Created by Yean Ji Jung
over 4 years ago
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Question | Answer |
Selective estrogen reuptake modulators (SERM) | Raloxifene (Evista) |
Mechanism of Action | Produces estrogen like effects on bone. Reduces reabsorption of bone |
Side Effects | Stroke Pulmonary embolism DVT, VTE |
Nursing Actions | Monitor bone density Take vit d and calcium and exercise Teratogenic |
Bisphosphonates | Alendronate (Fosamax) |
Mechanism of Action | Stops osteoclast activity decreasing bone reabsorption |
Side Effects | GI disturbances Vision changes Photosensitivity |
Nursing Actions | Give 30 mins before other meds or food Sit/stand after med admin for 30 mins Take with full glass of water |
Hormone | Calcitonin (Miacalcin, Calcimar) |
Mechanism of Action | Inhibits osteoclast activity and increases calcium excretion. Decreases serum calcium levels. |
Side effects | hypocalcemia epistaxis polyuria rhinitis allergic rxn to fish |
Nursing action | Ask allergies to fish! Educate on diet high in calcium and vit d Check for hypocalcemia |
Calcium replacements | Calcium carbonate (Tums) |
Mechanism of Action | Non dietary access to calcium. Increase calcium levels |
Side effects | hypercalcemia kidney stones |
Nursing Actions | Monitor Ca levels give 1 hr before or 2 hrs after other meds give 1 hr after meals |
Disease Modifying Anti-Rheumatic Drugs (DMARD) nonbiological | Methotrexate (Rheumatrex) |
Mechanism of Action | Decreases body's immune system |
Side effects | low WBC, RBC hair loss photosensitivity immunosuppression |
Nursing actions | Teratogenic avoid sunlight NO LIVE VACCINES hydrate pt |
DMARD biological | Hydroxychloroquine (Plaquenil) |
Tumor Necrosis Factor Alpha (TNF) | Encourages inflammation |
Mechanism of action of DMARD biological | Blocks TNF reducing inflammation |
Side effects | immunosuppression |
Nursing Action | Monitor and trend lab values monitor vitals |
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