3228744
| Pregunta | Respuesta |
| Leuprolide | GnRH analog גורם לשחרור מתמשך של GnRH בשימוש להורדת רמות טסטוסטרון וDHT "start up flare" |
| Finasteride | 5- Alpha reductase inhibitore Treatment of BPH הורדת רמות DHT בלבד |
| Liraglunide | GLP-1 receptor agonist Gs mediated Insulin secretion |
| Exenatide | GLP-1 receptor agonist Gs mediated Insulin secretion |
| Aromatase inhibitors | Anastrozole, Letrozole, Exemestane For treatment of breast cancer |
| NO containing Bisphosphonate | Aledronate, Risedronate, Zoledronic acid |
| Aledronate mecchanisem | FPP synthease inhibitor- osteoclast bone resorption inhibitors |
| Teriparotide | PTH analoge |
| Denosumab | Anti RANKL- Pre-osteoclast maturation inhibitor |
| Pioglitazone Rosiglitazone | Thiazolidinedions |
| Thiazolidinedions- Mechanisem | Binds to PPAR-gamma nuclear transtription regulatore. מורידים התנגדות לאינסולין בעיקר בעזרת העלאת adiponectin |
| Thiazolidinedions- side effects | Weight gain, edema, hepatotoxicity, HF, incrise risk of fructures |
| Acrbose Miglitol | Alpha- glucosidase inhibitors |
| Bromocriptine Cabergoline | Dopamine agonist |
| Pegvisomant | GH hormone receptor antagonist |
| Tesamorelin | GHRH analog- used to treat HIV- associated lopodystrophy |
| Aspart, Glulisine, lispro | Insulin- short acting |
| Detemir, Glargin | Insulin- long acting |
| Chlorpropamide Tolbutamide | First generation Sulonylureas |
| Glimepiride Glipizide Glyburide | Second generation Sulonylureas |
| Sitagliptin Saxagliptin Linagliptin | DDP-4 inhibitors 2 DM |
| Pramlintide | Amylin analog- reduce gastic emptying and glucagone secretion |
| Canagliflozin | SGLT-2 inhibitor Block reabsorbtion of glucose in PCT |
| Conivaptan Tolvaptan | ADH antagonist- SIADH, block action of ADH at V2 recetpors |
| Desmopressin acetate | Central diabetis insipidos |
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