Created by prettypriyaz
almost 11 years ago
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Question | Answer |
Genetic Control of cell division | 1. Cell division is controlled by genes. Most cells divide to ensure cells are replaced. |
In normal cells, two types of genes control cell division. | 1. Proto-oncogenes stimulate cell division 2. Tumour suppressor gene slow cell division |
Role of Proto-oncogenes-01 | In a normal cell, growth factors attach to a receptor protein on the cell surface membrane and, via relay proteins in the cytoplasm. |
Examples of growth factors | 1. Proteins 2. Hormones |
Role of proto-oncogenes -02 | Gene mutation can cause proto-oncogene to mutate into oncogenes. 1. Receptor protein on the cell-surface membrane can be permanently activated, so the cell division is activated even in the absence of growth factors. 2. The oncogene may code for a growth factor, that is then produced in excessive amounts, and stimulate excessive cell division. |
Role of tumour suppressor genes | 1. In normals cells, this gene maintain normal rates of division and prevent the formation of tumours. 2. If a tumour suppressor gene is mutated it is inactivated so it stops inhibiting cell division, which therefore increases. |
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