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Glycogen Phosphorylase Structure (Without Phosphorylation)

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Year 2 Mapa Mental sobre Glycogen Phosphorylase Structure (Without Phosphorylation), creado por gina_evans0312 el 23/10/2013.
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Mapa Mental por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312 hace alrededor de 11 años
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Resumen del Recurso

Glycogen Phosphorylase Structure (Without Phosphorylation)
  1. T Form
    1. Inactive- Active site it buried within protein
      1. Caused by
        1. High ATP
          1. High glucose-6-phosphate
            1. Glucose (In the liver)
        2. R Form
          1. Active- Active site is acessable to glycogen
            1. Caused by
              1. AMP
                1. Pi
                  1. Phosphorylation
              2. Interface domain
                1. Contains allosteric effector site
                  1. Where ATP/AMP binds
                2. Active Site
                  1. Found in deep groove to prevent water entering
                    1. Entrance of water causes hydrolysis instead of phosphorylysis
                      1. Made of
                        1. Glycogen Storage
                          1. Interface
                            1. And C Terminus Domains
                            2. This deep groove is what causes the steric hinderence during cleavage
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