Glucose-6-Phosphate Dehydrogenase

Descripción

(Inborn Errors of Metabolism) Year 2 Fichas sobre Glucose-6-Phosphate Dehydrogenase, creado por gina_evans0312 el 05/04/2014.
gina_evans0312
Fichas por gina_evans0312, actualizado hace más de 1 año
gina_evans0312
Creado por gina_evans0312 hace más de 10 años
224
0

Resumen del Recurso

Pregunta Respuesta
Drug Induced In susceptable individuals
Symptom Haemolytic Anaemia
G-6-PDH is part of... Pentose Phosphate pathway
Reaction Glucose-6-P + NADP --> NADPH + P-Gluconolactine
Role of Pathway To reduce glutathiones, which keep Hb and RBC membrane proteins in their reduced form
Peroxides Reduces peroxides
Effect of Antimalarials Contain peroxides which cannot be reduced, Hb becomes oxidised to Methemoglobin, and the spleen destroys the RBCs
Favism Mediterranean form of deficiency- occurs when Fava beans are eaten
Fava Beans Also contain peroxides, same effects
Protection May confer protection from Fulciparum malaria, which rely on glutathiones at one point
Mostrar resumen completo Ocultar resumen completo

Similar

Von Gierkes Disease
gina_evans0312
Galactosaemia
gina_evans0312
Congenital Phorphyria
gina_evans0312
Head, Neck and Back 2nd Sem- Anatomy 2nd Year- PMU
Med Student
Respiratory System 2nd Year PMU Anatomy
Med Student
Respiratory System Year 2/
Sole C
Fiction or NonFiction Year 1
Judy Stephenson
Fiction or NonFiction Year 2
Judy Stephenson
Anatomy Year 2 - Head, Neck and Back
Sole C
Lipid Structure
gina_evans0312