Creado por gina_evans0312
hace casi 11 años
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Pregunta | Respuesta |
Basis of Catcholamines | Tyrosine- made into a catechol ring & a modifiable amide base |
Noradrenaline- Location | Central nervous system and sympathetic nervous system |
Noradrenaline- Action | Generally inhibitory |
Noradrenaline- Method of work | Hyperpolarisation |
Noradrenaline- Excess | Mania |
Noradrenaline- Deficiency | Depression |
Dopamine- Location | A central nervous system |
Dopamine- Action | Primarily inhibitory |
Dopamine- Excess | Schitzophrenia/Psychosis |
Dopamine- Deficiency | Parkinsons |
Adrenaline- Production | Chromaffin cells in adrenal medulla |
Adrenaline- Location | CNS |
Adrenaline- Action | Fight or flight response |
Hypertension- Catcheolamines | Increased CA's increase vascular tone and blood pressure |
CA Production- Tyrosine | Basis of all CA's |
CA Production- DOPA | Created from tyrosine using Tyrosine Hydroxylase |
CA Production- Dopamine | Produced from DOPA using DOPA decarboxylase |
CA Production- Noradrenaline | Created from Dopamine using Dopamine-Beta-Hydroxylase (found in vesicles, where it's stored) |
Adrenaline | Created from Noradrenaline using Phenylethanolamine & S-Adenosyl Methionine, and is stored in vesicles |
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