31 pairs of spinal
nerves and all neural
tissue outside of CNS
12 Thoratic nerves
5 Lumbar nerves
1 coccygeal nerve
5 sacral nerves
8 cervical nerves
12 pairs of
cranial
nerves
Afferent division
Sensory info to CNS via
ascending pathway
Efferent division
Motor info to glands
and muscles via
descending pathway
Somatic
nervous system
Skeletal muscle
Autonomic muscle system
Smooth muscle,
Cardiac muscle,
Glands
Sympathetic
Ganglion close to CNS
Parasympathetic
Ganglion close to organ
Cellular organisation in
neural tissues
Neurons
Communication
Large, prominent centrally located
nucleus, lot of mitochondria, lot of
Nissl bodies (RER) for
neurotransmitter production
Axons
Long cell process
Single structure or
branch= collateral axons
Carry impulse
away from body
Dendrites
Short, highly branching
cytoplasmic extenstion
Sensory messengers
to be processed
Cytoskeleton
neurofilament- architecture
Microtubules - axinal transport
Synaptic terminals
Synapse
communication with
other cell
Neuroglia
Support, Defence and
Myelination (insulation)
Oligodendrocytes
Myelination in CNS
Astroglia
White matter - fibrous astrocyte
Grey matter protoplasmic astrocyte
Microglia
Phagocyte in CNS
Ependymal cells
Cubodial or low columnar lining in central
spinal canal, no basement membrane, lining
ventricles in cerebrum rest on basement
membrane and secrete cerebral spinal fluid
Schwann cells
Myelination in PNS
Support non-myellinated axons
which bury themselves into the
schwann cell cytoplasm
Functional classifications
Sensory
Unipolar - single neuron process from cell body
Interneurons
Bipolar neuron - 1 dendrite, 1 axon
Motor
Multipolar- single axon, many dendrites
Spinal reflexes
Stimulus
Receptor
Sensory neuron
Motor neuron
Effectors
Response
No interneuron in
reflex arc of knee jerk
Myelin
Spiral of membrane
wrapped around axon
Increase speed
of conduction
along axon
Space between small units =
nodes of Ranvier
Multiple sclerosis, myelin of CNS attacked by immune system,
destruction results in severe functional deficits, such as
paralysis, loss of sensation and/ or loss of coordination