14036244
| Question | Answer |
| Indications | Type 1 diabetes Type 2 diabetes inadequately controlled with diet, exercise and oral antidiabetic drugs, and where oral antidiabetic drugs cannot be used |
| Actions | Increase or restore ability to metabolise glucose by enhancing cellular glucose uptake inhibit endogenous glucose output and lipolysis. |
| Pharmacokinetics (absorption) | Well absorbed from subcutaneous abdominal injection sites, not as well absorbed in other sites |
| Pharmacokinetics (distribution) | Does not enter breast milk or cross the placenta |
| Metabolism & excretion | Mostly metabolised by the liver, with the remained excreted by the kidneys. Also metabolised at a cellular level. |
| Interactions | Caution should be used when taking other drugs that decrease glucose levels in the blood such as MAOIs, betablockers, salicylates or alcohol. Dose should be adjusted accordingly. |
| Nursing assessment requirements | BGL level pre and post Baseline vital signs to assist with detecting hypo/hyperglycaemia Monitor person's response to administration |
| Education | Diabetes education: signs of hypoglycaemia, diet, exercise. Consider referral to diabetes education. |
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