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Specific Immune Response
- Pathogen engulfed and partially digested by macrophages
- Macrophage becomes antigen-presenting cell
- Clonal selection to find correct T lymphocytes
- Clonal expansion to reproduce
T helper cells through mitosis
- Release of cytokines (interleukins) to
stimulate proliferation
- Activation of B cells
- Clonal expansion to reproduce B cells
- Some differentiate to
make plasma cells
- Plasma cells
manufacture antibodies
- Plasma cells
manufacture antibodies
- Some differentiate to
make B memory cells
- Memory cells circulate in
body to provide
immunological memory
- Memory cells circulate in
body to provide
immunological memory
- Some differentiate to
make plasma cells
- Clonal expansion to reproduce B cells
- Activation of B cells
- Release of cytokines (interleukins) to
stimulate proliferation
- B cells mature in bone marrow
- T cells originate in bone marrow
but mature in thymus gland
- Clonal expansion to
reproduce T killer cells
- T killer cells search
for infected cells
- T killer cells attach to infected cells
- T killer cells secrete toxic
substances (hydrogen peroxide)
into infected cells to kill cells
and pathogens inside it
- T killer cells secrete toxic
substances (hydrogen peroxide)
into infected cells to kill cells
and pathogens inside it
- T killer cells attach to infected cells
- T killer cells search
for infected cells
- Clonal expansion to reproduce
T helper cells through mitosis
- Clonal selection to find correct T lymphocytes
- Macrophage becomes antigen-presenting cell
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