Creado por Delicia Moodley
hace alrededor de 9 años
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Pregunta | Respuesta |
Hypernatraemia | Symptoms: Hypertension Dyspnoea Convulsions Oedema |
Hyponatraemia | Symptoms: Hypotension Tachycardia Lethargy Muscle Weakness |
Hypokalaemia | Symptoms: Muscle weakness Abnormal ECG Paralytic ileus |
Hyperkalaemia | Symptoms: Weakness Cardiac arrhythmia/arrest Parasthesia |
Respiratory acidosis | Causes: Hypoventilation Airway obstruction Sedative overdose Faintness Coma |
Respiratory alkalosis | Causes: Hyperventilation Anxiety/ Fever Heart failure Faintness Headache |
Metabolic acidosis | Causes: Renal failure Diarrhoea Diabetes High protein intake Lactic acid production |
Metabolic alkalosis | Causes: Vomiting of H+ IV infusion of HCO3 K+ deficiency Intake of alkaline substances |
Anion Gap Metabolic Acidosis | Causes: Lactic acidosis Keto-acidosis Renal failure Poisoning: ethanol |
Acute Renal Failure | Rapid loss of renal function Retain: urea, creatinine, H+ ions, metabolic waste Oliguria |
Acute Kidney Injury | Causes: Pre-renal: Hypovolaemia, Decreased cardiac output Intra-renal: Tubular necrosis, glomerulonephritis, tubular obstruction, intrarenal vasoconstriction Post-renal: urethral obstruction |
Chronic Renal Failure | Causes: Structural damage to kidney Glomerulonephritis Hypertension Diabetes Mellitus Renovascular disease |
Nephrotic Syndrome | Symptoms: Proteinuria, hypoproteinaemia, hypercholesterolaemia, oedema Causes: Glomerulonephritis, cancer, drugs, infection, SLE |
Renal Tubular Acidosis | Symptoms: High urine pH, Normal/slightly decreased glomerular function, Normal AG metabolic acidosis Types: 1: [DCT] H+ not excreted 2: [PCT] defective HCO3- reabsorption |
Renal Calculi | Causes: Dehydration Alkaline urine Hypercalcuria Hyperoxaluria |
Hyperbilirubinaemia | Causes: Prehepatic- Haemolysis Hepatic- Acute viral or toxic hepatitis Post-hepatic- Gallstones, cholecystitis, tumours |
Addison's disease | Causes: Glucocorticoid treatment, autoimmune adrenalitis, TB, adrenal haemorrhage Symptoms: Tiredness, weakness, N & V, weight loss, hypotension, loss of body hair |
Cushing's syndrome | Causes: Corticosteroid or ACTH treatment, pituitary hypersecretion of ACTH [Cushing's disease], Adrenal adenoma/carcinoma Symptoms: Upper body obesity (thin arms/legs), buffalo hump, hypertension. hyperglycaemia |
Conn's Syndrome | Causes: Adrenal adenoma/carcinoma, hypertrophy Symptoms: hypertension, muscle weakness, tetany, paraesthesia, polydipsia. polyuria |
Hyperthyroidism [Thyrotoxicosis] | Clinical signs: Increased appetite, diarrhoea, increased adrenergic activity (tachycardia), heat intolerance, exophthalmos, goitre Biochem. signs: High T4 & T3, low TSH, increased metabolism, hypocholesterolaemia Causes: Grave's disease, goitre, thyroiditis, Iodine drugs, tumours |
Grave's disease | Genetic, autoimmune disease. Antibodies bind to TSH receptors and mimic effects of TSH. Results in Goitre & exophthalmos |
Hypothyroidism [myxoedema] | Clinical signs: Lethargy, tiredness, facial puffiness, cold intolerance, weight gain, bradycardia, slow reflexes Biochem. signs: Low T4 & T3, high TSH, hypercholesterolaemia Causes: Hashimoto's, Iodine deficiency, cretinism (kids) |
Hashimoto's thyroiditis | Autoimmune disease where antithyroid antibodies destroy thyroid |
Hypercalcaemia | Caused by: Common: Malignancy, Primary hyperparathyroidism Less common: Thyrotoxicosis, sarcoidosis, Tertiary HPT Symptoms: Bones, stones, abdominal groans, psychic moans |
Hypocalcaemia | Caused by: Low PTH- HypoPT, Hypomagnesaemia Vitamin D deficiency, acute pancreatitis. EDTA contamination [sample] Symptoms: Numbness, tetany [facial muscle twitch], convulsions |
Hyperphosphataemia | Inhibits a-1 hydroxylation of vit. D Causes: Renal impairment, hypocalcaemia, hypo PT, acromegaly |
Hypophosphataemia | Caused by: Resp alkalosis, N & V, malabsorption, RTA, primary HPT, |
Hypermagnesemia | Uncommon Caused by: RF Bronchospasm [asthma] |
Hypomagnesaemia | Caused by: Malnutrition, alcoholism, diuretics, cirrhosis Symptoms: Tetany, ataxia, muscle weakness, Agitation |
Ricketts [children] & Osteomalacia [adults] | Caused by: Calcium deficiency due to problems with vit. D [reduced absorption/production or insensisitivity] |
Osteoporosis | Reduction in bone mineral density [bone = fracture prone] caused by increased osteoclast activity Primary: Decreased oestrogen Secondary: DM, thyrotoxicosis, alcoholism |
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