Biology 4.1.1 Cells in the immune system

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A level (4.1.1 Diseases) Biology Fichas sobre Biology 4.1.1 Cells in the immune system, creado por Sam Gunnell el 02/06/2019.
Sam Gunnell
Fichas por Sam Gunnell, actualizado hace más de 1 año
Sam Gunnell
Creado por Sam Gunnell hace alrededor de 5 años
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How does the immune system detect pathogens? Antigens on the surface of the pathogens are detected as foreign which activates an immune response
What are the two types of cells in the immune system? Phagocytes Lymphocytes
What do phagocytes do? Remove dead/invading cells
What are the two types of phagocytes? Neutrophils Macrophages
What do neutrophils do? Travel around in capillaries and can squeeze out of capillaries at any time to find and engulf pathogens
What do macrophages do? They travel to an organ and stay there and fight pathogens if they turn up
Where are phagocytes and lymphocytes produced? Bone marrow
What do opsonins do? They bind to pathogens and "tag" them so that they can easily be identified by phagocytes and can also act as a binding site for phagocytes
What do lymphocytes do? Involved in producing antibodies
What are the two types of lymphocytes? T lymphocytes B lymphocytes
What do T lymphocytes do? They have receptors on their surface that are specific to an antigen but only if it is presented with a self-protein (antigen presenting macrophage)
What happens when the T lymphocyte finds a complimentary receptor? The macrophage releases cytokines which activate the T lymphocyte and these active T lymphocytes divide by mitosis forming identical T cells
What are the four types of T lymphocyte cell? -T helper -T killer -T memory -T regulator
What do T helper cells do? Produces cytokines that stimulate the macrophage to ingest the pathogen
What do T killer cells do? They destroy the cells they bind to
What do T memory cells do? Helps the body to respond to the same reoccurring antigen
What do T regulator cells do? Stops the immune system once the pathogen is destroyed so that autoimmune diseases don't develop
What do B lymphocytes do? They have cell embedded antibodies which act as receptors for antigens and they can become antigen presenting cells
What happens when a b lymphocyte finds a complimentary antigen? The b lymphocyte becomes activated (the t helper cells help activate more). The activated cells divide many times by mitosis ad then differentiate into plasma cells
What is a plasma cell? Larger cells with more organelles that synthesise particular antibodies
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