Celiac disease

Descripción

Mapa Mental sobre Celiac disease, creado por fatima alkhateeb el 10/02/2018.
fatima alkhateeb
Mapa Mental por fatima alkhateeb, actualizado hace más de 1 año
fatima alkhateeb
Creado por fatima alkhateeb hace casi 7 años
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Resumen del Recurso

Celiac disease
  1. Anatomy
    1. Duodenum
      1. Jejunum
        1. Ileum
        2. Definition
          1. Immune mediated damage of small bowel villi due to gluten exposure
          2. Causes
            1. Inappropriate T cell and IgA mediated response against gluten in genetically predisposed persons
              1. Gliadin is deaminated which is then grabbed by APC’s and are presented via MHC II to Th cells which mediate tissue damage
            2. Signs and symptoms
              1. Steatorrhea
                1. Weight loss
                  1. Failure to thrive
                    1. Vitamin deficiency
                    2. Pallor (anemia)
                  2. Investigations
                    1. Endoscopy
                      1. Genetic testing
                        1. Histology
                        2. Pathology
                          1. Management
                            1. Gluten-free diet
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