirubin
  • Hemosiderin
  • Calcium

Pregunta 25

Pregunta
Hyaline is:
Respuesta
  • Uniform, transparent and colourless
  • Cellular degeneration product
  • Extracellular degeneration deposit
  • Causes an inflammatory response at the site of deposition

Pregunta 26

Pregunta
Metachromasia is:
Respuesta
  • Immunohistochemical reaction
  • Expression of cellular atypia
  • Changes the primary colour of the stain depending on the chemical composition of the substance
  • Impregnative methodology for argyropfilic fibers

Pregunta 27

Pregunta
Which colours are used in the detection of amyloid?
Respuesta
  • Sudan 3
  • Congorot
  • Iodine + Sulfuric Acid (H2So4)
  • Thiophlavin S - UV

Pregunta 28

Pregunta
Which of the listed terms are related to amyloid deposit?
Respuesta
  • Porfiric down
  • Sago Spleen
  • Big White Kidney
  • Flint Liver

Pregunta 29

Pregunta
Point the main histological types of necrosis:
Respuesta
  • Coagulative necrosis
  • a heart attack
  • Gangrene
  • Liquefactive necrosis

Pregunta 30

Pregunta
Mutilation means:
Respuesta
  • A form of biological mutation
  • Pendulum-like movement of the blood
  • Zonal hair loss
  • Selfamputacion of the phalanges

Pregunta 31

Pregunta
A complete resection of altered tissue is achieved with:
Respuesta
  • Incisive biopsy
  • Excisive biopsy
  • Aspiration biopsy
  • Puncture Biopsy

Pregunta 32

Pregunta
Specify the characteristic signs of mucoid edema
Respuesta
  • Positive staining for fibrin
  • The basic substance shows eosinophillia
  • Positive PAS reaction
  • the transverse strip of collagen

Pregunta 33

Pregunta
Hyaline-drop degeneration is:
Respuesta
  • Extracellular
  • Cellular
  • Protein
  • CARB

Pregunta 34

Pregunta
Indicate pathological processes and diseases in which develops widespread connective tissue hyalinosis
Respuesta
  • Rheumatoid arthritis
  • Rheumatism
  • In hypertensive disease
  • Atherosclerosis

Pregunta 35

Pregunta
Whats true?
Respuesta
  • Android obesity can be seen in women
  • Gynoid obesity is of superior type
  • Dercum's disease is due to pluriglandular endocrinopathy
  • In Madelunga syndrome

Pregunta 36

Pregunta
Specify which pigments are related to hemoglobinogenic:
Respuesta
  • Hemosiderin
  • Melanin
  • Lipofuscin
  • Porphyrin

Pregunta 37

Pregunta
Which pigments are formed in the center of hematomas
Respuesta
  • Hemosiderin
  • Lipofuscin
  • Hemomelanin
  • Hematoidin

Pregunta 38

Pregunta
The mechanical jaundice is:
Respuesta
  • Holostatic
  • Posthepatic
  • Direct
  • Hemolytic

Pregunta 39

Pregunta
In mechanical jaundice
Respuesta
  • Indirect bilirubin in the blood revails
  • In urine urobilinogen is not found
  • In the urine is found bilirubin
  • Stools are hyperpigmented

Pregunta 40

Pregunta
The reactions for the Purssian blue is used for:
Respuesta
  • Tattoos
  • Proof of bilirubin
  • Proof of hemosiderin
  • in hemochromatosis

Pregunta 41

Pregunta
In hemolytic jaundice is found:
Respuesta
  • Indirect bilirubin in the blood prevails
  • In urine urobilinogen is found
  • In the urine is found bilirubin
  • Stools are hyperpigmented

Pregunta 42

Pregunta
Specify which pigments are deposited in Brown atrophy of the liver?
Respuesta
  • Melanin
  • Lipofuscin
  • Hemosiderin
  • Hematoidin

Pregunta 43

Pregunta
Specify the characteristic signs of hemosiderin
Respuesta
  • Does not contain iron
  • Contains iron
  • Located in living cells
  • Is found extracellularly

Pregunta 44

Pregunta
Specify which pigments are elevated in hemolytic jaundice
Respuesta
  • Ferritin
  • Hemosiderin
  • Direct bilirubin
  • Indirect bilirubin

Pregunta 45

Pregunta
Specify the conditions and diseases in which is seen distrophic/degenerative/calcification
Respuesta
  • Aterocalcinosis
  • Deposition of calcium in the vessels of the stomach
  • Phlebolites
  • Calcifications in Primary Tuberculous Complex

Pregunta 46

Pregunta
Hyaline is deposited
Respuesta
  • In plasma incorporation into vessel wall
  • End of local inflammatory processes
  • Outcome of fibrinoid necrosis
  • Liquefactive Necrosis

Pregunta 47

Pregunta
Where is developing fatty degeneration of liver in hyperlipidemia by overconsumption:
Respuesta
  • At the periphery of lobules
  • Diffuse
  • In the Centre of lobules
  • Is not developing a fatty degeneration

