General Infection Types (Pneumonia & Legionella)

Question	Answer
Upper RT Infection- Locations	Nasal cavity, pharynx & tonsils
Upper RT Infection- Agent	Viruses- so no antibiotics
Lower RT Infection- Location	Bronchi and lungs
Lower RT Infection- Agents	Tend to be bacterial
Pneumonia- Characteristics	Alveoli become fluid filled
Pneumonia- Acquisition	Different settings- Community & Nosocomial (Hospital Acquired) caused by 2 different bugs
Atypical Pneumonia- Difficulty	Symptoms aren't typical so hard to diagnose
Atypical Pneumonia- Agents	Vary greatly, so antibiotics vary greatly
Legionella pneumophillia- Gram Staining	Gram -ve rod
Legionella pneumophillia- Mortality	Higher mortality than other strains
Legionella pneumophillia- Vaccine	Related to its ability to divide in macrophages
Legionella pneumophillia- Macrophage Invasion	After phagocytosis, it compartmentalises arund mitochondria and ER vesibles (Forming an LCV)
Legionella pneumophillia- Immune Avoidance	Can avoid the innate immunity, but is detected by the t-lyphocytes of the adaptive

Resource summary

	Created by gina_evans0312 over 10 years ago