Created by Ahmed Radwan9332
over 8 years ago
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Question | Answer |
Penicillin (G, VK, benzathine) work on which organisms. | viridans group strept. + Streptococcus pyrogens + oral anaerobes + syphilis + Leptospira. |
Ampicillin & amoxicillin work on which organisms | Same as penicillins + Lyme disease, HELPS (H. influenza , E. coli, Listeria, Proteus, Salmonella) |
Penicillins are best initial therapy in? | - Otitis media - Dental infections. - Endocarditis prophylaxis. - Lyme limited to rash, joint, or 7th cranial nerve. - UTI in pregnants. - Listeria monocytogenes. - Enterococcal infections. |
Penicillinase - resistant penicillins (oxacillin, cloxacillin, dicloxacillin, nafcillin) used to treat ? | - Skin infections (Cellulitis, impetigo, erysipelas) - Endocarditis. - Meningitis. - Bacteremia from staph. - Osteomyelitis and septic arthritis only when proven sensitive. |
When is Methicillin the right answer? | Never |
(Pipracillin, ticarcillin, azolocillin, mezlocillin) are best initial therapy for? | - Cholecystitis. - Ascending cholangitis. - Pyelonephritis. - Bacteremia. - Hospital acquired and ventilator associated pneumonia. - Neutropenia and fever. |
What is the only cephalosporin that will cover MRSA? | Ceftaroline |
All cephalosporins in all classes cover? | - Group A, B, C strept. - Viridans strept. - E. coli. - Klebsiella. - Proteus mirabilis. |
First Gen cephalosporin examples? | Cefazolin, cefadroxyl, cepharadrine, cephalexin. |
First gen cephalosporin used to treat ? | - Staph. - Strept. ( except enterococcus) - E. coli. - osteomyelitis. - septic arthritis. - cellulitis. |
Only cephalosporin that cover anaerobes are? | Cefotetan + cefoxitin ( both are 2nd gen) |
2nd gen cephalosporin examples. | Cefotetan cefoxitin cefuroxime. laracarbef cefaclor cefprozil |
Best initial therapy for Pelvic inflammatory disease? | cefotetan or cefoxitin combined with doxycyclin. |
Dangerous side effect of cefotetan and cefoxitin. | - increase risk of bleeding. - disfulfiram like reaction with alcohol. |
3rd gen cephalosporin examples. | ceftriaxone, cefotaxime, ceftazidime. |
Ceftriaxone used to treat. | - 1st line for pneumococcus ( even when partially insensistive) - Meningitis. - community acquired pneumonia( in combination with macrolides) - Gonorrhea. - Lyme involving heart or brain. |
why avoid ceftriaxone in neonates? | because of impaired biliary metabolism. ( used cefotaxime) |
Cefepime used for? | - neutropenia + fever. - Ventilator associated pneumonia. |
What is used with neutropenic fever? | - Pipracillin with tazobactam. - Carbapenems. Cefepime. |
Examples of carbapenems. | Imipenem. Meropenem. Doripenem. Entrapenem ( different in NOT covering Pseudomonas) |
What is Aztreonam? | Only drug in the monobactams and used to treat Pseudomonas. |
Best therapy for community acquired pneumonia? | Fluroquinolones |
The only Quinolone used for diverticulitis and GI infection as single agent is? | Moxifloxacin. ( Does not need metronidazol) |
Side effects of Quinolones | - Bone growth abnormality in children and pregnant. - Tendonitis and achillis tendon rupture. |
Uses of Fluoroquinolones? | - Gram - ve bacilli including pseudomonas. - Cipro for cystitis and pyelonephritis. - Community aquired pneumonia. |
Uses of Aminoglycosides. (Gentamicin, Tobramycin, Amikacin) | - Gram -ve bacilli (bowl, urine, bactremia) - Synegestic with betalactam AB for enterococci and staph. |
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