BMS10-1022 - Introduction to the CVS and Physics of Blood Flow

Descripción

distinguish between flow and velocity i Define cardiac output, systole/ diastole the value of the normal cardiac output relationship between MAP, COt & peripheral resistance, + why arterioles are main contributors to latter. role and limitations of passive diffusion for substance movement Understand factors influenc flow through tubes, eg. pressure, vessel calibre, resistance to flow and viscosity, and why blood vessels arent rigid laminar/turbulent flow+factors
Evian Chai
Fichas por Evian Chai, actualizado hace más de 1 año
Evian Chai
Creado por Evian Chai hace más de 4 años
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Resumen del Recurso

Pregunta Respuesta
During ventricular systole, which valves are open? Pulmonary and aortic valves
During ventricular diastole, which valves are open? Tricuspid/Mitral
What are the two determinants of Blood Pressure? 1. Gravity (higher BP in lower body) 2. Aorta/large arteries (level of vasoconstriction determines TPR)
The pulmonary circulation comes from the ... ventricle. It is ...pressure/resistance Right Low
The systematic circulation comes from the ... ventricle. It is ...pressure/resistance Left High
What is the purpose of the portal system? Nutrients are delivered to the liver for detox/processing
What is the difference between laminar and turbulent flow? At what point is it considered turbulent flow? Laminar flow happens with axial streaming and is lower resistance, while turbulent flow is higher resistance and bumpy. When Reynold's number >4000
What four factors increase resistance/murmurs and cause turbulent flow? 1. Increase in diameter without decrease in velocity 2. High velocity 3. Sharp edges 4. Branching
How do the flexibility of the tubes help regulate flow? 1. Tubes can expand in diameter (dilate) to accommodate flow 2. Myogenic Tone means muscle can constrict to prevent overly-high flow
What is flow like in the capillaries? Happens one RBC at a time
Cardiac output is a measure of what? The two equations are... Volume of blood ejected per minute SV*HR or MAP/TPR
What does ejection fraction measure? Ejection fraction is calculated by? What does a ejection fraction of less than 40% indicate? How much of the blood in the left ventricle is pumped out Stroke Volume/End Diastolic Volume Heart failure
Flow in the heart is measured by .../min and is equal to... Liters/min Equal to cardiac output
What is the difference between stroke volume and cardiac output? Stroke volume is the volume per beat, while cardiac output is the volume per minute
How is flow out of the heart (SV/CO) calculated with end diastolic/end-systolic volume? End diastolic-end systolic volume
What are the two equations for Mean Arterial Pressure? 1. Diastolic pressure + ((systolic-diastolic)/3) 2. CO*TPR
What is the afterload? The Total Peripheral Resistance as determined by smooth muscle contraction in the artery
According to Darcy's Law, what is the equation for flow? (P1-P2)/Resistance
What is the equation for Resistance (R) R= (8*viscosity*length of tube)/pir^4 =(8VL)/pir^4
How is resistance totalled in blood vessels in series? Rs added together
How is resistance totalled in blood vessels in parallel? (eg. capillaries) 1/R1+1/R2....
What is normal CO in a healthy adult? 5 L/min
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