Specific Immune Response

Descripción

According to OCR Biology Specification (used for summer 2015)
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Resumen del Recurso

Specific Immune Response
  1. Pathogen engulfed and partially digested by macrophages
    1. Macrophage becomes antigen-presenting cell
      1. Clonal selection to find correct T lymphocytes
        1. Clonal expansion to reproduce T helper cells through mitosis
          1. Release of cytokines (interleukins) to stimulate proliferation
            1. Activation of B cells
              1. Clonal expansion to reproduce B cells
                1. Some differentiate to make plasma cells
                  1. Plasma cells manufacture antibodies
                  2. Some differentiate to make B memory cells
                    1. Memory cells circulate in body to provide immunological memory
            2. B cells mature in bone marrow
              1. T cells originate in bone marrow but mature in thymus gland
                1. Clonal expansion to reproduce T killer cells
                  1. T killer cells search for infected cells
                    1. T killer cells attach to infected cells
                      1. T killer cells secrete toxic substances (hydrogen peroxide) into infected cells to kill cells and pathogens inside it
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