31018419
Description
Flashcards by Lauren Parker, updated more than 1 year ago
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Created by Lauren Parker
over 3 years ago
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| Question | Answer |
| At the lungs what is the ppO2 and why? | ppO2 is high therefore Hb is saturated with O2. |
| Why is a steep drop in % saturation in a slight change of ppO2 an advantage? What would the gradient look like? | Muscles are supplied with oxygen much faster |
| What happens to the affinity of oxygen from hb as blood travels to respiring tissues and why is this important? | affinity of O2 from hb decreases important because O2 has to be taken up by the muscles |
| What is the ppO2 at respiring tissues? What happens to hb? | low ppO2 and hb loses its O2 |
| if hb loses it's O2 is it more or less saturated? | less |
| what do dissociation graphs show? | show % saturation of hb with oxygen against the ppO2 in the tissues |
| what does ppO2 mean? | partial pressure of oxygen = concentration of O2 in tissues |
| when there is an increase in CO2 concentration where does the gradient move to and what do we call this? | gradient shifts right this is called a bohr shift |
| why is a bohr shift an advantage? | when excercising, the hb has a lower affinity for O2 and loses it quicker to the muscles therefore, they can continue to respire aerobically |
| when might a bohr shift occur? | when carbon dioxide levels rise eg in excercise |
| is there more or less O2 in the atmosphere at altitude? | less |
| how might a person's blood differ if they live at high altitudes than if they live at regular altitudes? | at high altitudes a person will have: - an increased erythrocyte count - an increased haemoglobin count - their hb has a higher affinity for O2 |
| why might a person who lives at high altitude's hb have a higher affinity for O2? | To make up for the lack of O2 in the air |
| How might a peruvian's dissociation curve differ to a european's? | a peruvian has a steeper curve (on the left) with saturated Hb at a lower ppO2 in lungs, and a quicker release to respiring tissues |
| will a foetus have a higher affinity for O2 than their mother? why? will the foetus' gradient be further left or right? | foetal hb must have a higher O2 affinity than mother as the foetus takes O2 from mothers blood the foetus has a very steep curve to the left which means that foetal Hb will give O2 to the growing tissues quickly |
| what is myoglobin? | a pigment in muscles that acts as a store of O2. |
| does myoglobin have a lower affinity for O2 than hb? Why/ why not? | myoglobin has a higher affinity for O2 than hb so that it can take O2 from Hb but will quickly release O2 when muscles need it (very steep curve) |
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