E.Coli

Pregunta	Respuesta
Diarrhea	Change in frequency/consistency of stools
Dysentry	Abdominal pain, stool with blood/mucus
E.Coli- Gram Staining	Gram -ve bacilli
Coliform	Bacteria used to indicate sanitary conditions of food/water
E.Coli- Movement	Has peritrichous flagella
E.Coli- Lactose Fermenation	Positive
E.Coli- Culture Media	Grow on McConkey Agar
E.Coli- Antigens (Somatic)	Somatic O- Not species specific & causes many cross reactions
E.Coli- Antigens (Flagellar)	Flagellar H (Species specific, fewer cross reactions
E.Coli- Strain Recognition	Done through strains H & O combination
Serotype	A serologically distinguishable strain, leading to a specific disease syndrome
E.Coli- Common Infections	Urinary Tract Infections, Diarrhea
Pathotype	Infraspecific pathogen classification based on its pathogenicity in specific hosts
E.Coli- ETEC	Enterotoxic E.Coli
E.Coli- ETEC (CFAs)	Colonisation Factor Antigens that allow bacteria to bind to intestinal epithelial cells
E.Coli- ETEC (ST)	Stable Toxin- released to stimulate cGMP production
E.Coli- ETEC (LT)	Labile Toxin- Released to increase cAMP production
E.Coli- ETEC (Effect of ST & LT)	Increase lumen electrolytes, leading to diarrhea
E.Coli- ETEC (Infections)	Travelers diarrhea, varies from mild to severe
E.Coli- EPEC-	Enteropathogenic E.Coli
E.Coli- EPEC (Initial Attachment)	Uses bundle forming pili
E.Coli- EPEC (Intimate Attachment)	Done through a Type 3 Secretory System
E.Coli- EPEC (LEE)	Locus Enteric Effacement- pathogenicity island containing a needle like structure that injects host cell wall with Tir protein
E.Coli- EPEC (Tir Protein)	Remains in host cell wall and allows E.Coli to bind using Intimin on bacterial cell wall
E.Coli- EPEC (Effect on Cell)	Binding creates lesions that destroy the microvilli
E.Coli- EPEC (Infections)	Diarrhea in children under 2
E. Coli- EHEC/STEC/VTEC	3 Names, 1 Strain of E.Coli
E.Coli- EHEC	Enterohaemorrhagic E.Coli (due to bloody diarrhea)
E.Coli- STEC	Shiga Toxin Producing E. Coli- this strain produces Shiga toxin
E.Coli- VTEC	Veryocytoxin Producing E.Coli
E.Coli- EHEC/STEC/VTEC (Infections)	Haemorrhagic colitis (blood in feces) and is linked to Serious Haemolytic Uremic Syndrome
E.Coli- EHEC/STEC/VTEC (Reservoir)	Cattle
E.Coli- EHEC/STEC/VTEC (Sources)	Contaminated meat/vegetables
E.Coli- EHEC/STEC/VTEC (Binding)	Binds through pathogenicity islands like EPEC strain
E.Coli- EHEC/STEC/VTEC (Stx Phage)	Encodes the Shiga toxin
E.Coli- EHEC/STEC/VTEC (Shiga Secretion)	Can't happen- no secretory system- so toxin is released by cell lysis (hence no antibiotics on infection)
E.Coli- EHEC/STEC/VTEC (Receptor GB3)	Target of Shiga toxin on Pantch cells (intestine) or kidney epithelial cells
E.Coli- EHEC/STEC/VTEC (Effect of Shiga Toxin)	Prevents protein synthesis- leading to RBC lysis and kidney damage

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	Creado por gina_evans0312 hace casi 11 años