Autonomic nervous system overview

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Autonomic nervous system overview
  1. Sympathetic: The "Fight or Flight" response
    1. Increased HR and BP
      1. Pupil dilation
        1. Inhibits salivation
          1. Dilates bronchioles
            1. Inhibits digestion
              1. Increased glucose
                1. Peripheral vasoconstriction
                  1. Relaxed bladder
                    1. Ejaculation and orgasm
                2. Norepinephrine
                  1. Group called catecholamines
                    1. Target organ receptors called adrenergic receptors
                      1. Alpha and beta receptors (pg 147)
                      2. Broken down by monoamine oxidase
                      3. Epinephrine
                        1. Adrenal gland most responsible for release
                          1. Activates alpha and beta receptors, but has an affinity for beta
                            1. Terminated through hepatic metabolism
                          2. Prasympathetic: The "Rest and Digest" response
                            1. Constricts pupils
                              1. Stimulates salivation
                                1. Slows heart rate, decreases contractility
                                  1. Constricts bronchioles
                                    1. Stimulates digestion
                                      1. Stimulates gallbladder function
                                        1. Contracts bladder
                                          1. Stimulates erection and lubrication
                                            1. Decreased HR and BP
                              2. Acetylcholne
                                1. Cholinergic nerves RELEASE Ach. Their receptors are:
                                  1. Nicotinic- Located at the ganglionic synapse in parasympathetic and sympathetic NS
                                    1. Located in a lot of places, including skeletal muscle
                                      1. Activation causes tachycardia, hypertension, and increased tone and motility in digestive tract
                                        1. Very little clinical use
                                        2. Muscarinic- Located on target tissues affected by postganglionic neurons in parasympathetic NS
                                        3. Broken down by acetylcholinesterase (AchE
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