Knowledge Acquisition & Use for CDS

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Board Exam ClinicalDecisionSupport (CDS) Flashcards on Knowledge Acquisition & Use for CDS, created by Michael Riben on 08/10/2013.
Michael Riben
Flashcards by Michael Riben, updated more than 1 year ago
Michael Riben
Created by Michael Riben about 11 years ago
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Question Answer
how is knowledge acquired? narrow down from a broad subject to a specific topic with extraction of data
What are the 4 approaches to knowledge representation? Clinical algorithms, bayesian statistitcs, production rules, and scoring/heuristics
What are benefits of clinical algorithms? Knowledge is explicit, knowledge is easy to encode, uses a flow chart with information nodes and decision nodes
What are limitations of Clinical Algorithms No accounting for prior results, no ability to pursue new etiologies, treatments, etc, and new knowledge is difficult to generate
What are Bayesian statistics? based on bayes theorem, which calculates the probability based on prior probability and new informaiton
Give an example of Bayes Theorem CDS Leeds Abdominal Pain System in 1970's, performed better than physicians
What are limitations of Bayesian Statistics? findings are not conditionally independent, diseases may not be mutually exclusive, and multiple findings result in high computational complexity
What are production rules? Knowledge encoded in If-Then rules to arrive at a diagnosis
What are the two types of Production rules systems Forward Chaining and Backward chaining.
What is a backward chaining system? systems pursues goals and asks questions to reach goal
what is forward chaining system? similar to clinical algorithm with a computer following a prescribed path to reach an answer
what was the first rule based expert system in medicine? Mycin
What was Mycin used for? suggests treatments for infectious diseases in meningitis and bacteremia using a backward chaining approach by asking questions relentless to reach a diagnosis
What were the limitations of Rule Based Systems? depth first searching could lead to focus in wrong area, large and difficult to maintain rule knowledge base, slow and time consuming to use the system
What is a scoring/heuristic knowlege representation? knowledge is represented as "profiles" of findings that occur with measures of importance and frequency for each finding, most scalable
give 3 examples of heuristic knowlege representation expert systems? Iliad, Dxplain, and QMR
what is the import of finding in QMR? how important a measure of a finding is to explain
What is the Evoking Strength in QMR? The likelihood of a disease given a finding = scored 0-non-specific to 5-pathognomonic
What is the Frequency score in QMR? the likelihood of a finding given a disease 0-occurs rarely to 5(occurs in all cases)
What were the limitations of QMR? Long learning curve, time consuming data entry, diagnosis is not a major issue for clinicians, incomplete knowledge bases,
What realization occurred in CDS in early 90's? diagnostic process is too complex for computers, greek oracle model was inappropriate model for medical usefulness
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