L21 Bioelectricity: Membrane Potentials in Neurons

Descripción

Know the two main cations that contribute to the electrical properties of a neuron. Understand the different ways these cations can move across the semi-permeable membrane of the neuron (channels vs pump). List the different types of polarisation of a nerve cell membrane. Explain what is meant by the resting membrane potential. Explain what is meant by a local potential.
Mer Scott
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Mer Scott
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Resumen del Recurso

Pregunta 1

Pregunta
The phospholipid bilayer is an insulator which cations cannot pass through, but anions can.
Respuesta
  • True
  • False

Pregunta 2

Pregunta
Choose the incorrect statement about ions and the RMP.
Respuesta
  • At RMP, concentration of Na+ is low inside the cell.
  • Normal ECF concentration of Na+ is 135-145mmol/L
  • At RMP, K+ concentration is high outside of the cell.
  • Normal ECF concentration of K+ 3.5-5mmol/L

Pregunta 3

Pregunta
The Na+/K+-ATPase pumps 3 Na+ out of the cell against their gradient and 2 K+ ions into the cell against their gradient.
Respuesta
  • True
  • False

Pregunta 4

Pregunta
Cells are at RMP the majority of the time.
Respuesta
  • True
  • False

Pregunta 5

Pregunta
Choose the incorrect statement.
Respuesta
  • At RMP, most Na+ channels are closed
  • At RMP, some K+ channels are closed
  • Na+/K+-ATPase is inactive

Pregunta 6

Pregunta
At RMP if more Na+ channels open, the cell becomes depolarised meaning it becomes more negative (-) in comparison to the ECF
Respuesta
  • True
  • False

Pregunta 7

Pregunta
Choose the correct statements.
Respuesta
  • At RMP K+ outflow is slightly larger than Na+ inflow
  • Na+ channels opening causes depolarisation up to +30mV
  • K+ channels opening causes repolarisation
  • Hyperpolarisation is due to Na+ channels closing before K+ gradient is fully established

Pregunta 8

Pregunta
Depolarisation is inhibitory, hyperpolarisation is excitatory.
Respuesta
  • True
  • False
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