Beta-Lactamase Inhibitors

Question	Answer
where can you isolate clavulanate potassium	Streptomyces clavuligeris
components of Augmentin under what specific drug does Augmentin belong?	Amoxicillin + Clavulanic acid (K salt) Clavulanate Potassium
it used for the control of serious infections caused by beta-lactamase-producing bacteria	potassium clavulanate + ticarcillin Ticarcillin - extended-spectrum penicillin
it is an penicillanic acid sulfone	Sulbactam
components of Unasyn under what specific drug does Unasyn belong?	ampicillin Na + Sulbactam Na Sulbactam
it is also a penicillanic acid sulfone that is similar to sulbactam	Tazobactam
Piperacillin + Tazobactam	Zosyn injectable
where can you isolate thienamycin	Streptomyces cattleya see p 276
it is a derivative of thienamycin	imipenem
it is an inhibitor of DHP-1 what is DHP-1	Cilastatin dehydropeptidase-1
what are the carbapenems	imipenem - clistatin thienamycin
what are the newer carbapenems	meropenem biapenem
it is a second-gen carbapenem	Meropenem
approved as ________ and is the treatment of infections caused by multiply-resistant bacteria and for empirical therapy for serious infections, such as bacterial meningitis, septicemia, pneumonia, and peritonitis.	Merrem; Meropenem
newer second-gen carbapenem	Biapenem
Biapenems are stable to ______ and resistant to most __________ broad spectrum antibacterial activity (aerobic G- and G+; anaerobes)	DHP-1; Beta-lactamases

Resource summary

	Created by aaudreylynnn over 10 years ago