Pregunta 48

Pregunta
Specify which pathological processes show calcium metastases:
Respuesta
  • Hypercalcemia
  • Necrosis
  • Hypervitaminosis A
  • Atherosclerosis

Pregunta 49

Pregunta
Specify the conditions in which there is hyperpigmentation of the skin
Respuesta
  • Addison's disease
  • Ephelides
  • Vitiligo
  • Nevus

Pregunta 50

Pregunta
Which of the listed terms are associated with Amyloidosis?
Respuesta
  • Porphiric Spleen
  • Sago spleen
  • Large white kidney
  • Flint Liver

Pregunta 51

Pregunta
Specify the characteristic macroscopic change of organs in Amyloidosis
Respuesta
  • Glazed spleen
  • Arteriolosclerotic Nephrosclerosis
  • Lardaceous ham spleen
  • Large White Kidney

Pregunta 52

Pregunta
For amyloidosis is not characteristic one of the following qualitie
Respuesta
  • Metachromasia
  • Positive staining with Sudan 3
  • Wax Density
  • Translucent

Pregunta 53

Pregunta
Point two possible outcomes of hydropic degeneration
Respuesta
  • Recovery
  • Transition in CARB degeneration
  • Intracelluar deposits of calcium salts
  • Necrosis

Pregunta 54

Pregunta
Which of the listed cellular injuries are irreversible
Respuesta
  • Necrosis
  • Apoptosis
  • Balloon degeneration
  • Necrobiosis

Pregunta 55

Pregunta
Hemolytic jaundice may be:
Respuesta
  • Subhepatic
  • Prehepatic
  • Indirect
  • Obstructive

Pregunta 56

Pregunta
Which of the following is not a form of Amyloidosis
Respuesta
  • Primary
  • Reactive
  • Parenchymal
  • Local

Pregunta 57

Pregunta
In which diseases often develop Amyloidosis
Respuesta
  • Bronchiectatic disease
  • Malignant myeloma
  • Arterial hypertension
  • Rheumatoid artritis

Pregunta 58

Pregunta
Bilateral eyelid skin of adult shows nodules with yellow colour and rice grains, they are:
Respuesta
  • Xanthelasmi
  • Nevus pigmentosus
  • Ephelides
  • Hemosiderin deposits

Pregunta 59

Pregunta
In which diseases calcium deposits are called dystrophic?
Respuesta
  • At athercalcinosis
  • In the arterioles of the kidney
  • Psammoma type of meningeoma
  • In the heart valve defect

Pregunta 60

Pregunta
The comparison "signet ring cell" with a stone facing inwards is used in:
Respuesta
  • In fatty degeneration of hepatocytes
  • Mucus-producing adenocarcinoma
  • Vacuolar degeneration of hepatocytes
  • Henle's loop epithelial cells degeneration

Pregunta 61

Pregunta
Specify the typical deposition of amyloid for primary amyloidosis:
Respuesta
  • Pericollagenic
  • Perireticular
  • Pericollagenic and Perireticular
  • Intracellular

Pregunta 62

Pregunta
In the stomach is found a large tumor with mucus collection. Microscopically in the tumor slides are detected tumor cells with a doughnut shape which cytoplasm show PAS-positive stain. What type of degeneration is depicted in this case?
Respuesta
  • Mucus degeneration
  • Fatty degeneration
  • Hyaline-drop degeneration
  • Fibrinoid degeneration

Pregunta 63

Pregunta
Indicate which of the following conditions is an example of local hemosiderosis:
Respuesta
  • Hemolytic anemia
  • Brown lung induration
  • Brown atrophy of liver
  • Lipogranulom

Pregunta 64

Pregunta
Specify enzymes involved in melanogenesis
Respuesta
  • Hyaluronidase
  • Tirozinaza
  • DOPA-oxidase
  • Lipase

Pregunta 65

Pregunta
The sequence of local structural changes in the course of the disease is called
Respuesta
  • Sanogenesis
  • Pathogenesis
  • Tanathogenesis
  • Morphogenesis

Pregunta 66

Pregunta
The mechanical jaundice is:
Respuesta
  • Indirect
  • Posthepatic
  • Direct
  • Hemolytic

Pregunta 67

Pregunta
Hyaline is deposited in
Respuesta
  • In plasma insudation
  • Liquefactive necrosis
  • As outcome of fibrinoid necrosis
  • As outcome of local inflammatory processes

Pregunta 68

Pregunta
Specify the conditions under which does not develop fatty degeneration of the liver:
Respuesta
  • Active hyperemia
  • Chronic pulmonary heart
  • Anemia
  • Diabetes mellitus

Pregunta 69

Pregunta
Which of the following is not a form of amyloidosis
Respuesta
  • Primary
  • Reactive
  • Into paraenchymal cells
  • Local
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