Cellular Biology

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Chapter 13
Kelsey Hopland
Flashcards by Kelsey Hopland, updated more than 1 year ago
Kelsey Hopland
Created by Kelsey Hopland over 9 years ago
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Cell Theory 1. all living things are composed of cells 2. the cell is the basic functional unit of life 3. the chemical reactions of life take place inside the cell 4. cells arise only from pre-existing cells 5. cells carry genetic information in the form of DNA, which is passed from parent cell to daughter cell
biological kingdoms 1. Bacteria 2. Archaea 3. Protista 4. Fungi 5. Plantae 6. Animalia
organelles nucleus, ribosomes, endoplasmic reticulum, Golgi apparatus, vesicles, vacuoles, lysosomes, mitochondria, chloroplasts, centrioles
cell membrane encloses the cell and exhibits selective permeability consists of phospholipid bilayer permeable to small and non-polar hydrophobic molecules
nucleus controls the activities of the cell, including division contains DNA complexed with histones to form chromosomes
nucleolus dense structure in the nucleus where ribosomal RNA (rRNA) synthesis occurs
ribosome sites of protein production synthesized by the nucleolus found in cytoplasm and lining the outer membrane of the endoplasmic reticulum
endoplasmic reticulum network of membrane-enclosed spaced involved in transport of materials throughout the cell two types: rough, smooth
rough endoplasmic reticulum contains ribosomes and plays an important role in the production of proteins
smooth endoplasmic reticulum does not contain ribosomes, involved with metabolism and production of lipids
Golgi apparatus modifies and repackages vesicles (and their contents) received from the smooth ER via glycosylation distributes repacked vesicles to the cell surface via exocytosis
mitochondria composed of inner/outer phospholipid bilayer sites of aerobic respiration, hence major energy supplier of the cell produces ATP
cytoplasm center for major portion of metabolic activity contains organelles, cytosol promotes cyclosis
cytosol cellular fluid contained within cell membrane
cyclosis streaming movement within cell, occurs in cytoplasm
vacuole/vesicle membrane-bound sacs involved in the transport and storage of materials that are ingested, secreted, processed, or digested by the cell vacuoles are larger, more commonly found in plants
centrioles non-bound organelle involved in spindle organization during cell division lie in region called the centrosome not found in plant cells
lysosomes membrane-bound vesicles that contain hydrolytic enzymes involved in intracellular digestion
autolysis a process by which a cell "commits suicide" by rupturing the membrane of the lysosome to prompt the release of hydrolytic enzymes
cytoskeleton a mechanism for support, maintenance of cellular morphology, and motility composed of microtubules, microfilaments, and intermediate filaments
microtubules hollow rods of polymerized tubulin that radiate throughout the cell and provide support provide framework for organelle movement examples: centrioles, cilia, flagella
microfilaments comprised of actin, solid rods which are important in cell movement and support move materials across the plasma membrane example: muscle contraction
simple diffusion net movement of dissolved particles down a concentration gradient passive process which requires no energy
osmosis diffusion of water from region of lower solute concentration to a region of higher solute concentration
hypertonic a condition in which the cytoplasm of a cell has a lower solute concentration than the extracellular medium
plasmolysis shriveling of the cell due to external passive diffusion of water in hypertonic conditions
hypotonic a condition in which the extracellular medium is less concentrated than the cytoplasm of the cell
lysis swelling and bursting of a cell due to internal passive diffusion in hypotonic conditions
isotonic a condition in which the extracellular environment has the same solute concentration as the cell cytoplasm
facilitated diffusion net movement of dissolved particles down their concentration gradient through channels or carrier proteins energy independent passive transport
active transport net movement of dissolved particles against their concentration gradient with the help of transport proteins requires energy
energy-independent carriers carrier molecule which facilitates the movement of compounds along a concentration gradient
symporters carrier molecules which move two or more ions/molecules in the same direction across the membrane
antiporters exchange one or more ions/molecules for another ion/molecule across the membrane
pumps energy-dependent carriers (e.g. sodium-potassium pump)
endocytosis process in which the cell membrane invaginates, forming a vesicle that contains extracellular medium forms: pinocytosis, phagocytosis
pinocytosis ingestion of fluids or small particles
phagocytosis engulfing of large particles
exocytosis process by which an internal vesicle fuses with the cell membrane and releases a large volume of contents to the outside (e.g. neurotransmitters)
Brownian movement a mechanism of intracellular movement in which kinetic energy spreads small suspended particles throughout the cytoplasm
cyclosis also known as streaming; a mechanism of intracellular movement in which the circular motion of cytoplasm around the cell transports molecules
intracellular movement of the endoplasmic reticulum a mechanism of intracellular movement in which the ER forms a network of channels throughout the cytoplasm, providing direct continuous passageway from the plasma membrane to the nuclear membrane
methods of extracellular circulation 1. diffusion 2. circulatory system
cell division process by which a cell doubles its organelles and cytoplasm, replicates DNA, and then divides in two
unicellular division purpose is reproduction
multicellular division method of growth, development, and replacement
cell cycle entire series of events leading to cellular replication involves mitosis, meiosis
interphase period of growth and chromosome replication stages: G1, S, G2
A. centromere B. chromatids C. sister chromatids *each colored unit is referred to as a chromosome
G1 initiation of interphase in which active growth of the cell and synthesis of proteins occurs
S interphase period of DNA synthesis
G2 period of preparation for division in which growth and synthesis of proteins occurs
M last phase of the cellular cycle in which mitosis or meiosis occurs
mitosis the division and distribution of the cell's DNA to its two daughter cells such that each cell receives a complete copy of the original gamete occurs in somatic cells
karyokinesis nuclear division
cytokinesis cellular division which occurs at the conclusion of telophase, involving the formation of a cleavage furrow and the slow pinching of the equator which results in separation
metaphase formation of the metaphase plate via the alignment of the chromosomes to the equator of the cell by spindle attachment to the kinetochore
kinetochore protein location on the centromere
anaphase separation of the sister chromatids due to splitting of centromere additionally, pulling of material toward opposing poles by shortening of spindle fibers which are composed of microtubules
telophase phase in which the spindle apparatus dissolves and a new nuclear membrane forms around the duplicated and separated chromosomes
meiosis process by which sex cells are produced via the fusion of two separate gametes produces haploid cells
first meiotic division produces two intermediate daughter cells with N chromosomes and sister chromatids
prophase 1 condensation of chromatin, formation of spindle apparatus, dissolution of nuclear membrane synapsis occurs and a tetrad is formed
synapsis process by which homologous chromosomes come together and intertwine
tetrad state in which each synaptic pair of homologous chromosomes contains four chromatids
crossing over corresponding breakage of chromatids of homologous chromosomes resulting in exchange of equivalent pieces of DNA occurs at chiasmata
metaphase 1 stage in which tetrads align at the equatorial plane and each pair attaches to a separate spindle fiber at the kinetochore
anaphase 1 stage in which disjunction occurs, involving the separation of homologous pairs being pulled to opposite poles of the cell results in creation of unique daughter cells
nondisjunction occurs during meiosis anaphase 1 when cells do not separate appropriately, forming daughter cells with the incorrect number of chromosomes
telophase 1 stage in which the formation of the nuclear membrane occurs note: at this point, the chromosomes still consist of sister chromatids joined at the centromere
second meiotic division similar to mitosis, however not preceded by chromosomal replication chromosomes align at the equator, separate to opposite poles, a new nuclear membrane is formed note: new cels are haploid
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