Created by gina_evans0312
about 11 years ago
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Question | Answer |
Genotype | Genetic Makeup- of an individual, group or species |
Phenotype | Viewable Organism Traits |
Allele | One of a series of possible alternative forms of a given gene |
Gene | Hereditary unit that occupies a specific locus in the organism's genome |
Amorph Mutation | Genetic Null- Complete loss of all gene function |
Hypomorph | Reduced gene function |
Hypermorph | Increased gene function |
Antimorph | A mutant that inhibits wild type function |
Neomorph | New gene function |
Dominance- Referring to Allelic interaction | Effects genotype, not inheritence |
Phenotypic Investigation | Used to determine dominance and recessiveness in genotypes |
Recessive Alleles | Only effect phenotype when present in homozygous form |
Yeast- Diploid or Haploid? | Exists in both forms- if starved of nitrogen, they form haploid spores |
Yeast as a Model Organism | Dominant/Recessive traits obvious when spores breed together |
Mutagenesis | An event capable of causing mutation- done in labs using chemicals/UV |
Allelic Mutations | Where induced mutations all occur to the same allele |
Non-Allelic Mutations | Mutations occurring to different alleles that effect the same pathway |
Dominant Negative Mutation | A mutation that adversely effects the activity of the wild type allele (if present) |
TRF2 | A protein that binds to telomeric DNA using it's Myb domain |
Mutant TRF2 | Example of a dominant negative mutation- mutant TRF2 lacking a Myb domain strips the w.t of its Myb domain |
Myb | Part of TRF2 required to bind to the telomere |
Epistasis | Where the presence of one GENE masks the expression of another |
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