CD4 (T-Helper) Cell Polarisation

Descripción

Year 2 Test sobre CD4 (T-Helper) Cell Polarisation, creado por gina_evans0312 el 16/04/2014.
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Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312 hace más de 10 años
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Resumen del Recurso

Pregunta 1

Pregunta
Th cells are activated by MHCII and a co-stimulation signal
Respuesta
  • True
  • False

Pregunta 2

Pregunta
CD4 T-cells are a major source of cytokines after activation
Respuesta
  • True
  • False

Pregunta 3

Pregunta
Which of the following is a major autokrine stimulator for clonal proliferation of Th cells?
Respuesta
  • IL2
  • IL3
  • IL4

Pregunta 4

Pregunta
Which of the following is not a factor in CD4 cell polarisation?
Respuesta
  • Infection type (I.e. does the microenvironment indicate a fungus, a virus?)
  • Amount of antigen/binding strength of antigen
  • 'Dose' of infection

Pregunta 5

Pregunta
Production of cytokines by one type of Th cell, causes the polaristion of native Th cells to the type that produced the cytokines (i.e. Th1 produced cytokines encourage Th1 conversion)
Respuesta
  • True
  • False

Pregunta 6

Pregunta
During non-infection, which cell is predominant?
Respuesta
  • Th1
  • Th2
  • Neither, till infection tips the balance

Pregunta 7

Pregunta
Name ways in which the activity of cytokines can be controlled
Respuesta
  • Short half life- only effect nearby cells
  • Specific receptors prevent unwanted signalling
  • High concentrations needed for cell activation
  • Active destruction by incorrect cells
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