Cancer & Autoimmune Disease: Quiz the Sixth

Most cancers could be prevented.

Which 3 of the following abberations cause a proto-oncogene to mutate into an oncogene?

BCR-ABL is an oncogene caused by the translocation of two genes on chromosome 9 and 22. The new chromosome that this forms is called the _______ chromosome

Select some of the functions of a tumour-suppressor gene's encoded protein.

Caretaker genes are a class of tumour suppressor genes however, they do not regulate cell division. Instead they...

Bystander or passenger mutations are mutated genes that are not related to the growth or development of a cancer.

Differentiation, increasingly autonomous growth and aggressive behaviour are trates associated with a cancer in ______ stage of carcinogenesis

Some pathogens are capable of establishing chronic infections at certain sites in the body. This creates a local environment where even uninfected cells are at a greater risk of becoming cancerous.

There are four types of genetic disorder. Which of the following best describes each of these four types

Down's syndrome frequency increases with paternal age.

Tumour antigens may be specific to a tumour (TSA), or just occur more frequently in a tumour (TAA). Both must be capable of inducing an antibody or cell-medicated response.

An immune response against self antigen(s) that results in a disease causing tissue damage or disturbed physiological function best describes...