296688
Active sites
- determine how the substrate will bind to an enzyme
- R groups of amino acids stick out and create binding specificity for substrates
- non-protein helpers
- cofactors
- inorganic
- inorganic
- coemzymes
- organic
- organic
- cofactors
- inhibitors
- inhibit an enzyme's activity
- competitive
- bind active site of enzyme blocking substrate from entering
- affects km and maybe vmax
- bind active site of enzyme blocking substrate from entering
- noncompetitive
- binds to another part of the enzyme changing its conformation and the substrate can still fit in active site
- effects vmax and maybe km
- binds to another part of the enzyme changing its conformation and the substrate can still fit in active site
- uncompetitive
- bind enzyme once substrate is bound inhibiting product production
- no change to vmax of km
- bind enzyme once substrate is bound inhibiting product production
- allosteric regulation
- changes the shape and therefore the function
- changes the shape and therefore the function
- inhibit an enzyme's activity
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